Systemic lupus erythematosus: Diagnosis and clinical management
Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement a...
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| Published in | Journal of autoimmunity Vol. 96; pp. 1 - 13 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.01.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted molecular pathways converging into the SLE clinical phenotype. The SLE complex pathogenesis involves multiple cellular components of the innate and immune systems, presence of autoantibodies and immunocomplexes, engagement of the complement system, dysregulation of several cytokines including type I interferons, and disruption of the clearance of nucleic acids after cell death. Use of immunomodulators and immunosuppression has altered the natural course of SLE. In addition, morbidity and mortality in SLE not only derive from direct immune mediated tissue damage but also from SLE and treatment associated complications such as accelerated coronary artery disease and increased infection risk.
Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. This includes 1) lifestyle changes such as avoidance of ultraviolet light; 2) prevention of comorbidities including coronary artery disease, osteoporosis, infections, and drug toxicities; 3) use of immunomodulators (i.e. hydroxychloroquine and vitamin D); and 4) immunosuppressants and targeted therapy. We also review new upcoming agents and regimens currently under study.
•Classification criteria are a helpful diagnostic framework to confirm clinical judgement.•Hydroxychloroquine is the cornerstone of medical therapy in lupus.•Immunosuppression and targeted therapies are paramount for renal and severe extra-renal lupus manifestations.•New therapies targeting the Th17, BAFF, JAK/STAT, and calcineurin pathways showed positive phase 2b trial results. |
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| AbstractList | Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted molecular pathways converging into the SLE clinical phenotype. The SLE complex pathogenesis involves multiple cellular components of the innate and immune systems, presence of autoantibodies and immunocomplexes, engagement of the complement system, dysregulation of several cytokines including type I interferons, and disruption of the clearance of nucleic acids after cell death. Use of immunomodulators and immunosuppression has altered the natural course of SLE. In addition, morbidity and mortality in SLE not only derive from direct immune mediated tissue damage but also from SLE and treatment associated complications such as accelerated coronary artery disease and increased infection risk.
Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. This includes 1) lifestyle changes such as avoidance of ultraviolet light; 2) prevention of comorbidities including coronary artery disease, osteoporosis, infections, and drug toxicities; 3) use of immunomodulators (i.e. hydroxychloroquine and vitamin D); and 4) immunosuppressants and targeted therapy. We also review new upcoming agents and regimens currently under study. Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted molecular pathways converging into the SLE clinical phenotype. The SLE complex pathogenesis involves multiple cellular components of the innate and immune systems, presence of autoantibodies and immunocomplexes, engagement of the complement system, dysregulation of several cytokines including type I interferons, and disruption of the clearance of nucleic acids after cell death. Use of immunomodulators and immunosuppression has altered the natural course of SLE. In addition, morbidity and mortality in SLE not only derive from direct immune mediated tissue damage but also from SLE and treatment associated complications such as accelerated coronary artery disease and increased infection risk. Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. This includes 1) lifestyle changes such as avoidance of ultraviolet light; 2) prevention of comorbidities including coronary artery disease, osteoporosis, infections, and drug toxicities; 3) use of immunomodulators (i.e. hydroxychloroquine and vitamin D); and 4) immunosuppressants and targeted therapy. We also review new upcoming agents and regimens currently under study.Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted molecular pathways converging into the SLE clinical phenotype. The SLE complex pathogenesis involves multiple cellular components of the innate and immune systems, presence of autoantibodies and immunocomplexes, engagement of the complement system, dysregulation of several cytokines including type I interferons, and disruption of the clearance of nucleic acids after cell death. Use of immunomodulators and immunosuppression has altered the natural course of SLE. In addition, morbidity and mortality in SLE not only derive from direct immune mediated tissue damage but also from SLE and treatment associated complications such as accelerated coronary artery disease and increased infection risk. Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. This includes 1) lifestyle changes such as avoidance of ultraviolet light; 2) prevention of comorbidities including coronary artery disease, osteoporosis, infections, and drug toxicities; 3) use of immunomodulators (i.e. hydroxychloroquine and vitamin D); and 4) immunosuppressants and targeted therapy. We also review new upcoming agents and regimens currently under study. Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted molecular pathways converging into the SLE clinical phenotype. The SLE complex pathogenesis involves multiple cellular components of the innate and immune systems, presence of autoantibodies and immunocomplexes, engagement of the complement system, dysregulation of several cytokines including type I interferons, and disruption of the clearance of nucleic acids after cell death. Use of immunomodulators and immunosuppression has altered the natural course of SLE. In addition, morbidity and mortality in SLE not only derive from direct immune mediated tissue damage but also from SLE and treatment associated complications such as accelerated coronary artery disease and increased infection risk. Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. This includes 1) lifestyle changes such as avoidance of ultraviolet light; 2) prevention of comorbidities including coronary artery disease, osteoporosis, infections, and drug toxicities; 3) use of immunomodulators (i.e. hydroxychloroquine and vitamin D); and 4) immunosuppressants and targeted therapy. We also review new upcoming agents and regimens currently under study. •Classification criteria are a helpful diagnostic framework to confirm clinical judgement.•Hydroxychloroquine is the cornerstone of medical therapy in lupus.•Immunosuppression and targeted therapies are paramount for renal and severe extra-renal lupus manifestations.•New therapies targeting the Th17, BAFF, JAK/STAT, and calcineurin pathways showed positive phase 2b trial results. Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental triggers, and the hormonal milieu, interplay in disease development and activity. Clinical manifestations and the pattern of organ involvement are widely heterogenous, reflecting the complex mosaic of disrupted molecular pathways converging into the SLE clinical phenotype. The SLE complex pathogenesis involves multiple cellular components of the innate and immune systems, presence of autoantibodies and immunocomplexes, engagement of the complement system, dysregulation of several cytokines including type I interferons, and disruption of the clearance of nucleic acids after cell death. Use of immunomodulators and immunosuppression has altered the natural course of SLE. In addition, morbidity and mortality in SLE not only derive from direct immune mediated tissue damage but also from SLE and treatment associated complications such as accelerated coronary artery disease and increased infection risk. Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. This includes 1) lifestyle changes such as avoidance of ultraviolet light; 2) prevention of comorbidities including coronary artery disease, osteoporosis, infections, and drug toxicities; 3) use of immunomodulators (i.e. hydroxychloroquine and vitamin D); and 4) immunosuppressants and targeted therapy. We also review new upcoming agents and regimens currently under study. |
| Author | Petri, Michelle Fava, Andrea |
| AuthorAffiliation | 1 Johns Hopkins University School of Medicine 1830 East Monument Street, Suite 7500 Baltimore, MD 21205 |
| AuthorAffiliation_xml | – name: 1 Johns Hopkins University School of Medicine 1830 East Monument Street, Suite 7500 Baltimore, MD 21205 |
| Author_xml | – sequence: 1 givenname: Andrea surname: Fava fullname: Fava, Andrea – sequence: 2 givenname: Michelle orcidid: 0000-0003-1441-5373 surname: Petri fullname: Petri, Michelle email: mpetri@jhmi.edu |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30448290$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.4049/jimmunol.1402793 10.1016/j.jaad.2010.06.018 10.1111/j.1749-6632.1995.tb17369.x 10.1177/0961203313502864 10.1002/art.34473 10.1172/jci.insight.93009 10.1073/pnas.93.4.1624 10.3899/jrheum.150671 10.1002/art.40137 10.1038/nri2849 10.1002/acr.21664 10.1191/0961203302lu158oa 10.1002/art.24937 10.1002/cphy.c110063 10.3899/jrheum.160041 10.2165/11310780-000000000-00000 10.1002/art.22157 10.1136/ard.2006.068676 10.1001/jama.2018.7028 10.1177/0961203314540967 10.1002/art.1780400928 10.1371/journal.pone.0132724 10.1053/j.ajkd.2017.03.008 10.1177/0961203316645205 10.1016/j.abb.2012.04.001 10.1002/art.1790080305 10.1093/rheumatology/ken121 10.1177/0961203317739129 10.1038/sj.ki.5001630 10.1002/art.38720 10.2215/CJN.02271205 10.1002/art.27233 10.1038/nri.2017.1 10.1016/S0140-6736(18)31363-1 10.1182/blood-2011-11-392985 10.1002/art.10364 10.1002/art.38074 10.1073/pnas.0909927107 10.1038/nm.1857 10.1002/1529-0131(200110)45:5<419::AID-ART360>3.0.CO;2-X 10.1111/j.1572-0241.2006.00538.x 10.1002/art.25052 10.4081/reumatismo.2012.307 10.1172/JCI16432 10.1002/art.40360 10.1002/acr.20133 10.1631/jzus.B1200057 10.1111/j.1365-2133.1997.tb03655.x 10.1038/nri2572 10.1111/j.1523-1755.2004.00443.x 10.1177/0961203312442259 10.1002/art.1780380415 10.1046/j.1365-2133.2003.05379.x 10.1124/jpet.107.127209 10.1002/art.38239 10.1002/art.1780251101 10.1002/art.1780300301 10.1002/art.20692 10.1136/ard.2009.120329 10.1186/s13075-015-0726-y 10.1002/art.22449 10.1177/0961203313519159 10.1016/j.jaut.2015.08.004 10.1038/nrrheum.2016.175 10.1191/0961203306lu2305xx 10.1016/j.cell.2016.05.034 10.1073/pnas.0337679100 10.1001/archdermatol.2011.342 10.1191/0961203306lu2299oa 10.1002/art.1780170602 10.3899/jrheum.080828 10.1177/0961203307086267 10.1159/000086440 10.1007/s11926-004-0011-6 10.1002/art.10368 10.1074/jbc.C600321200 10.1016/0002-9343(94)90151-1 10.1056/NEJMoa043731 10.1191/096120300680198935 10.1136/annrheumdis-2011-200937 10.1159/000101471 10.1053/j.ajkd.2010.08.036 10.1136/ard.2005.040907 10.18632/oncotarget.19057 10.1002/art.23177 10.1126/scitranslmed.3001201 10.1055/s-2004-861553 10.3899/jrheum.110532 10.1136/ard.2008.101766 10.1016/j.jaut.2018.03.003 10.1002/art.39962 10.1161/JAHA.116.003815 10.1177/0961203306071872 10.3899/jrheum.080212 10.1093/rheumatology/kep396 10.3109/s10165-009-0213-x 10.1002/art.1780380615 10.1016/S0140-6736(96)03032-2 10.1038/nature09102 10.4065/83.11.1203 10.1016/S0002-9343(99)80135-1 10.1002/art.20798 10.1136/ard.2007.077594 10.1038/nrrheum.2016.186 10.1002/art.1780180106 10.1093/ndt/gfh739 10.1084/jem.20062567 10.1056/NEJMoa0912611 10.3899/jrheum.091366 10.1111/j.1600-6143.2011.03763.x 10.1084/jem.179.4.1317 10.1038/nrrheum.2016.18 10.1001/jama.288.16.2015 10.1586/eci.13.19 10.1056/NEJM200010193431604 10.1016/j.autrev.2015.09.006 10.1007/s40257-016-0173-9 10.1016/S0140-6736(10)61354-2 10.1097/00005792-198409000-00001 10.1136/annrheumdis-2016-210882 10.3899/jrheum.161351 10.1053/berh.2002.0259 10.1681/ASN.2008060665 10.1084/jem.20021553 10.1177/0961203309104392 10.1191/0961203303lu1039oa 10.1177/0961203396005001051 10.1177/0961203396005001031 10.1007/s12013-008-9036-1 10.1172/JCI111929 10.1191/0961203306lu2313oa 10.1177/0961203310365714 10.1136/ard.2007.079418 10.1177/0961203312446386 10.1002/art.30613 10.1016/j.autrev.2018.01.007 10.1002/art.38238 10.1016/j.rdc.2016.12.009 10.1177/0961203310371155 10.1007/BF00856812 10.1016/j.jaut.2016.06.010 10.1038/416603a 10.1002/art.34359 10.1056/NEJM198806023182203 10.1002/art.40222 10.1056/NEJM198007033030107 10.1136/annrheumdis-2014-206456 10.1126/scitranslmed.3001180 10.1136/annrheumdis-2012-201940 10.7326/M14-1030 10.1002/art.24068 10.1002/art.37995 10.1016/j.jaut.2017.04.005 10.1016/j.jaad.2009.12.053 10.1177/0961203314559630 10.1038/ni.3054 10.2215/CJN.11751111 10.3389/fimmu.2018.01088 10.1016/j.berh.2009.04.003 10.1177/0961203311426568 10.1097/00000441-197404000-00005 10.2215/CJN.01910213 10.1046/j.1523-1755.2002.00259.x 10.1073/pnas.0711558105 10.1080/03009740701607042 10.1002/art.20049 10.1056/NEJMoa1014460 10.1177/096120339600500524 10.1097/00005792-199709000-00003 10.1002/acr.23317 10.1002/art.10753 10.1177/0961203313511555 10.1191/0961203305lu2154oa 10.1111/1756-185X.13159 10.1007/s00330-015-3670-y 10.1056/NEJM199101173240303 10.1177/096120339500400303 10.3109/03009749609069986 10.1016/j.jaad.2014.12.025 10.1191/0961203305LU2109OA 10.1016/j.humimm.2016.06.007 10.1016/j.ophtha.2010.11.017 10.1007/s12016-013-8361-3 10.1136/ard.2003.016576 10.1172/JCI23025 10.1016/j.jaut.2017.05.008 10.4049/jimmunol.1700418 10.1002/14651858.CD002922.pub4 10.4049/jimmunol.180.4.2329 10.1097/MED.0000000000000197 10.1191/0961203305lu2039oa 10.1111/j.1440-1797.2012.01574.x 10.1016/j.autrev.2016.09.020 10.1002/art.21039 10.1136/ard.2010.131995 10.1111/j.1365-2133.1992.tb14851.x 10.1093/rheumatology/keg289 10.1177/0961203313493032 10.1067/mjd.2001.114589 10.1097/00005053-198606000-00008 10.1002/1529-0131(200008)43:8<1801::AID-ANR16>3.0.CO;2-O 10.1093/aje/kws130 10.1136/annrheumdis-2012-202844 10.1002/1529-0131(199910)42:10<2026::AID-ANR2>3.0.CO;2-J 10.2174/1568010054022079 10.4049/jimmunol.1201719 10.1093/rheumatology/kep256 10.1136/annrheumdis-2011-201089 10.1016/j.jacc.2011.05.028 10.1002/art.21955 10.1002/art.1780140511 10.1093/ndt/gfr484 10.1002/art.11105 10.1016/S0192-0561(97)00061-1 10.1093/ndt/gfq322 10.4049/jimmunol.1000702 10.1016/j.berh.2017.09.010 10.1681/ASN.2008101028 10.1002/art.37953 10.1002/acr.22621 10.1002/art.23047 10.1002/1529-0131(200105)44:5<1122::AID-ANR193>3.0.CO;2-D 10.1002/art.1780370109 10.1016/j.semarthrit.2014.04.002 10.1016/j.autrev.2008.12.012 10.1007/s40265-015-0534-3 10.1136/ard.2006.057885 10.1007/s11926-016-0621-9 10.1016/j.semarthrit.2008.10.007 10.1177/0961203312450084 10.1056/NEJM198603063141004 10.1136/lupus-2018-000264 10.1093/ndt/gfw068 10.1007/s00125-015-3689-2 10.1136/lupus-2015-000098 10.1177/0961203311411597 |
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| References | Condon, Ashby, Pepper, Cook, Levy, Griffith, Cairns, Lightstone (bib158) 2013; 72 Chasset, Francès, Barete, Amoura, Arnaud (bib64) 2015; 72 Závada, Pešičková, Ryšavá, Horák, Hrnčíř, Lukáč, Rovenský, Vítová, Havrda, Rychlík, Böhmova, Vlasáková, Slatinská, Zadražil, Olejárová, Tegzova, Tesar (bib203) 2014; 23 Magder, Petri (bib162) 2012; 176 Kuhn, Gensch, Haust, Meuth, Boyer, Dupuy, Lehmann, Metze, Ruzicka (bib248) 2011; 64 Garcia-Romo, Caielli, Vega, Connolly, Allantaz, Xu, Punaro, Baisch, Guiducci, Coffman, Barrat, Banchereau, Pascual (bib33) 2011; 3 Chiou, Lan, Lin, Chen, Tsai, Kuan, Lin, Lin, Lee, Chang (bib24) 2004; 13 Wang, Zhu, DeLuca (bib131) 2012; 523 Wakasugi, Gono, Kawaguchi, Hara, Koseki, Katsumata, Hanaoka, Yamanaka (bib76) 2012; 39 Paidassi, Tacnet-Delorme, Garlatti, Darnault, Ghebrehiwet, Gaboriaud, Arlaud, Frachet (bib41) 2008; 180 Hasan, Nyberg, Stephansson, Puska, Hakkinen, Sarna, Ros, Ranki (bib56) 1997; 136 Guiducci, Gong, Xu, Gill, Chaussabel, Meeker, Chan, Wright, Punaro, Bolland, Soumelis, Banchereau, Coffman, Pascual, Barrat (bib40) 2010; 465 Miot, Miot, Haddad (bib61) 2005; 211 Buckley, Guyatt, Fink, Cannon, Grossman, Hansen, Humphrey, Lane, Magrey, Miller, Morrison, Rao, Robinson, Saha, Wolver, Bannuru, Vaysbrot, Osani, Turgunbaev, Miller, McAlindon (bib267) 2017; 69 a Casciola-Rosen, Anhalt, Rosen (bib37) 1994; 179 Magro-Checa, Zirkzee, Huizinga, Steup-Beekman (bib171) 2016; 76 Ginzler, Wofsy, Isenberg, Gordon, Lisk, Dooley (bib194) 2010; 62 Cobo-Ibáñez, Loza-Santamaría, Pego-Reigosa, Marqués, Rúa-Figueroa, Fernández-Nebro, Cáliz, López Longo, Muñoz-Fernández (bib218) 2015; 44 Anderson, Kruszka, Delaney, He, Burke, Alonso, Bild, Budoff, Michos (bib268) 2016; 5 Parikh, Pendergraft, Tumlin, Saxena, Solomons, Huizinga (bib217) 2017; 69 Walling, Sontheimer (bib55) 2009; 10 Gadina, Johnson, Schwartz, Bonelli, Hasni, Kanno, Changelian, Laurence, O'Shea (bib243) 2018 Wallace, Furie, Tanaka, Kalunian, Mosca, Petri, Dörner, Cardiel, Bruce, Gomez, Carmack, DeLozier, Janes, Linnik, de Bono, Silk, Hoffman (bib244) 2018; 392 Fortin, Abrahamowicz, Ferland, Lacaille, Smith, Zummer (bib187) 2008; 59 Lahita, Bradlow, Ginzler, Pang, New (bib148) 1987; 30 Sibbitt, Brooks, Haseler, Griffey, Frank, Hart, Sibbitt (bib92) 1995; 38 Lande, Ganguly, Facchinetti, Frasca, Conrad, Gregorio, Meller, Chamilos, Sebasigari, Riccieri, Bassett, Amuro, Fukuhara, Ito, Liu, Gilliet (bib34) 2011; 3 Fasano, Pierro, Pantano, Iudici, Valentini (bib112) 2017; 44 Wang, Schmid, Rones, Kalish, Yinh, Goldenberg, Lee, McAlindon (bib251) 2010; 363 . Krämer, Montagnino, del Castillo, Margreiter, Sperschneider, Olbricht, Krüger, Ortuño, Köhler, Kunzendorf, Stummvoll, Tabernero, Mühlbacher, Rivero, Arias, Dietl, del Castillo, Pascual, Olbrícht, Kammerl, Krüger, Köhler, Sester, Mühlbacher, Kunzendorf, Hauser, Ponticelli, Bonomini, Tabernero, Rivero, Ancona, Calconi, Cambi, la Greca, Mosca, Selvaggi, Meurisse, Detry, González Molina, Piccoli, Salvadori, Schilling, Raedelli, Arns, Suarez, Rodríguez Algarra, Asensio, Maiorca, Ancona, Sparacino, Morales, Gutierrez, Lauzurica, Verpooten, Sennesael, Heidecke, García, Capdevila, Abendroth, Biesenbach, Altieri, Sorba, Valente, Castagneto, Purroy, Duhoux, Kremar, Stiegler, Schleibner (bib199) 2005; 20 Petri, Roubenoff, Dallal, Nadeau, Selhub, Rosenberg (bib255) 1996; 348 Wolfe, Petri, Alarcón, Goldman, Chakravarty, Katz, Karlson (bib71) 2008; 36 Cooper, Parks (bib19) 2004; 6 Lim, Bayakly, Helmick, Gordon, Easley, Drenkard (bib8) 2014; 66 Petri (bib1) 2002; 16 Wolfe, Petri, Alarcón, Goldman, Chakravarty, Katz, Karlson (bib249) 2009; 36 Mok (bib193) 2007; 36 Borba, Matos, Da Silva Viana, Fernandas, Sato, Lazaretti-Castro (bib266) 2005; 14 Stojan, Petri (bib82) 2016; 25 Babary, Liu, Ayatollahi, Chen, Doo, Uppaluru, Kwak, Kulaga, Modjinou, Olech, Yoo (bib120) 2018; 21 Faul, Donnelly, Merscher-Gomez, Chang, Franz, Delfgaauw, Chang, Choi, Campbell, Kim, Reiser, Mundel (bib198) 2008; 14 Salvatore, Barisoni, Herzenberg, Chander, Nickeleit, Seshan (bib86) 2012; 7 Bernatsky, Boivin, Joseph, Manzi, Ginzler, Gladman, Urowitz, Fortin, Petri, Barr, Gordon, Bae, Isenberg, Zoma, Aranow, Dooley, Nived, Sturfelt, Steinsson, Alarcón, Senécal, Zummer, Hanly, Ensworth, Pope, Edworthy, Rahman, Sibley, El-Gabalawy, McCarthy, Pierre, Clarke, Ramsey-Goldman (bib74) 2006; 54 Helmick, Felson, Lawrence, Gabriel, Hirsch, Kwoh, Liang, Kremers, Mayes, Merkel, Pillemer, Reveille, Stone (bib10) 2008; 58 AstraZeneca, Update on TULIP 1 Phase III Trial for Anifrolumab in Systemic Lupus Erythematosus, (n.d.). Ross, Densen (bib262) 1984; 63 De Boer, Jarbandhan, De Graaf, Mulder, Van Elburg, Van Bodegraven (bib183) 2006; 101 Parks, Cooper, Nylander-French, Sanderson, Dement, Cohen, Dooley, Treadwell, Clair, Gilkeson, Hoppin, Savitz (bib21) 2002; 46 Long, Nie (bib260) 2016; 2 Chen, Liu, Chen, Tang, Fu, Liu, Liao, Yang, Zhang, Chen, Lou, Fu, Kong, Liu, Li, Yu (bib211) 2012; 21 Petri (bib65) 1995; 8 An, Woodward, Sasaki, Minie, Elkon (bib105) 2015; 194 Závada, Pešičkova, Ryšavá, Olejárova, Horák, Hrnčíř, Rychlík, Havrda, Vítová, Lukáč, Rovenský, Tegzova, Böhmova, Zadražil, Hána, Dostál, Tesar (bib202) 2010; 19 Akhter, Burlingame, Seaman, Magder, Petri (bib81) 2011; 20 Petri, van Vollenhoven, Buyon, Levy, Navarra, Cervera, Zhong, Freimuth (bib230) 2013; 65 Pons-Estel, Alarcón, Scofield, Reinlib, Cooper (bib5) 2010; 39 Dai, He, Tsokos, Kyttaris (bib241) 2017; 199 Kuznik, Bencina, Svajger, Jeras, Rozman, Jerala (bib100) 2011; 186 Groom, Fletcher, Walters, Grey, Watt, Sweet, Smyth, Mackay, Mackay (bib231) 2007; 204 Tench, McCarthy, McCurdie, White, D'Cruz (bib253) 2003; 42 Petri, Bello, Fang, Magder (bib143) 2013; 65 Carbotte, Denburg, Denburg (bib94) 1986; 174 Petri (bib102) 1996; 5 Ikezumi, Kanno, Koike, Tomita, Uchiyama, Shimizu, Kawachi (bib196) 2002; 61 Lins, Santiago (bib68) 2015; 25 Mok, To, Yu, Ho (bib208) 2013; 22 Appel, Contreras, Dooley, Ginzler, Isenberg, Jayne, Li, Mysler, Sanchez-Guerrero, Solomons, Wofsy (bib191) 2009; 20 Thompson, Haeney, Reid, Davies, White, Cameron (bib43) 1980; 303 Andreoli, Piantoni, Dall'Ara, Allegri, Meroni, Tincani (bib141) 2012; 21 Lan, Han, Chen (bib219) 2012; 13 Leffler, Ciacma, Gullstrand, Bengtsson, Martin, Blom (bib36) 2015; 17 Crow (bib27) 2017 (bib256) 2002; 288 Burger, Torres, Warren, Caldwell, Hughes (bib14) 1997; 19 Liao, Liu, Zheng, Fan, Peng, Kong, He, Yang, Chen, Tang, Yu (bib197) 2015; 10 Tan, Cohen, Fries, Masi, Mcshane, Rothfield, Schaller, Talal, Winchester (bib46) 1982; 25 Van Vollenhoven, Petri, Cervera, Roth, Ji, Kleoudis, Zhong, Freimuth (bib234) 2012; 71 Giannelou, Mavragani (bib254) 2017; 82 Tiede, Fritz, Strand, Poppe, Dvorsky, Strand, Lehr, Wirtz, Becker, Atreya, Mudter, Hildner, Bartsch, Holtmann, Blumberg, Walczak, Iven, Galle, Ahmadian, Neurath (bib173) 2003; 111 Kirou, Lee, George, Louca, Papagiannis, Peterson, Ly, Woodward, Fry, Lau, Prentice, Wohlgemuth, Crow (bib31) 2004; 50 Yang, Leung, Adamopoulos, Gershwin (bib138) 2013; 45 Lo (bib45) 2016; 18 Ordi-Ros, Sáez-Comet, Pérez-Conesa, Vidal, Mitjavila, Castro Salomó, Cuquet Pedragosa, Ortiz-Santamaria, Mauri Plana, Cortés-Hernández (bib181) 2017; 76 Fang, Chen, Chung, See, Yu, Luo, Kuo, Lai (bib128) 2017; 8 Grootscholten, Ligtenberg, Hagen, Van Den Wall Bake, De Glas-Vos, Bijl, Assmann, Bruijn, Weening, Van Houwelingen, Derksen, Berden (bib176) 2006; 70 Pierangeli, Harris (bib125) 1996; 5 Piantoni, Andreoli, Allegri, Meroni, Tincani (bib142) 2012; 64 Petri, Orbai, Alarcón (bib48) 2012; 64 Kozora, Ellison, West (bib95) 2004; 51 Treml, Hao, Stadanlick, Cancro (bib229) 2009; 53 Blomberg, Nived, Pipkorn, Bengtsson, Erlinge, Sturfelt (bib18) 1994; 37 Furie, Khamashta, Merrill, Werth, Kalunian, Brohawn, Illei, Drappa, Wang, Yoo (bib235) 2017; 69 Dooley, Jayne, Ginzler, Isenberg, Olsen, Wofsy, Eitner, Appel, Contreras, Lisk, Solomons (bib178) 2011; 365 Der, Ranabothu, Suryawanshi, Akat, Clancy, Morozov, Kustagi, Czuppa, Izmirly, Belmont, Wang, Jordan, Bornkamp, Nwaukoni, Martinez, Goilav, Buyon, Tuschl, Putterman (bib269) 2017; 2 Casciola-Rosen, Rosen, Petri, Schlissel (bib38) 1996; 93 Cortés-Hernández, Torres-Salido, Medrano, Tarrés, Ordi-Ros (bib207) 2010; 25 Torrente-Segarra, Salman-Monte, Rúa-Figueroa, Pérez-Vicente, López-Longo, Galindo-Izquierdo, Calvo-Alén, Olivé-Marqués, Ibáñez-Ruán, Horcada, Sánchez-Atrio, Montilla, Rodríguez-Gómez, Díez-álvarez, Martinez-Taboada, Andreu, Fernández-Berrizbeitia, Hernández-Beriain, Gantes, Hernández-Cruz, Pecondón-Español, Marras, Bonilla, Pego-Reigosa, Blanco, Vela-Casasempere, Melero-González, Otón-Sánchez, Tornero-Muriel, Uriarte-Isacelaya, Freire-González, Fito-Manteca, Fernández-Nebro, Narváez, Zea-Mendoza, Rosas-Gómez de Salazar, Ibáñez-Barceló, Pérez-Venegas, de la Torre Ortega, Pérez, Delgado, Rodríguez-Almaraz, Heredia, Soler, Ramírez, Senabre Gallego, Collado, Bernal, Vilamajó, Mas, Murillo, Barranco, Melchor, Fontova, Manrique, Lencastre, Martínez-Losa, Almagro, González-Gay Mantecón, Martíny, del Carmen Bejerano, Blanco, Moreira, Aurrecoechea, Jimeno, Zamorano, Magro, álvarez, Arruabarrena, Mérida, Egües Dubuc, Fanlo, álvarez, Vitovi, Robles, Rodríguez, Oyarzábal, ángeles, López, Romero Barco, López, Pernaute, de Vicuña Pinedo, Expósito, de la Peña, Rubio, González Martín, Gómez, Bohórquez, Hajkhan, Turrión Nieves, Lois Iglesias, Boteanu, Gamir, Alberti, Fernández, Oliva, Stoye, Rodríguez, Rodríguez, de Aspe de la Iglesia, González, Sarabia, Toyos Sáenz de Miera, de la Fuente, Montañés, Sánchez, Pérez, Lozano, úcar Angulo, Lucea, Domínguez, Alegre Sancho, de La Morena Barrio, Valls, Ruiz, Quevedo Vila, Machín, Nóvoa, Fernández (bib250) 2016; 34 Lehmann, Homey (bib39) 2009; 8 Dall'Era, Chakravarty, Wallace, Genovese, Weisman, Kavanaugh, Kalunian, Dhar, Vincent, Pena-Rossi, Wofsy, Alum, Dubois, Kinnman, Picard, Bortolotti, O'Grady, Hill, Nestorov, Salmon (bib245) 2007; 56 Frangou, Bertsias, Boumpas (bib166) 2016 Alarcon Segovia, Cetina (bib60) 1974; 267 Mok, Ying, Yim, Siu, Tong, To, Ng (bib205) 2016; 75 Lateef, Petri (bib182) 2017; 43 V Bonventre (bib134) 2013; 123 Hannah, Casian Andrade (10.1016/j.jaut.2018.11.001_bib115) 2008; 67 Grootscholten (10.1016/j.jaut.2018.11.001_bib177) 2007; 56 Hejazi (10.1016/j.jaut.2018.11.001_bib54) 2016; 17 Ruiz-Irastorza (10.1016/j.jaut.2018.11.001_bib107) 2006; 15 Chen (10.1016/j.jaut.2018.11.001_bib211) 2012; 21 Petri (10.1016/j.jaut.2018.11.001_bib102) 1996; 5 Casciola-Rosen (10.1016/j.jaut.2018.11.001_bib38) 1996; 93 Garcia-Romo (10.1016/j.jaut.2018.11.001_bib33) 2011; 3 Descombes (10.1016/j.jaut.2018.11.001_bib85) 1997; 76 Mok (10.1016/j.jaut.2018.11.001_bib205) 2016; 75 Daniel (10.1016/j.jaut.2018.11.001_bib132) 2008; 324 Alarcon Segovia (10.1016/j.jaut.2018.11.001_bib60) 1974; 267 Navarra (10.1016/j.jaut.2018.11.001_bib233) 2011; 377 Long (10.1016/j.jaut.2018.11.001_bib260) 2016; 2 Carli (10.1016/j.jaut.2018.11.001_bib264) 2016; 3 Tan (10.1016/j.jaut.2018.11.001_bib46) 1982; 25 Johnson (10.1016/j.jaut.2018.11.001_bib2) 1995; 38 Kaplan (10.1016/j.jaut.2018.11.001_bib32) 2012; 189 Leadbetter (10.1016/j.jaut.2018.11.001_bib98) 2002; 416 Hasan (10.1016/j.jaut.2018.11.001_bib56) 1997; 136 Burger (10.1016/j.jaut.2018.11.001_bib14) 1997; 19 Ginzler (10.1016/j.jaut.2018.11.001_bib174) 1975; 18 Treml (10.1016/j.jaut.2018.11.001_bib229) 2009; 53 Petri (10.1016/j.jaut.2018.11.001_bib230) 2013; 65 Liao (10.1016/j.jaut.2018.11.001_bib197) 2015; 10 Veeranna (10.1016/j.jaut.2018.11.001_bib258) 2011; 58 Pons-Estel (10.1016/j.jaut.2018.11.001_bib5) 2010; 39 Petri (10.1016/j.jaut.2018.11.001_bib65) 1995; 8 Borba (10.1016/j.jaut.2018.11.001_bib266) 2005; 14 Miller (10.1016/j.jaut.2018.11.001_bib91) 1992; 239 Condon (10.1016/j.jaut.2018.11.001_bib158) 2013; 72 Thamer (10.1016/j.jaut.2018.11.001_bib163) 2009; 36 Cain (10.1016/j.jaut.2018.11.001_bib155) 2017; 17 Fessler (10.1016/j.jaut.2018.11.001_bib111) 2005; 52 Lanata (10.1016/j.jaut.2018.11.001_bib206) 2010; 19 James (10.1016/j.jaut.2018.11.001_bib20) 2001; 44 Ostendorf (10.1016/j.jaut.2018.11.001_bib69) 2003; 48 Wang (10.1016/j.jaut.2018.11.001_bib251) 2010; 363 a Casciola-Rosen (10.1016/j.jaut.2018.11.001_bib37) 1994; 179 Bernatsky (10.1016/j.jaut.2018.11.001_bib74) 2006; 54 Kuhn (10.1016/j.jaut.2018.11.001_bib248) 2011; 64 Blomberg (10.1016/j.jaut.2018.11.001_bib18) 1994; 37 Birnbaum (10.1016/j.jaut.2018.11.001_bib90) 2009; 60 Parikh (10.1016/j.jaut.2018.11.001_bib217) 2017; 69 Merrill (10.1016/j.jaut.2018.11.001_bib220) 2010; 62 Cortés-Hernández (10.1016/j.jaut.2018.11.001_bib207) 2010; 25 Dooley (10.1016/j.jaut.2018.11.001_bib159) 2016; 68 Aranow (10.1016/j.jaut.2018.11.001_bib227) 2018; 77 Rovin (10.1016/j.jaut.2018.11.001_bib221) 2012; 64 Dillon (10.1016/j.jaut.2018.11.001_bib152) 2005; 4 Tokunaga (10.1016/j.jaut.2018.11.001_bib170) 2007; 66 Petri (10.1016/j.jaut.2018.11.001_bib72) 2010; 37 Katsuyama (10.1016/j.jaut.2018.11.001_bib28) 2018; 9 Ghodke-Puranik (10.1016/j.jaut.2018.11.001_bib13) 2015; 64 Chasset (10.1016/j.jaut.2018.11.001_bib64) 2015; 72 Mok (10.1016/j.jaut.2018.11.001_bib195) 2017; 31 Dai (10.1016/j.jaut.2018.11.001_bib241) 2017; 199 Lo (10.1016/j.jaut.2018.11.001_bib45) 2016; 18 Petri (10.1016/j.jaut.2018.11.001_bib153) 2002; 46 Danowski (10.1016/j.jaut.2018.11.001_bib165) 2006; 33 Lim (10.1016/j.jaut.2018.11.001_bib8) 2014; 66 Závada (10.1016/j.jaut.2018.11.001_bib203) 2014; 23 Leffler (10.1016/j.jaut.2018.11.001_bib36) 2015; 17 Furie (10.1016/j.jaut.2018.11.001_bib235) 2017; 69 Anderson (10.1016/j.jaut.2018.11.001_bib268) 2016; 5 Mok (10.1016/j.jaut.2018.11.001_bib193) 2007; 36 Buckley (10.1016/j.jaut.2018.11.001_bib267) 2017; 69 Costenbader (10.1016/j.jaut.2018.11.001_bib17) 2004; 50 Merrill (10.1016/j.jaut.2018.11.001_bib246) 2018; 70 Petri (10.1016/j.jaut.2018.11.001_bib124) 1996; 25 Zollars (10.1016/j.jaut.2018.11.001_bib70) 2018; 5 Amital (10.1016/j.jaut.2018.11.001_bib140) 2010; 69 Houssiau (10.1016/j.jaut.2018.11.001_bib179) 2010; 69 Williams (10.1016/j.jaut.2018.11.001_bib119) 1994; 21 Yang (10.1016/j.jaut.2018.11.001_bib138) 2013; 45 Singh (10.1016/j.jaut.2018.11.001_bib160) 2016; 43 Wolfe (10.1016/j.jaut.2018.11.001_bib249) 2009; 36 Stojan (10.1016/j.jaut.2018.11.001_bib82) 2016; 25 Ainiala (10.1016/j.jaut.2018.11.001_bib87) 2001; 45 Wozniacka (10.1016/j.jaut.2018.11.001_bib104) 2006; 15 Stojan (10.1016/j.jaut.2018.11.001_bib261) 2017; 76 Edens (10.1016/j.jaut.2018.11.001_bib265) 2015; 22 Sakthiswary R (10.1016/j.jaut.2018.11.001_bib186) 2014; 23 Závada (10.1016/j.jaut.2018.11.001_bib202) 2010; 19 Zarmbinski (10.1016/j.jaut.2018.11.001_bib23) 1992; 19 Krishnan (10.1016/j.jaut.2018.11.001_bib6) 2006; 65 Lahita (10.1016/j.jaut.2018.11.001_bib148) 1987; 30 Wallace (10.1016/j.jaut.2018.11.001_bib52) 2012 Bennett (10.1016/j.jaut.2018.11.001_bib30) 2003; 197 Cairoli (10.1016/j.jaut.2018.11.001_bib122) 2012; 21 Humphrey (10.1016/j.jaut.2018.11.001_bib257) 2016; 83 De Boer (10.1016/j.jaut.2018.11.001_bib183) 2006; 101 Ruiz-Irastorza (10.1016/j.jaut.2018.11.001_bib108) 2010; 69 Der (10.1016/j.jaut.2018.11.001_bib269) 2017; 2 An (10.1016/j.jaut.2018.11.001_bib105) 2015; 194 McMurray (10.1016/j.jaut.2018.11.001_bib147) 2003; 48 Mok (10.1016/j.jaut.2018.11.001_bib109) 2018; 27 Wolfe (10.1016/j.jaut.2018.11.001_bib129) 2010; 62 Dall'Era (10.1016/j.jaut.2018.11.001_bib245) 2007; 56 Firestein (10.1016/j.jaut.2018.11.001_bib53) 2016 Grossman (10.1016/j.jaut.2018.11.001_bib66) 2009; 23 Christopher-Stine (10.1016/j.jaut.2018.11.001_bib77) 2007; 34 Petri (10.1016/j.jaut.2018.11.001_bib97) 2010; 37 Hallegua (10.1016/j.jaut.2018.11.001_bib214) 2000; 9 Generali (10.1016/j.jaut.2018.11.001_bib12) 2017; 83 Yap (10.1016/j.jaut.2018.11.001_bib213) 2012; 17 Lehmann (10.1016/j.jaut.2018.11.001_bib39) 2009; 8 Yi (10.1016/j.jaut.2018.11.001_bib259) 2007; 27 Krämer (10.1016/j.jaut.2018.11.001_bib199) 2005; 20 Labrie (10.1016/j.jaut.2018.11.001_bib146) 1995; 774 Appel (10.1016/j.jaut.2018.11.001_bib191) 2009; 20 Petri (10.1016/j.jaut.2018.11.001_bib88) 2012; 64 Furie (10.1016/j.jaut.2018.11.001_bib232) 2011; 63 Lan (10.1016/j.jaut.2018.11.001_bib219) 2012; 13 Olson (10.1016/j.jaut.2018.11.001_bib79) 2013; 8 Lucas (10.1016/j.jaut.2018.11.001_bib149) 1985; 75 Yang (10.1016/j.jaut.2018.11.001_bib237) 2007; 282 Wakasugi (10.1016/j.jaut.2018.11.001_bib76) 2012; 39 Gladman (10.1016/j.jaut.2018.11.001_bib161) 2003; 30 Brown (10.1016/j.jaut.2018.11.001_bib184) 2016; 12 Sztejnbok (10.1016/j.jaut.2018.11.001_bib175) 1971; 14 Sibbitt (10.1016/j.jaut.2018.11.001_bib92) 1995; 38 Herrinton (10.1016/j.jaut.2018.11.001_bib127) 2016; 43 Carter (10.1016/j.jaut.2018.11.001_bib225) 2013; 65 Tiede (10.1016/j.jaut.2018.11.001_bib173) 2003; 111 Li (10.1016/j.jaut.2018.11.001_bib200) 2012; 27 Wolfe (10.1016/j.jaut.2018.11.001_bib71) 2008; 36 Mok (10.1016/j.jaut.2018.11.001_bib126) 2005; 14 Kuznik (10.1016/j.jaut.2018.11.001_bib100) 2011; 186 Giannelou (10.1016/j.jaut.2018.11.001_bib254) 2017; 82 Crow (10.1016/j.jaut.2018.11.001_bib27) 2017 Zandman-Goddard (10.1016/j.jaut.2018.11.001_bib59) 2012; 21 Petri (10.1016/j.jaut.2018.11.001_bib96) 2008; 35 Means (10.1016/j.jaut.2018.11.001_bib99) 2005; 115 Magro-Checa (10.1016/j.jaut.2018.11.001_bib171) 2016; 76 Der (10.1016/j.jaut.2018.11.001_bib135) 2017; 69 Somers (10.1016/j.jaut.2018.11.001_bib9) 2014; 66 Tsokos (10.1016/j.jaut.2018.11.001_bib11) 2016; 12 John Looney (10.1016/j.jaut.2018.11.001_bib222) 2010; 20 Salvatore (10.1016/j.jaut.2018.11.001_bib86) 2012; 7 West (10.1016/j.jaut.2018.11.001_bib93) 1995; 99 Ehrenstein (10.1016/j.jaut.2018.11.001_bib224) 2016; 12 Wallace (10.1016/j.jaut.2018.11.001_bib247) 2008; 17 Sibbitt (10.1016/j.jaut.2018.11.001_bib89) 1999; 42 Faul (10.1016/j.jaut.2018.11.001_bib198) 2008; 14 Grootscholten (10.1016/j.jaut.2018.11.001_bib176) 2006; 70 Spelman (10.1016/j.jaut.2018.11.001_bib15) 2006; 11 McCune (10.1016/j.jaut.2018.11.001_bib169) 1988; 318 Petri (10.1016/j.jaut.2018.11.001_bib16) 1992; 19 Torrente-Segarra (10.1016/j.jaut.2018.11.001_bib250) 2016; 34 Andreoli (10.1016/j.jaut.2018.11.001_bib141) 2012; 21 Kuhn (10.1016/j.jaut.2018.11.001_bib118) 2011; 65 Orbai (10.1016/j.jaut.2018.11.001_bib80) 2014; 24 Bertsias (10.1016/j.jaut.2018.11.001_bib157) 2012; 71 Petri (10.1016/j.jaut.2018.11.001_bib255) 1996; 348 Hakkim (10.1016/j.jaut.2018.11.001_bib35) 2010; 107 Zonana-Nacach (10.1016/j.jaut.2018.11.001_bib164) 2000; 43 Lafyatis (10.1016/j.jaut.2018.11.001_bib101) 2006; 54 Petri (10.1016/j.jaut.2018.11.001_bib48) 2012; 64 Walling (10.1016/j.jaut.2018.11.001_bib55) 2009; 10 Lateef (10.1016/j.jaut.2018.11.001_bib182) 2017; 43 Thompson (10.1016/j.jaut.2018.11.001_bib43) 1980; 303 Tedeschi (10.1016/j.jaut.2018.11.001_bib49) 2018; 70 Böckle (10.1016/j.jaut.2018.11.001_bib62) 2015; 24 Danchenko (10.1016/j.jaut.2018.11.001_bib3) 2006; 12 Moroni (10.1016/j.jaut.2018.11.001_bib210) 2006; 1 Roberts (10.1016/j.jaut.2018.11.001_bib26) 2017; 69 Shea-Simonds (10.1016/j.jaut.2018.11.001_bib84) 2009; 48 Piantoni (10.1016/j.jaut.2018.11.001_bib142) 2012; 64 Miescher (10.1016/j.jaut.2018.11.001_bib185) 1965; 2 Austin (10.1016/j.jaut.2018.11.001_bib168) 1986; 314 Ruzicka (10.1016/j.jaut.2018.11.001_bib117) 1992; 127 Kuhn (10.1016/j.jaut.2018.11.001_bib58) 2001; 45 Wang (10.1016/j.jaut.2018.11.001_bib131) 2012; 523 Ma (10.1016/j.jaut.2018.11.001_bib238) 2012; 119 Guiducci (10.1016/j.jaut.2018.11.001_bib40) 2010; 465 Bastian (10.1016/j.jaut.2018.11.001_bib73) 2002; 11 Durcan (10.1016/j.jaut.2018.11.001_bib145) 2016; 74 Ferucci (10.1016/j.jaut.2018.11.001_bib7) 2014; 66 MacKay (10.1016/j.jaut.2018.11.001_bib228) 2009; 9 Chen (10.1016/j.jaut.2018.11.001_bib151) 2004; 22 Chiou (10.1016/j.jaut.2018.11.001_bib24) 2004; 13 Chen (10.1016/j.jaut.2018.11.001_bib201) 2011; 57 Piette (10.1016/j.jaut.2018.11.001_bib63) 2012; 148 Ross (10.1016/j.jaut.2018.11.001_bib262) 1984; 63 Paidassi (10.1016/j.jaut.2018.11.001_bib41) 2008; 180 Fortin (10.1016/j.jaut.2018.11.001_bib187) 2008; 59 Ordi-Ros (10.1016/j.jaut.2018.11.001_bib181) 2017; 76 Kozora (10.1016/j.jaut.2018.11.001_bib95) 2004; 51 Kirou (10.1016/j.jaut.2018.11.001_bib31) 2004; 50 Radhakrishnan (10.1016/j.jaut.2018.11.001_bib212) 1994; 42 Dooley (10.1016/j.jaut.2018.11.001_bib178) 2011; 365 Mok (10.1016/j.jaut.2018.11.001_bib208) 2013; 22 Danza (10.1016/j.jaut.2018.11.001_bib263) 2013; 22 Sisirak (10.1016/j.jaut.2018.11.001_ |
| References_xml | – volume: 14 start-page: 639 year: 1971 end-page: 645 ident: bib175 article-title: Azathioprine in the treatment of systemic lupus erythematosus. A controlled study publication-title: Arthritis Rheum. – volume: 57 start-page: 235 year: 2011 end-page: 244 ident: bib201 article-title: Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: a multicenter randomized clinical trial publication-title: Am. J. Kidney Dis. – volume: 194 start-page: 4089 year: 2015 end-page: 4093 ident: bib105 article-title: Cutting edge: antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase–DNA interaction publication-title: J. Immunol. – volume: 58 start-page: 15 year: 2008 end-page: 25 ident: bib10 article-title: Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I publication-title: Arthritis Rheum. – volume: 19 start-page: 265 year: 1992 end-page: 269 ident: bib16 article-title: Antibiotic allergy in systemic lupus erythematosus: a case-control study publication-title: J. Rheumatol. – volume: 9 start-page: 491 year: 2009 end-page: 502 ident: bib228 article-title: Cracking the BAFF code publication-title: Nat. Rev. Immunol. – volume: 9 start-page: 453 year: 2013 end-page: 463 ident: bib139 article-title: Vitamin D and systemic lupus erythematosus: an update publication-title: Expert Rev. Clin. Immunol. – volume: 71 start-page: 1343 year: 2012 end-page: 1349 ident: bib234 article-title: Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response publication-title: Ann. Rheum. Dis. – volume: 15 start-page: 577 year: 2006 end-page: 583 ident: bib107 article-title: Effect of antimalarials on thrombosis and survival in patients with systemic lupus erythematosus publication-title: Lupus – volume: 7 start-page: 1 year: 2017 ident: bib136 article-title: Chronic Vitamin D deficiency induces lung fibrosis through activation of the renin-angiotensin system publication-title: Sci. Rep. – volume: 50 start-page: 3958 year: 2004 end-page: 3967 ident: bib31 article-title: Coordinate overexpression of interferon-?-induced genes in systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 20 start-page: 1 year: 2010 end-page: 10 ident: bib222 article-title: A perspective on B-cell-targeting therapy for SLE publication-title: Mod. Rheumatol. – volume: 10 start-page: 778 year: 2010 end-page: 786 ident: bib42 article-title: The importance of natural IgM: scavenger, protector and regulator publication-title: Nat. Rev. Immunol. – volume: 31 start-page: 1557 year: 2004 end-page: 1559 ident: bib78 article-title: Urine protein-to-creatinine ratio is a reliable measure of proteinuria in lupus nephritis publication-title: J. Rheumatol. – volume: 180 start-page: 2329 year: 2008 end-page: 2338 ident: bib41 article-title: C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition publication-title: J. Immunol. – volume: 14 start-page: 106 year: 2005 end-page: 112 ident: bib126 article-title: Bone mineral density in postmenopausal Chinese patients with systemic lupus erythematosus publication-title: Lupus – volume: 324 start-page: 23 year: 2008 end-page: 33 ident: bib132 article-title: Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile publication-title: J. Pharmacol. Exp. Ther. – volume: 11 start-page: 2675 year: 2011 end-page: 2684 ident: bib216 article-title: The PROMISE study: a phase 2b multicenter study of voclosporin (ISA247) versus tacrolimus in de Novo kidney transplantation publication-title: Am. J. Transplant. – volume: 65 start-page: 1500 year: 2006 end-page: 1505 ident: bib6 article-title: Ethnicity and mortality from systemic lupus erythematosus in the US publication-title: Ann. Rheum. Dis. – volume: 197 start-page: 711 year: 2003 end-page: 723 ident: bib30 article-title: Interferon and granulopoiesis signatures in systemic lupus erythematosus blood publication-title: J. Exp. Med. – volume: 71 start-page: 1771 year: 2012 end-page: 1782 ident: bib157 article-title: Joint european league against rheumatism and european renal association-european dialysis and transplant association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis publication-title: Ann. Rheum. Dis. – volume: 54 start-page: 3068 year: 2006 end-page: 3070 ident: bib101 article-title: Antimalarial agents: closing the gate on toll-like receptors? publication-title: Arthritis Rheum. – volume: 66 start-page: 369 year: 2014 end-page: 378 ident: bib9 article-title: Population-based incidence and prevalence of systemic lupus erythematosus: the Michigan lupus epidemiology and surveillance program publication-title: Arthr. Rheumatol. – volume: 64 start-page: 37 year: 2011 end-page: 48 ident: bib248 article-title: Photoprotective effects of a broad-spectrum sunscreen in ultraviolet-induced cutaneous lupus erythematosus: a randomized, vehicle-controlled, double-blind study publication-title: J. Am. Acad. Dermatol. – volume: 19 start-page: 371 year: 1997 end-page: 379 ident: bib14 article-title: Echinacea-induced cytokine production by human macrophages publication-title: Int. J. Immunopharmacol. – volume: 2 start-page: 1 year: 1965 end-page: 28 ident: bib185 article-title: Diagnosis and treatment of systemic lupus erythematosus publication-title: Semin. Hematol. – volume: 83 start-page: 51 year: 2017 end-page: 61 ident: bib12 article-title: Lessons learned from twins in autoimmune and chronic inflammatory diseases publication-title: J. Autoimmun. – volume: 12 start-page: 367 year: 2016 end-page: 372 ident: bib224 article-title: The BAFFling effects of rituximab in lupus: danger ahead? publication-title: Nat. Rev. Rheumatol. – volume: 288 start-page: 2015 year: 2002 ident: bib256 article-title: Homocysteine and risk of ischemic heart disease and stroke publication-title: JAMA – volume: 6 start-page: 367 year: 2004 end-page: 374 ident: bib19 article-title: Occupational and environmental exposures as risk factors for systemic lupus erythematosus publication-title: Curr. Rheumatol. Rep. – volume: 3 start-page: 403 year: 2013 end-page: 428 ident: bib252 article-title: The influence of exercise on cognitive abilities publication-title: Compr. Physiol. – year: 2018 ident: bib192 article-title: Immunosuppressive treatment for proliferative lupus nephritis publication-title: Cochrane Database Syst. Rev. – volume: 91 start-page: 45 year: 2018 end-page: 54 ident: bib226 article-title: The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus publication-title: J. Autoimmun. – volume: 204 start-page: 1959 year: 2007 end-page: 1971 ident: bib231 article-title: BAFF and MyD88 signals promote a lupuslike disease independent of T cells publication-title: J. Exp. Med. – volume: 136 start-page: 699 year: 1997 end-page: 705 ident: bib56 article-title: Photosensitivity in lupus erythematosus, UV photoprovocation results compared with history of photosensitivity and clinical findings publication-title: Br. J. Dermatol. – volume: 16 start-page: 142 year: 2015 end-page: 152 ident: bib239 article-title: Pathophysiology of T follicular helper cells in humans and mice publication-title: Nat. Immunol. – volume: 82 start-page: 1 year: 2017 end-page: 12 ident: bib254 article-title: Cardiovascular disease in systemic lupus erythematosus: a comprehensive update publication-title: J. Autoimmun. – volume: 5 start-page: S4 year: 1996 end-page: S10 ident: bib103 article-title: Anti-malarial drugs: possible mechanisms of action in autoimmune disease and prospects for drug development publication-title: Lupus – volume: 23 start-page: 495 year: 2009 end-page: 506 ident: bib66 article-title: Lupus arthritis publication-title: Best Pract. Res. Clin. Rheumatol. – volume: 9 start-page: 241 year: 2000 end-page: 251 ident: bib214 article-title: Cyclosporine for lupus membranous nephritis: experience with ten patients and review of the literature publication-title: Lupus – volume: 66 start-page: 1168 year: 2007 end-page: 1172 ident: bib106 article-title: Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L) publication-title: Ann. Rheum. Dis. – volume: 25 start-page: 3939 year: 2010 end-page: 3948 ident: bib207 article-title: Long-term outcomes - mycophenolate mofetil treatment for lupus nephritis with addition of tacrolimus for resistant cases publication-title: Nephrol. Dial. Transplant. – volume: 66 start-page: 357 year: 2014 end-page: 368 ident: bib8 article-title: The incidence and prevalence of systemic lupus erythematosus, 2002-2004: the Georgia lupus registry publication-title: Arthr. Rheumatol. – volume: 10 start-page: 1 year: 2015 end-page: 16 ident: bib197 article-title: Tacrolimus protects podocytes from injury in lupus nephritis partly by stabilizing the cytoskeleton and inhibiting podocyte apoptosis publication-title: PloS One – volume: 148 start-page: 317 year: 2012 end-page: 322 ident: bib63 article-title: Impact of smoking in cutaneous lupus erythematosus publication-title: Arch. Dermatol. – volume: 75 start-page: 30 year: 2016 end-page: 36 ident: bib205 article-title: Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up publication-title: Ann. Rheum. Dis. – volume: 21 start-page: 944 year: 2012 end-page: 952 ident: bib211 article-title: Outcomes of maintenance therapy with tacrolimus versus azathioprine for active lupus nephritis: a multicenter randomized clinical trial publication-title: Lupus – volume: 5 year: 2018 ident: bib70 article-title: Measuring lupus arthritis activity using contrasted high-field MRI. Associations with clinical measures of disease activity and novel patterns of disease publication-title: Lupus Sci. Med. – volume: 36 start-page: 560 year: 2009 end-page: 564 ident: bib163 article-title: Prednisone, lupus activity, and permanent organ damage publication-title: J. Rheumatol. – volume: 65 start-page: 2143 year: 2013 end-page: 2153 ident: bib230 article-title: Baseline predictors of systemic lupus erythematosus flares: data from the combined placebo groups in the phase III belimumab trials publication-title: Arthritis Rheum. – volume: 13 start-page: 442 year: 2004 end-page: 449 ident: bib24 article-title: Pet dogs owned by lupus patients are at a higher risk of developing lupus publication-title: Lupus – volume: 22 start-page: 369 year: 2004 end-page: 377 ident: bib151 article-title: Adrenal androgens and the immune system publication-title: Semin. Reprod. Med. – volume: 53 start-page: 1 year: 2009 end-page: 16 ident: bib229 article-title: The BLyS family: toward a molecular understanding of B cell homeostasis publication-title: Cell Biochem. Biophys. – volume: 38 start-page: 551 year: 1995 end-page: 558 ident: bib2 article-title: The prevalence and incidence of systemic lupus erythematosus in Birmingham, England: relationship to ethnicity and country of birth publication-title: Arthritis Rheum. – volume: 24 year: 2014 ident: bib80 article-title: Anti-C1q antibodies in systemic lupus erythematosus publication-title: Lupus – volume: 46 start-page: 1840 year: 2002 end-page: 1850 ident: bib21 article-title: Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States publication-title: Arthritis Rheum. – volume: 48 start-page: 1616 year: 2009 end-page: 1618 ident: bib84 article-title: Lupus podocytopathy publication-title: Rheumatology – volume: 17 start-page: 135 year: 2016 end-page: 146 ident: bib54 article-title: Cutaneous lupus erythematosus: an update on pathogenesis, diagnosis and treatment publication-title: Am. J. Clin. Dermatol. – volume: 64 start-page: 1215 year: 2012 end-page: 1226 ident: bib221 article-title: LUNAR Investigator Group, Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study publication-title: Arthritis Rheum. – volume: 5 year: 2018 ident: bib242 article-title: S7A:8 Efficacy and safety of ustekinumab, an interleukin 12/23 inhibitor, in patients with active systemic lupus erythematosus: results of a phase 2, randomised placebo-controlled study publication-title: Lupus Sci. Med. – volume: 45 start-page: 217 year: 2013 end-page: 226 ident: bib138 article-title: The implication of vitamin D and autoimmunity: a comprehensive review publication-title: Clin. Rev. Allergy Immunol. – volume: 70 start-page: 732 year: 2006 end-page: 742 ident: bib176 article-title: Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial publication-title: Kidney Int. – volume: 166 start-page: 88 year: 2016 end-page: 101 ident: bib44 article-title: Digestion of chromatin in apoptotic cell microparticles prevents autoimmunity publication-title: Cell – volume: 27 start-page: 722 year: 2018 end-page: 727 ident: bib109 article-title: Effect of immunosuppressive therapies on survival of systemic lupus erythematosus: a propensity score analysis of a longitudinal cohort publication-title: Lupus – volume: 19 start-page: 1281 year: 2010 end-page: 1289 ident: bib202 article-title: Cyclosporine A or intravenous cyclophosphamide for lupus nephritis: the Cyclofa-Lune study publication-title: Lupus – volume: 48 start-page: 157 year: 2003 end-page: 165 ident: bib69 article-title: Jaccoud's arthropathy in systemic lupus erythematosus: differentiation of deforming and erosive patterns by magnetic resonance imaging publication-title: Arthritis Rheum. – volume: 12 start-page: 308 year: 2006 end-page: 318 ident: bib3 article-title: Epidemiology of systematic lupus erythematosus: a comparison of worldwide disease burden publication-title: Lupus – volume: 365 start-page: 1886 year: 2011 end-page: 1895 ident: bib178 article-title: Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis publication-title: N. Engl. J. Med. – volume: 96 start-page: 254 year: 1994 end-page: 259 ident: bib121 article-title: Effect of prednisone and hydroxychloroquine on coronary artery disease risk factors in systemic lupus erythematosus: a longitudinal data analysis publication-title: Am. J. Med. – volume: 16 start-page: 72 year: 2017 end-page: 80 ident: bib22 article-title: Mercury as an environmental stimulus in the development of autoimmunity – a systematic review publication-title: Autoimmun. Rev. – volume: 56 start-page: 924 year: 2007 end-page: 937 ident: bib177 article-title: Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis publication-title: Arthritis Rheum. – volume: 35 start-page: 1567 year: 2008 end-page: 1575 ident: bib154 article-title: Effects of prasterone on bone mineral density in women with active systemic lupus erythematosus receiving chronic glucocorticoid therapy publication-title: J. Rheumatol. – volume: 16 start-page: 847 year: 2002 end-page: 858 ident: bib1 article-title: Epidemiology of systemic lupus erythematosus publication-title: Best Pract. Res. Clin. Rheumatol. – volume: 64 start-page: 125 year: 2015 end-page: 136 ident: bib13 article-title: Immunogenetics of systemic lupus erythematosus: a comprehensive review publication-title: J. Autoimmun. – volume: 33 start-page: 57 year: 2006 end-page: 60 ident: bib165 article-title: Flares in Lupus: outcome Assessment Trial (FLOAT), a comparison between oral methylprednisolone and intramuscular triamcinolone publication-title: J. Rheumatol. – volume: 43 start-page: 215 year: 2017 end-page: 226 ident: bib182 article-title: Systemic lupus erythematosus and pregnancy publication-title: Rheum. Dis. Clin. N. Am. – year: 2017 ident: bib27 article-title: Etiology and Pathogenesis of Systemic Lupus Erythematosus – volume: 8 start-page: 1702 year: 2013 end-page: 1708 ident: bib79 article-title: Elevated subclinical double-stranded DNA antibodies and future proliferative lupus nephritis publication-title: Clin. J. Am. Soc. Nephrol. – volume: 42 start-page: 1050 year: 2003 end-page: 1054 ident: bib253 article-title: Fatigue in systemic lupus erythematosus: a randomized controlled trial of exercise publication-title: Rheumatology (Oxford) – volume: 44 start-page: 175 year: 2015 end-page: 185 ident: bib218 article-title: Efficacy and safety of rituximab in the treatment of non-renal systemic lupus erythematosus: a systematic review publication-title: Semin. Arthritis Rheum. – volume: 5 start-page: S16 year: 1996 end-page: S22 ident: bib102 article-title: Hydroxychloroquine use in the Baltimore Lupus Cohort: effects on lipids, glucose and thrombosis publication-title: Lupus – volume: 50 start-page: 849 year: 2004 end-page: 857 ident: bib17 article-title: Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis publication-title: Arthritis Rheum. – volume: 65 start-page: 2672 year: 2013 end-page: 2679 ident: bib225 article-title: Elevated serum BAFF levels are associated with rising anti-double-stranded DNA antibody levels and disease flare following B cell depletion therapy in systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 59 start-page: 1796 year: 2008 end-page: 1804 ident: bib187 article-title: Steroid-sparing effects of methotrexate in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial publication-title: Arthritis Rheum. – volume: 17 start-page: 352 year: 2012 end-page: 357 ident: bib213 article-title: Pilot 24 month study to compare mycophenolate mofetil and tacrolimus in the treatment of membranous lupus nephritis with nephrotic syndrome publication-title: Nephrology – volume: 69 year: 2017 ident: bib135 article-title: Kidney and skin single-cell RNA sequencing in lupus nephritis provides mechanistic insights and novel potential biomarkers publication-title: Arthr. Rheumatol. – volume: 71 start-page: 1502 year: 2012 end-page: 1509 ident: bib114 article-title: Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort study publication-title: Ann. Rheum. Dis. – volume: 9 year: 2018 ident: bib28 article-title: Aberrant T cell signaling and subsets in systemic lupus erythematosus publication-title: Front. Immunol. – volume: 15 start-page: 268 year: 2006 end-page: 275 ident: bib104 article-title: Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patients publication-title: Lupus – volume: 69 start-page: 2162 year: 2017 end-page: 2169 ident: bib26 article-title: Association of trauma and posttraumatic stress disorder with incident systemic lupus erythematosus in a longitudinal cohort of women publication-title: Arthr. Rheumatol. (Hoboken, N.J.). – volume: 21 start-page: 241 year: 2012 end-page: 250 ident: bib59 article-title: Environment and lupus-related diseases publication-title: Lupus – volume: 105 start-page: 5207 year: 2008 end-page: 5212 ident: bib133 article-title: The vitamin D receptor is required for iNKT cell development publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 199 start-page: 903 year: 2017 end-page: 910 ident: bib241 article-title: IL-23 limits the production of IL-2 and promotes autoimmunity in lupus publication-title: J. Immunol. – volume: 36 start-page: 82 year: 2009 end-page: 88 ident: bib249 article-title: Fibromyalgia, systemic lupus erythematosus (SLE), and evaluation of SLE activity publication-title: J. Rheumatol. – volume: 18 start-page: 822 year: 2009 end-page: 830 ident: bib116 article-title: Time to neuropsychiatric damage occurrence in LUMINA (LXVI): a multi-ethnic lupus cohort publication-title: Lupus – volume: 17 start-page: 91 year: 2008 end-page: 92 ident: bib247 article-title: Improving the prognosis of SLE without prescribing lupus drugs and the primary care paradox publication-title: Lupus – volume: 343 start-page: 1156 year: 2000 end-page: 1162 ident: bib189 article-title: Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis publication-title: N. Engl. J. Med. – volume: 282 start-page: 9358 year: 2007 end-page: 9363 ident: bib237 article-title: STAT3 regulates cytokine-mediated generation of inflammatory helper T cells publication-title: J. Biol. Chem. – volume: 34 start-page: 40 year: 2016 end-page: 47 ident: bib250 article-title: Fibromyalgia prevalence and related factors in a large registry of patients with systemic lupus erythematosus publication-title: Clin. Exp. Rheumatol. – reference: AstraZeneca, Update on TULIP 1 Phase III Trial for Anifrolumab in Systemic Lupus Erythematosus, (n.d.). – volume: 70 start-page: 266 year: 2018 end-page: 276 ident: bib246 article-title: Efficacy and safety of atacicept in patients with systemic lupus erythematosus: results of a twenty-four–week, multicenter, randomized, double-blind, placebo-controlled, parallel-arm, phase IIb study publication-title: Arthr. Rheumatol. – volume: 44 start-page: 1032 year: 2017 end-page: 1038 ident: bib112 article-title: Longterm hydroxychloroquine therapy and low-dose aspirin may have an additive effectiveness in the primary prevention of cardiovascular events in patients with systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 65 start-page: 1865 year: 2013 end-page: 1871 ident: bib143 article-title: Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein-to-creatinine ratio publication-title: Arthritis Rheum. – volume: 2 year: 2017 ident: bib269 article-title: Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis publication-title: JCI Insight – volume: 8 start-page: 456 year: 2009 end-page: 461 ident: bib39 article-title: Clinic and pathophysiology of photosensitivity in lupus erythematosus publication-title: Autoimmun. Rev. – volume: 69 start-page: 20 year: 2010 end-page: 28 ident: bib108 article-title: Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review publication-title: Ann. Rheum. Dis. – volume: 14 start-page: 2 year: 2005 end-page: 8 ident: bib188 article-title: Mechanisms of action of mycophenolate mofetil publication-title: Lupus – volume: 118 start-page: 415 year: 2011 end-page: 422 ident: bib130 article-title: American Academy of Ophthalmology, Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy publication-title: Ophthalmology – volume: 4 start-page: 377 year: 2005 end-page: 385 ident: bib152 article-title: Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders publication-title: Curr. Drug Targets Inflamm. Allergy – volume: 3 year: 2016 ident: bib264 article-title: Risk factors for osteoporosis and fragility fractures in patients with systemic lupus erythematosus publication-title: Lupus Sci. Med. – volume: 60 start-page: 3378 year: 2009 end-page: 3387 ident: bib90 article-title: Distinct subtypes of myelitis in systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 44 start-page: 1122 year: 2001 end-page: 1126 ident: bib20 article-title: Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure publication-title: Arthritis Rheum. – volume: 21 start-page: 84 year: 2018 end-page: 92 ident: bib120 article-title: Favorable effects of hydroxychloroquine on serum low density lipid in patients with systemic lupus erythematosus: a systematic review and meta-analysis publication-title: Int. J. Rheum. Dis. – volume: 67 start-page: 829 year: 2008 end-page: 834 ident: bib115 article-title: Seizures in patients with systemic lupus erythematosus: data from LUMINA, a multiethnic cohort (LUMINA LIV) publication-title: Ann. Rheum. Dis. – volume: 21 start-page: 736 year: 2012 end-page: 740 ident: bib141 article-title: Vitamin D and antiphospholipid syndrome publication-title: Lupus – volume: 267 start-page: 241 year: 1974 end-page: 242 ident: bib60 article-title: Lupus hair publication-title: Am. J. Med. Sci. – volume: 43 start-page: 1801 year: 2016 end-page: 1815 ident: bib160 article-title: Treatments for lupus nephritis: a systematic review and network metaanalysis publication-title: J. Rheumatol. – volume: 37 start-page: 2032 year: 2010 end-page: 2038 ident: bib72 article-title: Depression and cognitive impairment in newly diagnosed systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 64 start-page: 2677 year: 2012 end-page: 2686 ident: bib88 article-title: Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 42 start-page: 2026 year: 1999 end-page: 2038 ident: bib89 article-title: Neuroimaging in neuropsychiatric systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 39 start-page: 79 year: 2012 end-page: 85 ident: bib76 article-title: Frequency of class III and IV nephritis in systemic lupus erythematosus without clinical renal involvement: an analysis of predictive measures publication-title: J. Rheumatol. – volume: 5 start-page: 451 year: 1996 end-page: 455 ident: bib125 article-title: In vivo models of thrombosis for the antiphospholipid syndrome publication-title: Lupus – volume: 17 start-page: 233 year: 2017 end-page: 247 ident: bib155 article-title: Immune regulation by glucocorticoids publication-title: Nat. Rev. Immunol. – volume: 63 start-page: 243 year: 1984 end-page: 273 ident: bib262 article-title: Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency publication-title: Medicine (Baltimore) – volume: 21 start-page: 1457 year: 1994 end-page: 1462 ident: bib119 article-title: Comparison of hydroxychloroquine and placebo in the treatment of the arthropathy of mild systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 64 start-page: 797 year: 2012 end-page: 808 ident: bib156 article-title: American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis publication-title: Arthritis Care Res. – reference: . – volume: 25 start-page: 191 year: 1996 end-page: 193 ident: bib124 article-title: Thrombosis and systemic lupus erythematosus: the Hopkins Lupus Cohort perspective publication-title: Scand. J. Rheumatol. – volume: 69 start-page: 1155 year: 2010 end-page: 1157 ident: bib140 article-title: Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D? publication-title: Ann. Rheum. Dis. – volume: 19 year: 1992 ident: bib23 article-title: Anti-dsDNA antibodies in laboratory workers handling blood from patients with systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 21 start-page: 1178 year: 2012 end-page: 1182 ident: bib122 article-title: Hydroxychloroquine reduces low-density lipoprotein cholesterol levels in systemic lupus erythematosus: a longitudinal evaluation of the lipid-lowering effect publication-title: Lupus – volume: 69 start-page: 376 year: 2017 end-page: 386 ident: bib235 article-title: Anifrolumab, an anti–interferon-α receptor monoclonal antibody, in moderate-to-severe systemic lupus erythematosus publication-title: Arthr. Rheumatol. – volume: 186 start-page: 4794 year: 2011 end-page: 4804 ident: bib100 article-title: Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines publication-title: J. Immunol. – volume: 10 start-page: 365 year: 2009 end-page: 381 ident: bib55 article-title: Cutaneous lupus erythematosus: issues in diagnosis and treatment publication-title: Am. J. Clin. Dermatol. – volume: 303 start-page: 22 year: 1980 end-page: 24 ident: bib43 article-title: A genetic defect of the C1q subcomponent of complement associated with childhood (immune complex) nephritis publication-title: N. Engl. J. Med. – volume: 40 start-page: 1725 year: 1997 ident: bib47 article-title: Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 49 start-page: 723 year: 2010 end-page: 732 ident: bib180 article-title: The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE publication-title: Rheumatology (Oxford) – volume: 22 start-page: 1135 year: 2013 end-page: 1141 ident: bib208 article-title: Combined low-dose mycophenolate mofetil and tacrolimus for lupus nephritis with suboptimal response to standard therapy: a 12-month prospective study publication-title: Lupus – volume: 416 start-page: 603 year: 2002 end-page: 607 ident: bib98 article-title: Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors publication-title: Nature – volume: 1 start-page: 925 year: 2006 end-page: 932 ident: bib210 article-title: A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four years publication-title: Clin. J. Am. Soc. Nephrol. – volume: 36 start-page: 329 year: 2007 end-page: 337 ident: bib193 article-title: Mycophenolate mofetil for non-renal manifestations of systemic lupus erythematosus: a systematic review publication-title: Scand. J. Rheumatol. – volume: 11 start-page: 152 year: 2002 end-page: 160 ident: bib73 article-title: Systemic lupus erythematosus in three ethnic groups. XII. Risk factors for lupus nephritis after diagnosis publication-title: Lupus – volume: 774 start-page: 16 year: 1995 end-page: 28 ident: bib146 article-title: DHEA and peripheral androgen and estrogen formation: intracrinology publication-title: Ann. N. Y. Acad. Sci. – volume: 13 start-page: 731 year: 2012 end-page: 744 ident: bib219 article-title: Efficacy and safety of rituximab therapy for systemic lupus erythematosus: a systematic review and meta-analysis publication-title: J. Zhejiang Univ. Sci. B. – start-page: 1 year: 2018 end-page: 16 ident: bib243 article-title: Translational and clinical advances in JAK-STAT biology: the present and future of jakinibs publication-title: J. Leukoc. Biol. – volume: 76 start-page: 355 year: 1997 end-page: 368 ident: bib85 article-title: Renal vascular lesions in lupus nephritis publication-title: Medicine (Baltimore) – volume: 47 start-page: 920 year: 2008 end-page: 923 ident: bib137 article-title: Vitamin D deficiency in systemic lupus erythematosus: prevalence, predictors and clinical consequences publication-title: Rheumatology – volume: 179 start-page: 1317 year: 1994 end-page: 1330 ident: bib37 article-title: Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes publication-title: J. Exp. Med. – volume: 62 start-page: 222 year: 2010 end-page: 233 ident: bib220 article-title: Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial publication-title: Arthritis Rheum. – volume: 66 start-page: 470 year: 2007 end-page: 475 ident: bib170 article-title: Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system publication-title: Ann. Rheum. Dis. – volume: 353 start-page: 2219 year: 2005 end-page: 2228 ident: bib190 article-title: Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis publication-title: N. Engl. J. Med. – volume: 25 start-page: 873 year: 2016 end-page: 877 ident: bib82 article-title: Anti-C1q in systemic lupus erythematosus publication-title: Lupus – volume: 37 start-page: 57 year: 1994 end-page: 66 ident: bib18 article-title: Increased antiretroviral antibody reactivity in sera from a defined population of patients with systemic lupus erythematosus: correlation with autoantibodies and clinical manifestations publication-title: Arthritis Rheum. – volume: 99 start-page: 153 year: 1995 end-page: 163 ident: bib93 article-title: Neuropsychiatric lupus erythematosus: a 10-year prospective study on the value of diagnostic tests publication-title: Am. J. Med. – volume: 162 start-page: 18 year: 2015 end-page: 26 ident: bib209 article-title: Multitarget therapy for induction treatment of lupus nephritis: a randomized trial publication-title: Ann. Intern. Med. – volume: 77 year: 2018 ident: bib227 article-title: FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis publication-title: Ann. Rheum. Dis. – volume: 3 year: 2011 ident: bib34 article-title: Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA peptide complexes in systemic lupus erythematosus publication-title: Sci. Transl. Med. – volume: 76 year: 2017 ident: bib261 article-title: Homocysteine, antiphospholipid antibodies and risk of vascular events in patients with systemic lupus erythematosus [Abstract] publication-title: Ann. Rheum. Dis. – volume: 465 start-page: 937 year: 2010 end-page: 941 ident: bib40 article-title: TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus publication-title: Nature – volume: 12 start-page: 731 year: 2016 end-page: 742 ident: bib184 article-title: Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers publication-title: Nat. Rev. Rheumatol. – volume: 48 start-page: 2100 year: 2003 end-page: 2110 ident: bib147 article-title: Sex hormones and systemic lupus erythematosus: review and meta-analysis publication-title: Arthritis Rheum. – volume: 4 start-page: 176 year: 1995 end-page: 178 ident: bib4 article-title: Occasional series: lupus around the World frequency of lupus in people of African origin publication-title: Lupus – volume: 23 start-page: 69 year: 2014 end-page: 74 ident: bib203 article-title: Extended follow-up of the CYCLOFA-LUNE trial comparing two sequential induction and maintenance treatment regimens for proliferative lupus nephritis based either on cyclophosphamide or on cyclosporine A publication-title: Lupus – volume: 63 start-page: 1623 year: 2004 end-page: 1626 ident: bib150 article-title: Dehydroepiandrosterone suppresses interleukin 10 synthesis in women with systemic lupus erythematosus publication-title: Ann. Rheum. Dis. – volume: 14 start-page: 931 year: 2008 end-page: 938 ident: bib198 article-title: The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A publication-title: Nat. Med. – volume: 66 start-page: 2494 year: 2014 end-page: 2502 ident: bib7 article-title: Prevalence and incidence of systemic lupus erythematosus in a population-based registry of American Indian and Alaska Native people, 2007-2009 publication-title: Arthr. Rheumatol. – volume: 107 start-page: 9813 year: 2010 end-page: 9818 ident: bib35 article-title: Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 8 start-page: 80461 year: 2017 end-page: 80471 ident: bib128 article-title: Hydroxychloroquine and risk of cancer in patients with primary Sjögren syndrome: propensity score matched landmark analysis publication-title: Oncotarget – volume: 70 start-page: 571 year: 2018 end-page: 581 ident: bib49 article-title: Developing and refining new candidate criteria for systemic lupus erythematosus classification: an international collaboration publication-title: Arthritis Care Res. – volume: 74 start-page: 73 year: 2016 end-page: 84 ident: bib145 article-title: Immunomodulators in SLE: clinical evidence and immunologic actions publication-title: J. Autoimmun. – volume: 33 start-page: 1563 year: 2006 end-page: 1569 ident: bib75 article-title: Prognostic factors in lupus nephritis: diagnostic and therapeutic delay increases the risk of terminal renal failure publication-title: J. Rheumatol. – year: 2016 ident: bib53 article-title: Kelley and Firestein's Textbook of Rheumatology – volume: 51 start-page: 810 year: 2004 end-page: 818 ident: bib95 article-title: Reliability and validity of the proposed American College of Rheumatology neuropsychological battery for systemic lupus erythematosus publication-title: Arthritis Care Res. – volume: 18 start-page: 27 year: 1975 end-page: 34 ident: bib174 article-title: Long-term maintenance therapy with azathioprine in systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 20 start-page: 968 year: 2005 end-page: 973 ident: bib199 article-title: Efficacy and safety of tacrolimus compared with cyclosporin A microemulsion in renal transplantation: 2 year follow-up results publication-title: Nephrol. Dial. Transplant. – volume: 12 start-page: 716 year: 2016 end-page: 730 ident: bib11 article-title: New insights into the immunopathogenesis of systemic lupus erythematosus publication-title: Nat. Rev. Rheumatol. – volume: 319 start-page: 2388 year: 2018 end-page: 2400 ident: bib25 article-title: Association of stress-related disorders with subsequent autoimmune disease publication-title: Jama – volume: 61 start-page: 1339 year: 2002 end-page: 1350 ident: bib196 article-title: FK506 ameliorates proteinuria and glomerular lesions induced by anti-Thy 1.1 monoclonal antibody 1-22-3 publication-title: Kidney Int. – volume: 77 start-page: 937 year: 2016 end-page: 943 ident: bib240 article-title: Effect of IL6 and IL23 on double negative T cells and anti ds-DNA in systemic lupus erythematosus patients publication-title: Hum. Immunol. – volume: 348 start-page: 1120 year: 1996 end-page: 1124 ident: bib255 article-title: Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus publication-title: Lancet – volume: 69 start-page: 1521 year: 2017 end-page: 1537 ident: bib267 article-title: 2017 American college of rheumatology guideline for the prevention and treatment of glucocorticoid-induced osteoporosis publication-title: Arthr. Rheumatol. – volume: 70 year: 2018 ident: bib50 article-title: Validation of proposed EULAR/acr SLE classification criteria versus SLICC SLE classification criteria publication-title: Arthr. Rheumatol. – volume: 18 start-page: 1 year: 2016 end-page: 7 ident: bib45 article-title: Monogenic lupus publication-title: Curr. Rheumatol. Rep. – volume: 101 start-page: 1390 year: 2006 end-page: 1392 ident: bib183 article-title: Azathioprine use during pregnancy: unexpected intrauterine exposure to metabolites publication-title: Am. J. Gastroenterol. – volume: 23 start-page: 1156 year: 2015 end-page: 1163 ident: bib67 article-title: Anti-cyclic citrullinated peptide antibody as a marker of erosive arthritis in patients with systemic lupus erythematosus: a systematic review and meta-analysis publication-title: Lupus – volume: 34 start-page: 332 year: 2007 end-page: 335 ident: bib77 article-title: Renal biopsy in lupus patients with low levels of proteinuria publication-title: J. Rheumatol. – volume: 69 start-page: A2 year: 2017 ident: bib217 article-title: Treatment of active Lupus nephritis with Voclosporin: 48 week data from the aura-LV study publication-title: Am. J. Kidney Dis. Conf. Natl. Kidney Found. – volume: 75 start-page: 2091 year: 1985 end-page: 2093 ident: bib149 article-title: Prevention of autoantibody formation and prolonged survival in New Zealand Black/New Zealand White F1mice fed dehydroisoandrosterone publication-title: J. Clin. Invest. – volume: 35 start-page: 1776 year: 2008 end-page: 1781 ident: bib96 article-title: Cognitive function in a systemic lupus erythematosus inception cohort publication-title: J. Rheumatol. – volume: 83 start-page: 1203 year: 2016 end-page: 1212 ident: bib257 article-title: Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis publication-title: Mayo Clin. Proc. – volume: 20 start-page: 1267 year: 2011 end-page: 1274 ident: bib81 article-title: Anti-C1q antibodies have higher correlation with flares of lupus nephritis than other serum markers publication-title: Lupus – volume: 37 start-page: 2032 year: 2010 end-page: 2038 ident: bib97 article-title: Depression and cognitive impairment in newly diagnosed systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 363 start-page: 743 year: 2010 end-page: 754 ident: bib251 article-title: A randomized trial of tai chi for fibromyalgia publication-title: N. Engl. J. Med. – volume: 239 start-page: 460 year: 1992 end-page: 464 ident: bib91 article-title: Gadolinium-enhanced magnetic resonance imaging of the central nervous system in systemic lupus erythematosus publication-title: J. Neurol. – volume: 38 start-page: 810 year: 1995 end-page: 818 ident: bib92 article-title: Spin-spin relaxation of brain tissues in systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 31 start-page: 429 year: 2017 end-page: 438 ident: bib195 article-title: Calcineurin inhibitors in systemic lupus erythematosus publication-title: Best Pract. Res. Clin. Rheumatol. – volume: 5 start-page: 1 year: 2016 end-page: 13 ident: bib268 article-title: Calcium intake from diet and supplements and the risk of coronary artery calcification and its progression among older adults: 10-year follow-up of the multi-ethnic study of atherosclerosis (MESA) publication-title: J. Am. Heart Assoc. – volume: 324 start-page: 150 year: 1991 end-page: 154 ident: bib110 article-title: A randomized study of the effect of withdrawing hydroxychloroquine sulfate in systemic lupus erythematosus publication-title: N. Engl. J. Med. – volume: 189 start-page: 2689 year: 2012 end-page: 2695 ident: bib32 article-title: Neutrophil extracellular traps: double-edged swords of innate immunity publication-title: J. Immunol. – volume: 19 start-page: 935 year: 2010 end-page: 940 ident: bib206 article-title: Combination therapy of mycophenolate mofetil and tacrolimus in lupus nephritis publication-title: Lupus – volume: 68 start-page: 91 year: 2016 end-page: 98 ident: bib144 article-title: Vitamin D supplementation in adolescents and young adults with juvenile systemic lupus erythematosus for improvement in disease activity and fatigue scores: a randomized, double-blind, placebo-controlled trial publication-title: Arthritis Care Res. (Hoboken). – volume: 15 start-page: 93 year: 2016 end-page: 101 ident: bib204 article-title: Tacrolimus use in lupus nephritis: a systematic review and meta-analysis publication-title: Autoimmun. Rev. – volume: 7 start-page: 914 year: 2012 end-page: 925 ident: bib86 article-title: Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or Lupus-like disease publication-title: Clin. J. Am. Soc. Nephrol. – volume: 56 start-page: 4142 year: 2007 end-page: 4150 ident: bib245 article-title: Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial publication-title: Arthritis Rheum. – volume: 100 start-page: 2610 year: 2003 end-page: 2615 ident: bib29 article-title: Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 14 start-page: 529 year: 2005 end-page: 533 ident: bib266 article-title: High prevalence of vertebral deformity in premenopausal systemic lupus erythematosus patients publication-title: Lupus – volume: 111 start-page: 1133 year: 2003 end-page: 1145 ident: bib173 article-title: CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes publication-title: J. Clin. Invest. – volume: 39 start-page: 257 year: 2010 end-page: 268 ident: bib5 article-title: Understanding the epidemiology and progression of systemic lupus erythematosus publication-title: Semin. Arthritis Rheum. – volume: 11 start-page: 128 year: 2006 end-page: 150 ident: bib15 article-title: Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators publication-title: Altern. Med. Rev. – volume: 45 start-page: 86 year: 2001 end-page: 95 ident: bib58 article-title: Phototesting in lupus erythematosus: a 15-year experience publication-title: J. Am. Acad. Dermatol. – volume: 67 start-page: 1011 year: 2008 end-page: 1016 ident: bib223 article-title: B cell depletion therapy in systemic lupus erythematosus: relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response publication-title: Ann. Rheum. Dis. – volume: 76 start-page: 459 year: 2016 end-page: 483 ident: bib171 article-title: Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives publication-title: Drugs – volume: 64 start-page: 2677 year: 2012 end-page: 2686 ident: bib48 article-title: Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 17 start-page: 316 year: 2018 end-page: 322 ident: bib51 article-title: Performance of the 2012 Systemic Lupus International Collaborating Clinics classification criteria versus the 1997 American College of Rheumatology classification criteria in adult and juvenile systemic lupus erythematosus. A systematic review and meta-an publication-title: Autoimmun. Rev. – volume: 52 start-page: 1473 year: 2005 end-page: 1480 ident: bib111 article-title: Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual publication-title: Arthritis Rheum. – volume: 27 start-page: 262 year: 2007 end-page: 268 ident: bib259 article-title: Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats publication-title: Am. J. Nephrol. – volume: 93 start-page: 1624 year: 1996 end-page: 1629 ident: bib38 article-title: Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 72 start-page: 634 year: 2015 end-page: 639 ident: bib64 article-title: Influence of smoking on the efficacy of antimalarials in cutaneous lupus: a meta-analysis of the literature publication-title: J. Am. Acad. Dermatol. – volume: 62 start-page: 775 year: 2010 end-page: 784 ident: bib129 article-title: Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus publication-title: Arthritis Care Res. (Hoboken). – volume: 174 start-page: 357 year: 1986 end-page: 364 ident: bib94 article-title: Prevalence of cognitive impairment in systemic lupus erythematosus publication-title: J. Nerv. Ment. Dis. – volume: 64 start-page: 307 year: 2012 end-page: 313 ident: bib142 article-title: Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease publication-title: Reumatismo – volume: 23 start-page: 225 year: 2014 end-page: 235 ident: bib186 article-title: Methotrexate in systemic lupus erythematosus: a systematic review of its efficacy publication-title: Lupus – volume: 15 start-page: 366 year: 2006 end-page: 370 ident: bib113 article-title: Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis publication-title: Lupus – volume: 377 start-page: 721 year: 2011 end-page: 731 ident: bib233 article-title: Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial publication-title: Lancet – volume: 22 start-page: 1286 year: 2013 end-page: 1294 ident: bib263 article-title: Infection risk in systemic lupus erythematosus patients: susceptibility factors and preventive strategies publication-title: Lupus – volume: 25 start-page: 1271 year: 1982 end-page: 1277 ident: bib46 article-title: The 1982 revised criteria for the classification of systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 54 start-page: 2550 year: 2006 end-page: 2557 ident: bib74 article-title: Mortality in systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 72 start-page: 1280 year: 2013 end-page: 1286 ident: bib158 article-title: Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids publication-title: Ann. Rheum. Dis. – volume: 68 year: 2016 ident: bib159 article-title: Speed of remission with the use of voclosporin, MMF and low dose steroids: results of a global lupus nephritis study [abstract] publication-title: Arthr. Rheumatol. – volume: 65 start-page: e179 year: 2011 end-page: e193 ident: bib118 article-title: Cutaneous lupus erythematosus: update of therapeutic options: Part i publication-title: J. Am. Acad. Dermatol. – volume: 58 start-page: 2336 year: 2015 end-page: 2343 ident: bib123 article-title: Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial publication-title: Diabetologia – year: 2012 ident: bib52 article-title: Dubois' Lupus Erythematosus and Related Syndromes – volume: 149 start-page: 131 year: 2003 end-page: 137 ident: bib57 article-title: Photosensitivity in patients with lupus erythematosus: a clinical and photobiological study of 100 patients using a prolonged phototest protocol publication-title: Br. J. Dermatol. – volume: 3 year: 2011 ident: bib33 article-title: Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus publication-title: Sci. Transl. Med. – volume: 25 start-page: 2688 year: 2015 end-page: 2692 ident: bib68 article-title: Ultrasound evaluation of joints in systemic lupus erythematosus: a systematic review publication-title: Eur. Radiol. – volume: 46 start-page: 1820 year: 2002 end-page: 1829 ident: bib153 article-title: Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial publication-title: Arthritis Rheum. – volume: 30 start-page: 1955 year: 2003 end-page: 1959 ident: bib161 article-title: Accrual of organ damage over time in patients with systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 76 start-page: 1575 year: 2017 end-page: 1582 ident: bib181 article-title: Enteric-coated mycophenolate sodium versus azathioprine in patients with active systemic lupus erythematosus: a randomised clinical trial publication-title: Ann. Rheum. Dis. – volume: 20 start-page: 901 year: 2009 end-page: 911 ident: bib215 article-title: Randomized, controlled trial of prednisone, cyclophosphamide, and cyclosporine in lupus membranous nephropathy publication-title: J. Am. Soc. Nephrol. – volume: 318 start-page: 1423 year: 1988 end-page: 1431 ident: bib169 article-title: Clinical and immunologic effects of monthly administration of intravenous cyclophosphamide in severe systemic lupus erythematosus publication-title: N. Engl. J. Med. – volume: 8 start-page: 137 year: 1995 end-page: 145 ident: bib65 article-title: Musculoskeletal complications of systemic lupus erythematosus in the Hopkins Lupus Cohort: an update publication-title: Arthritis Care Res. – volume: 17 start-page: 205 year: 2015 ident: bib36 article-title: A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources publication-title: Arthritis Res. Ther. – volume: 69 start-page: 2083 year: 2010 end-page: 2089 ident: bib179 article-title: Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial publication-title: Ann. Rheum. Dis. – volume: 27 start-page: 1467 year: 2012 end-page: 1472 ident: bib200 article-title: Mycophenolate mofetil or tacrolimus compared with intravenous cyclophosphamide in the induction treatment for active lupus nephritis publication-title: Nephrol. Dial. Transplant. – volume: 17 start-page: 923 year: 1974 end-page: 937 ident: bib167 article-title: A double-blind controlled trial comparing cyclophosphamide, azathioprine and placebo in the treatment of lupus glomerulonephritis publication-title: Arthritis Rheum. – volume: 63 start-page: 3918 year: 2011 end-page: 3930 ident: bib232 article-title: A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 119 start-page: 3997 year: 2012 end-page: 4008 ident: bib238 article-title: Functional STAT3 deficiency compromises the generation of human T follicular helper cells publication-title: Blood – volume: 176 start-page: 708 year: 2012 end-page: 719 ident: bib162 article-title: Incidence of and risk factors for adverse cardiovascular events among patients with systemic lupus erythematosus publication-title: Am. J. Epidemiol. – volume: 115 start-page: 407 year: 2005 end-page: 417 ident: bib99 article-title: Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9 publication-title: J. Clin. Invest. – volume: 62 start-page: 211 year: 2010 end-page: 221 ident: bib194 article-title: Nonrenal disease activity following mycophenolate mofetil or intravenous cyclophosphamide as induction treatment for lupus nephritis: findings in a multicenter, prospective, randomized, open-label, parallel-group clinical trial publication-title: Arthritis Rheum. – volume: 43 start-page: 1503 year: 2016 end-page: 1509 ident: bib127 article-title: Risk of serious infection for patients with systemic lupus erythematosus starting glucocorticoids with or without antimalarials publication-title: J. Rheumatol. – volume: 123 start-page: 22 year: 2013 end-page: 25 ident: bib134 article-title: Antifibrotic vitamin D analogs – volume: 42 start-page: 147 year: 1994 end-page: 154 ident: bib212 article-title: Cyclosporine treatment of lupus membranous nephropathy publication-title: Clin. Nephrol. – volume: 30 start-page: 241 year: 1987 end-page: 248 ident: bib148 article-title: Low plasma androgens in women with systemic lupus erythematosus publication-title: Arthritis Rheum. – volume: 58 start-page: 1025 year: 2011 end-page: 1033 ident: bib258 article-title: Homocysteine and reclassification of cardiovascular disease risk publication-title: J. Am. Coll. Cardiol. – year: 2016 ident: bib166 article-title: Cytotoxic-immunosuppressive drug treatment publication-title: Syst. Lupus Erythematosus Basic, Appl. Clin. Asp. – volume: 211 start-page: 118 year: 2005 end-page: 122 ident: bib61 article-title: Association between discoid lupus erythematosus and cigarette smoking: a case-control study publication-title: Dermatology – volume: 65 start-page: 521 year: 2004 end-page: 530 ident: bib83 article-title: The classification of glomerulonephritis in systemic lupus erythematosus revisited publication-title: Kidney Int. – volume: 392 start-page: 222 year: 2018 end-page: 231 ident: bib244 article-title: Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 2 trial publication-title: Lancet – volume: 45 start-page: 419 year: 2001 end-page: 423 ident: bib87 article-title: Validity of the new American College of Rheumatology criteria for neuropsychiatric lupus syndromes: a population‐based evaluation publication-title: Arthritis Rheum. – volume: 2 start-page: 80 year: 2016 end-page: 87 ident: bib260 article-title: Homocysteine in renal injury publication-title: Kidney Dis. (Basel, Switzerland) – volume: 36 start-page: 82 year: 2008 end-page: 88 ident: bib71 article-title: Fibromyalgia, systemic lupus erythematosus (SLE), and evaluation of SLE activity publication-title: J. Rheumatol. – volume: 24 start-page: 669 year: 2015 end-page: 674 ident: bib62 article-title: Smoking is highly associated with discoid lupus erythematosus and lupus erythematosus tumidus: analysis of 405 patients publication-title: Lupus – volume: 127 start-page: 513 year: 1992 end-page: 518 ident: bib117 article-title: Treatment of cutaneous lupus erythematosus with acitretin and hydroxychloroquine publication-title: Br. J. Dermatol. – volume: 22 start-page: 422 year: 2015 end-page: 431 ident: bib265 article-title: Systemic lupus erythematosus, bone health, and osteoporosis publication-title: Curr. Opin. Endocrinol. Diabetes Obes. – volume: 31 start-page: 1053 year: 2016 end-page: 1057 ident: bib172 article-title: Con: cyclophosphamide for the treatment of lupus nephritis publication-title: Nephrol. Dial. Transplant. – volume: 314 start-page: 614 year: 1986 end-page: 619 ident: bib168 article-title: Therapy of lupus nephritis publication-title: N. Engl. J. Med. – volume: 523 start-page: 123 year: 2012 end-page: 133 ident: bib131 article-title: Where is the vitamin D receptor? publication-title: Arch. Biochem. Biophys. – volume: 43 start-page: 1801 year: 2000 end-page: 1808 ident: bib164 article-title: Damage in systemic lupus erythematosus and its association with corticosteroids publication-title: Arthritis Rheum. – volume: 20 start-page: 1103 year: 2009 end-page: 1112 ident: bib191 article-title: Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis publication-title: J. Am. Soc. Nephrol. – volume: 194 start-page: 4089 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib105 article-title: Cutting edge: antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase–DNA interaction publication-title: J. Immunol. doi: 10.4049/jimmunol.1402793 – volume: 65 start-page: e179 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib118 article-title: Cutaneous lupus erythematosus: update of therapeutic options: Part i publication-title: J. Am. Acad. Dermatol. doi: 10.1016/j.jaad.2010.06.018 – volume: 774 start-page: 16 year: 1995 ident: 10.1016/j.jaut.2018.11.001_bib146 article-title: DHEA and peripheral androgen and estrogen formation: intracrinology publication-title: Ann. N. Y. Acad. Sci. doi: 10.1111/j.1749-6632.1995.tb17369.x – volume: 22 start-page: 1135 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib208 article-title: Combined low-dose mycophenolate mofetil and tacrolimus for lupus nephritis with suboptimal response to standard therapy: a 12-month prospective study publication-title: Lupus doi: 10.1177/0961203313502864 – volume: 64 start-page: 2677 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib48 article-title: Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.34473 – volume: 2 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib269 article-title: Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis publication-title: JCI Insight doi: 10.1172/jci.insight.93009 – volume: 93 start-page: 1624 year: 1996 ident: 10.1016/j.jaut.2018.11.001_bib38 article-title: Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.93.4.1624 – volume: 33 start-page: 57 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib165 article-title: Flares in Lupus: outcome Assessment Trial (FLOAT), a comparison between oral methylprednisolone and intramuscular triamcinolone publication-title: J. Rheumatol. – volume: 43 start-page: 1503 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib127 article-title: Risk of serious infection for patients with systemic lupus erythematosus starting glucocorticoids with or without antimalarials publication-title: J. Rheumatol. doi: 10.3899/jrheum.150671 – volume: 69 start-page: 1521 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib267 article-title: 2017 American college of rheumatology guideline for the prevention and treatment of glucocorticoid-induced osteoporosis publication-title: Arthr. Rheumatol. doi: 10.1002/art.40137 – volume: 10 start-page: 778 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib42 article-title: The importance of natural IgM: scavenger, protector and regulator publication-title: Nat. Rev. Immunol. doi: 10.1038/nri2849 – volume: 64 start-page: 797 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib156 article-title: American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis publication-title: Arthritis Care Res. doi: 10.1002/acr.21664 – volume: 11 start-page: 152 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib73 article-title: Systemic lupus erythematosus in three ethnic groups. XII. Risk factors for lupus nephritis after diagnosis publication-title: Lupus doi: 10.1191/0961203302lu158oa – volume: 60 start-page: 3378 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib90 article-title: Distinct subtypes of myelitis in systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.24937 – volume: 3 start-page: 403 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib252 article-title: The influence of exercise on cognitive abilities publication-title: Compr. Physiol. doi: 10.1002/cphy.c110063 – volume: 43 start-page: 1801 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib160 article-title: Treatments for lupus nephritis: a systematic review and network metaanalysis publication-title: J. Rheumatol. doi: 10.3899/jrheum.160041 – volume: 10 start-page: 365 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib55 article-title: Cutaneous lupus erythematosus: issues in diagnosis and treatment publication-title: Am. J. Clin. Dermatol. doi: 10.2165/11310780-000000000-00000 – volume: 54 start-page: 3068 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib101 article-title: Antimalarial agents: closing the gate on toll-like receptors? publication-title: Arthritis Rheum. doi: 10.1002/art.22157 – volume: 66 start-page: 1168 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib106 article-title: Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L) publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2006.068676 – volume: 319 start-page: 2388 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib25 article-title: Association of stress-related disorders with subsequent autoimmune disease publication-title: Jama doi: 10.1001/jama.2018.7028 – volume: 23 start-page: 1156 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib67 article-title: Anti-cyclic citrullinated peptide antibody as a marker of erosive arthritis in patients with systemic lupus erythematosus: a systematic review and meta-analysis publication-title: Lupus doi: 10.1177/0961203314540967 – volume: 40 start-page: 1725 year: 1997 ident: 10.1016/j.jaut.2018.11.001_bib47 article-title: Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.1780400928 – volume: 10 start-page: 1 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib197 article-title: Tacrolimus protects podocytes from injury in lupus nephritis partly by stabilizing the cytoskeleton and inhibiting podocyte apoptosis publication-title: PloS One doi: 10.1371/journal.pone.0132724 – volume: 69 start-page: A2 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib217 article-title: Treatment of active Lupus nephritis with Voclosporin: 48 week data from the aura-LV study publication-title: Am. J. Kidney Dis. Conf. Natl. Kidney Found. doi: 10.1053/j.ajkd.2017.03.008 – volume: 25 start-page: 873 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib82 article-title: Anti-C1q in systemic lupus erythematosus publication-title: Lupus doi: 10.1177/0961203316645205 – volume: 523 start-page: 123 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib131 article-title: Where is the vitamin D receptor? publication-title: Arch. Biochem. Biophys. doi: 10.1016/j.abb.2012.04.001 – volume: 8 start-page: 137 year: 1995 ident: 10.1016/j.jaut.2018.11.001_bib65 article-title: Musculoskeletal complications of systemic lupus erythematosus in the Hopkins Lupus Cohort: an update publication-title: Arthritis Care Res. doi: 10.1002/art.1790080305 – volume: 47 start-page: 920 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib137 article-title: Vitamin D deficiency in systemic lupus erythematosus: prevalence, predictors and clinical consequences publication-title: Rheumatology doi: 10.1093/rheumatology/ken121 – volume: 27 start-page: 722 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib109 article-title: Effect of immunosuppressive therapies on survival of systemic lupus erythematosus: a propensity score analysis of a longitudinal cohort publication-title: Lupus doi: 10.1177/0961203317739129 – volume: 70 start-page: 732 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib176 article-title: Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial publication-title: Kidney Int. doi: 10.1038/sj.ki.5001630 – volume: 66 start-page: 2494 year: 2014 ident: 10.1016/j.jaut.2018.11.001_bib7 article-title: Prevalence and incidence of systemic lupus erythematosus in a population-based registry of American Indian and Alaska Native people, 2007-2009 publication-title: Arthr. Rheumatol. doi: 10.1002/art.38720 – volume: 1 start-page: 925 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib210 article-title: A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four years publication-title: Clin. J. Am. Soc. Nephrol. doi: 10.2215/CJN.02271205 – volume: 62 start-page: 222 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib220 article-title: Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial publication-title: Arthritis Rheum. doi: 10.1002/art.27233 – volume: 17 start-page: 233 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib155 article-title: Immune regulation by glucocorticoids publication-title: Nat. Rev. Immunol. doi: 10.1038/nri.2017.1 – volume: 392 start-page: 222 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib244 article-title: Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 2 trial publication-title: Lancet doi: 10.1016/S0140-6736(18)31363-1 – volume: 119 start-page: 3997 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib238 article-title: Functional STAT3 deficiency compromises the generation of human T follicular helper cells publication-title: Blood doi: 10.1182/blood-2011-11-392985 – volume: 77 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib227 article-title: FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis publication-title: Ann. Rheum. Dis. – volume: 46 start-page: 1820 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib153 article-title: Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial publication-title: Arthritis Rheum. doi: 10.1002/art.10364 – volume: 65 start-page: 2672 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib225 article-title: Elevated serum BAFF levels are associated with rising anti-double-stranded DNA antibody levels and disease flare following B cell depletion therapy in systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.38074 – volume: 107 start-page: 9813 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib35 article-title: Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0909927107 – volume: 14 start-page: 931 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib198 article-title: The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A publication-title: Nat. Med. doi: 10.1038/nm.1857 – volume: 45 start-page: 419 year: 2001 ident: 10.1016/j.jaut.2018.11.001_bib87 article-title: Validity of the new American College of Rheumatology criteria for neuropsychiatric lupus syndromes: a population‐based evaluation publication-title: Arthritis Rheum. doi: 10.1002/1529-0131(200110)45:5<419::AID-ART360>3.0.CO;2-X – volume: 19 year: 1992 ident: 10.1016/j.jaut.2018.11.001_bib23 article-title: Anti-dsDNA antibodies in laboratory workers handling blood from patients with systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 101 start-page: 1390 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib183 article-title: Azathioprine use during pregnancy: unexpected intrauterine exposure to metabolites publication-title: Am. J. Gastroenterol. doi: 10.1111/j.1572-0241.2006.00538.x – volume: 62 start-page: 211 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib194 article-title: Nonrenal disease activity following mycophenolate mofetil or intravenous cyclophosphamide as induction treatment for lupus nephritis: findings in a multicenter, prospective, randomized, open-label, parallel-group clinical trial publication-title: Arthritis Rheum. doi: 10.1002/art.25052 – volume: 64 start-page: 307 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib142 article-title: Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease publication-title: Reumatismo doi: 10.4081/reumatismo.2012.307 – volume: 111 start-page: 1133 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib173 article-title: CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes publication-title: J. Clin. Invest. doi: 10.1172/JCI16432 – volume: 21 start-page: 1457 year: 1994 ident: 10.1016/j.jaut.2018.11.001_bib119 article-title: Comparison of hydroxychloroquine and placebo in the treatment of the arthropathy of mild systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 70 start-page: 266 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib246 article-title: Efficacy and safety of atacicept in patients with systemic lupus erythematosus: results of a twenty-four–week, multicenter, randomized, double-blind, placebo-controlled, parallel-arm, phase IIb study publication-title: Arthr. Rheumatol. doi: 10.1002/art.40360 – volume: 62 start-page: 775 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib129 article-title: Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus publication-title: Arthritis Care Res. (Hoboken). doi: 10.1002/acr.20133 – volume: 13 start-page: 731 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib219 article-title: Efficacy and safety of rituximab therapy for systemic lupus erythematosus: a systematic review and meta-analysis publication-title: J. Zhejiang Univ. Sci. B. doi: 10.1631/jzus.B1200057 – volume: 136 start-page: 699 year: 1997 ident: 10.1016/j.jaut.2018.11.001_bib56 article-title: Photosensitivity in lupus erythematosus, UV photoprovocation results compared with history of photosensitivity and clinical findings publication-title: Br. J. Dermatol. doi: 10.1111/j.1365-2133.1997.tb03655.x – volume: 9 start-page: 491 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib228 article-title: Cracking the BAFF code publication-title: Nat. Rev. Immunol. doi: 10.1038/nri2572 – volume: 65 start-page: 521 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib83 article-title: The classification of glomerulonephritis in systemic lupus erythematosus revisited publication-title: Kidney Int. doi: 10.1111/j.1523-1755.2004.00443.x – volume: 21 start-page: 944 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib211 article-title: Outcomes of maintenance therapy with tacrolimus versus azathioprine for active lupus nephritis: a multicenter randomized clinical trial publication-title: Lupus doi: 10.1177/0961203312442259 – volume: 38 start-page: 551 year: 1995 ident: 10.1016/j.jaut.2018.11.001_bib2 article-title: The prevalence and incidence of systemic lupus erythematosus in Birmingham, England: relationship to ethnicity and country of birth publication-title: Arthritis Rheum. doi: 10.1002/art.1780380415 – volume: 149 start-page: 131 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib57 article-title: Photosensitivity in patients with lupus erythematosus: a clinical and photobiological study of 100 patients using a prolonged phototest protocol publication-title: Br. J. Dermatol. doi: 10.1046/j.1365-2133.2003.05379.x – volume: 324 start-page: 23 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib132 article-title: Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.107.127209 – volume: 66 start-page: 357 year: 2014 ident: 10.1016/j.jaut.2018.11.001_bib8 article-title: The incidence and prevalence of systemic lupus erythematosus, 2002-2004: the Georgia lupus registry publication-title: Arthr. Rheumatol. doi: 10.1002/art.38239 – volume: 25 start-page: 1271 year: 1982 ident: 10.1016/j.jaut.2018.11.001_bib46 article-title: The 1982 revised criteria for the classification of systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.1780251101 – volume: 30 start-page: 241 year: 1987 ident: 10.1016/j.jaut.2018.11.001_bib148 article-title: Low plasma androgens in women with systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.1780300301 – start-page: 1 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib243 article-title: Translational and clinical advances in JAK-STAT biology: the present and future of jakinibs publication-title: J. Leukoc. Biol. – volume: 51 start-page: 810 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib95 article-title: Reliability and validity of the proposed American College of Rheumatology neuropsychological battery for systemic lupus erythematosus publication-title: Arthritis Care Res. doi: 10.1002/art.20692 – volume: 69 start-page: 1155 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib140 article-title: Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D? publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2009.120329 – volume: 17 start-page: 205 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib36 article-title: A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources publication-title: Arthritis Res. Ther. doi: 10.1186/s13075-015-0726-y – volume: 56 start-page: 924 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib177 article-title: Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis publication-title: Arthritis Rheum. doi: 10.1002/art.22449 – volume: 23 start-page: 225 issue: 3 year: 2014 ident: 10.1016/j.jaut.2018.11.001_bib186 article-title: Methotrexate in systemic lupus erythematosus: a systematic review of its efficacy publication-title: Lupus doi: 10.1177/0961203313519159 – volume: 64 start-page: 125 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib13 article-title: Immunogenetics of systemic lupus erythematosus: a comprehensive review publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2015.08.004 – volume: 12 start-page: 731 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib184 article-title: Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers publication-title: Nat. Rev. Rheumatol. doi: 10.1038/nrrheum.2016.175 – volume: 12 start-page: 308 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib3 article-title: Epidemiology of systematic lupus erythematosus: a comparison of worldwide disease burden publication-title: Lupus doi: 10.1191/0961203306lu2305xx – volume: 166 start-page: 88 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib44 article-title: Digestion of chromatin in apoptotic cell microparticles prevents autoimmunity publication-title: Cell doi: 10.1016/j.cell.2016.05.034 – volume: 100 start-page: 2610 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib29 article-title: Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0337679100 – volume: 148 start-page: 317 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib63 article-title: Impact of smoking in cutaneous lupus erythematosus publication-title: Arch. Dermatol. doi: 10.1001/archdermatol.2011.342 – volume: 15 start-page: 268 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib104 article-title: Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patients publication-title: Lupus doi: 10.1191/0961203306lu2299oa – volume: 17 start-page: 923 year: 1974 ident: 10.1016/j.jaut.2018.11.001_bib167 article-title: A double-blind controlled trial comparing cyclophosphamide, azathioprine and placebo in the treatment of lupus glomerulonephritis publication-title: Arthritis Rheum. doi: 10.1002/art.1780170602 – volume: 36 start-page: 560 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib163 article-title: Prednisone, lupus activity, and permanent organ damage publication-title: J. Rheumatol. doi: 10.3899/jrheum.080828 – volume: 17 start-page: 91 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib247 article-title: Improving the prognosis of SLE without prescribing lupus drugs and the primary care paradox publication-title: Lupus doi: 10.1177/0961203307086267 – volume: 211 start-page: 118 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib61 article-title: Association between discoid lupus erythematosus and cigarette smoking: a case-control study publication-title: Dermatology doi: 10.1159/000086440 – volume: 6 start-page: 367 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib19 article-title: Occupational and environmental exposures as risk factors for systemic lupus erythematosus publication-title: Curr. Rheumatol. Rep. doi: 10.1007/s11926-004-0011-6 – volume: 42 start-page: 147 year: 1994 ident: 10.1016/j.jaut.2018.11.001_bib212 article-title: Cyclosporine treatment of lupus membranous nephropathy publication-title: Clin. Nephrol. – volume: 46 start-page: 1840 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib21 article-title: Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States publication-title: Arthritis Rheum. doi: 10.1002/art.10368 – volume: 282 start-page: 9358 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib237 article-title: STAT3 regulates cytokine-mediated generation of inflammatory helper T cells publication-title: J. Biol. Chem. doi: 10.1074/jbc.C600321200 – volume: 24 year: 2014 ident: 10.1016/j.jaut.2018.11.001_bib80 article-title: Anti-C1q antibodies in systemic lupus erythematosus publication-title: Lupus – volume: 96 start-page: 254 year: 1994 ident: 10.1016/j.jaut.2018.11.001_bib121 article-title: Effect of prednisone and hydroxychloroquine on coronary artery disease risk factors in systemic lupus erythematosus: a longitudinal data analysis publication-title: Am. J. Med. doi: 10.1016/0002-9343(94)90151-1 – volume: 353 start-page: 2219 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib190 article-title: Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa043731 – volume: 9 start-page: 241 year: 2000 ident: 10.1016/j.jaut.2018.11.001_bib214 article-title: Cyclosporine for lupus membranous nephritis: experience with ten patients and review of the literature publication-title: Lupus doi: 10.1191/096120300680198935 – volume: 71 start-page: 1343 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib234 article-title: Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2011-200937 – volume: 27 start-page: 262 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib259 article-title: Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats publication-title: Am. J. Nephrol. doi: 10.1159/000101471 – volume: 57 start-page: 235 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib201 article-title: Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: a multicenter randomized clinical trial publication-title: Am. J. Kidney Dis. doi: 10.1053/j.ajkd.2010.08.036 – volume: 65 start-page: 1500 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib6 article-title: Ethnicity and mortality from systemic lupus erythematosus in the US publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2005.040907 – volume: 11 start-page: 128 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib15 article-title: Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators publication-title: Altern. Med. Rev. – volume: 8 start-page: 80461 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib128 article-title: Hydroxychloroquine and risk of cancer in patients with primary Sjögren syndrome: propensity score matched landmark analysis publication-title: Oncotarget doi: 10.18632/oncotarget.19057 – volume: 58 start-page: 15 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib10 article-title: Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I publication-title: Arthritis Rheum. doi: 10.1002/art.23177 – volume: 3 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib33 article-title: Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.3001201 – volume: 22 start-page: 369 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib151 article-title: Adrenal androgens and the immune system publication-title: Semin. Reprod. Med. doi: 10.1055/s-2004-861553 – volume: 39 start-page: 79 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib76 article-title: Frequency of class III and IV nephritis in systemic lupus erythematosus without clinical renal involvement: an analysis of predictive measures publication-title: J. Rheumatol. doi: 10.3899/jrheum.110532 – volume: 69 start-page: 20 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib108 article-title: Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2008.101766 – volume: 91 start-page: 45 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib226 article-title: The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2018.03.003 – volume: 69 start-page: 376 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib235 article-title: Anifrolumab, an anti–interferon-α receptor monoclonal antibody, in moderate-to-severe systemic lupus erythematosus publication-title: Arthr. Rheumatol. doi: 10.1002/art.39962 – volume: 5 start-page: 1 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib268 article-title: Calcium intake from diet and supplements and the risk of coronary artery calcification and its progression among older adults: 10-year follow-up of the multi-ethnic study of atherosclerosis (MESA) publication-title: J. Am. Heart Assoc. doi: 10.1161/JAHA.116.003815 – volume: 15 start-page: 577 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib107 article-title: Effect of antimalarials on thrombosis and survival in patients with systemic lupus erythematosus publication-title: Lupus doi: 10.1177/0961203306071872 – volume: 36 start-page: 82 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib71 article-title: Fibromyalgia, systemic lupus erythematosus (SLE), and evaluation of SLE activity publication-title: J. Rheumatol. doi: 10.3899/jrheum.080212 – volume: 49 start-page: 723 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib180 article-title: The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/kep396 – volume: 20 start-page: 1 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib222 article-title: A perspective on B-cell-targeting therapy for SLE publication-title: Mod. Rheumatol. doi: 10.3109/s10165-009-0213-x – volume: 38 start-page: 810 year: 1995 ident: 10.1016/j.jaut.2018.11.001_bib92 article-title: Spin-spin relaxation of brain tissues in systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.1780380615 – volume: 348 start-page: 1120 year: 1996 ident: 10.1016/j.jaut.2018.11.001_bib255 article-title: Plasma homocysteine as a risk factor for atherothrombotic events in systemic lupus erythematosus publication-title: Lancet doi: 10.1016/S0140-6736(96)03032-2 – volume: 33 start-page: 1563 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib75 article-title: Prognostic factors in lupus nephritis: diagnostic and therapeutic delay increases the risk of terminal renal failure publication-title: J. Rheumatol. – volume: 465 start-page: 937 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib40 article-title: TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus publication-title: Nature doi: 10.1038/nature09102 – volume: 83 start-page: 1203 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib257 article-title: Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis publication-title: Mayo Clin. Proc. doi: 10.4065/83.11.1203 – volume: 99 start-page: 153 year: 1995 ident: 10.1016/j.jaut.2018.11.001_bib93 article-title: Neuropsychiatric lupus erythematosus: a 10-year prospective study on the value of diagnostic tests publication-title: Am. J. Med. doi: 10.1016/S0002-9343(99)80135-1 – volume: 50 start-page: 3958 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib31 article-title: Coordinate overexpression of interferon-?-induced genes in systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.20798 – ident: 10.1016/j.jaut.2018.11.001_bib236 – volume: 67 start-page: 829 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib115 article-title: Seizures in patients with systemic lupus erythematosus: data from LUMINA, a multiethnic cohort (LUMINA LIV) publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2007.077594 – volume: 12 start-page: 716 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib11 article-title: New insights into the immunopathogenesis of systemic lupus erythematosus publication-title: Nat. Rev. Rheumatol. doi: 10.1038/nrrheum.2016.186 – year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib52 – volume: 18 start-page: 27 year: 1975 ident: 10.1016/j.jaut.2018.11.001_bib174 article-title: Long-term maintenance therapy with azathioprine in systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.1780180106 – volume: 20 start-page: 968 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib199 article-title: Efficacy and safety of tacrolimus compared with cyclosporin A microemulsion in renal transplantation: 2 year follow-up results publication-title: Nephrol. Dial. Transplant. doi: 10.1093/ndt/gfh739 – volume: 204 start-page: 1959 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib231 article-title: BAFF and MyD88 signals promote a lupuslike disease independent of T cells publication-title: J. Exp. Med. doi: 10.1084/jem.20062567 – volume: 363 start-page: 743 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib251 article-title: A randomized trial of tai chi for fibromyalgia publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa0912611 – volume: 37 start-page: 2032 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib72 article-title: Depression and cognitive impairment in newly diagnosed systemic lupus erythematosus publication-title: J. Rheumatol. doi: 10.3899/jrheum.091366 – volume: 11 start-page: 2675 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib216 article-title: The PROMISE study: a phase 2b multicenter study of voclosporin (ISA247) versus tacrolimus in de Novo kidney transplantation publication-title: Am. J. Transplant. doi: 10.1111/j.1600-6143.2011.03763.x – volume: 179 start-page: 1317 year: 1994 ident: 10.1016/j.jaut.2018.11.001_bib37 article-title: Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes publication-title: J. Exp. Med. doi: 10.1084/jem.179.4.1317 – volume: 12 start-page: 367 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib224 article-title: The BAFFling effects of rituximab in lupus: danger ahead? publication-title: Nat. Rev. Rheumatol. doi: 10.1038/nrrheum.2016.18 – volume: 288 start-page: 2015 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib256 article-title: Homocysteine and risk of ischemic heart disease and stroke publication-title: JAMA doi: 10.1001/jama.288.16.2015 – volume: 9 start-page: 453 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib139 article-title: Vitamin D and systemic lupus erythematosus: an update publication-title: Expert Rev. Clin. Immunol. doi: 10.1586/eci.13.19 – volume: 343 start-page: 1156 year: 2000 ident: 10.1016/j.jaut.2018.11.001_bib189 article-title: Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis publication-title: N. Engl. J. Med. doi: 10.1056/NEJM200010193431604 – volume: 15 start-page: 93 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib204 article-title: Tacrolimus use in lupus nephritis: a systematic review and meta-analysis publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2015.09.006 – volume: 17 start-page: 135 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib54 article-title: Cutaneous lupus erythematosus: an update on pathogenesis, diagnosis and treatment publication-title: Am. J. Clin. Dermatol. doi: 10.1007/s40257-016-0173-9 – volume: 377 start-page: 721 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib233 article-title: Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial publication-title: Lancet doi: 10.1016/S0140-6736(10)61354-2 – volume: 63 start-page: 243 year: 1984 ident: 10.1016/j.jaut.2018.11.001_bib262 article-title: Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency publication-title: Medicine (Baltimore) doi: 10.1097/00005792-198409000-00001 – volume: 76 start-page: 1575 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib181 article-title: Enteric-coated mycophenolate sodium versus azathioprine in patients with active systemic lupus erythematosus: a randomised clinical trial publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2016-210882 – volume: 44 start-page: 1032 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib112 article-title: Longterm hydroxychloroquine therapy and low-dose aspirin may have an additive effectiveness in the primary prevention of cardiovascular events in patients with systemic lupus erythematosus publication-title: J. Rheumatol. doi: 10.3899/jrheum.161351 – volume: 16 start-page: 847 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib1 article-title: Epidemiology of systemic lupus erythematosus publication-title: Best Pract. Res. Clin. Rheumatol. doi: 10.1053/berh.2002.0259 – volume: 20 start-page: 901 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib215 article-title: Randomized, controlled trial of prednisone, cyclophosphamide, and cyclosporine in lupus membranous nephropathy publication-title: J. Am. Soc. Nephrol. doi: 10.1681/ASN.2008060665 – volume: 197 start-page: 711 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib30 article-title: Interferon and granulopoiesis signatures in systemic lupus erythematosus blood publication-title: J. Exp. Med. doi: 10.1084/jem.20021553 – volume: 18 start-page: 822 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib116 article-title: Time to neuropsychiatric damage occurrence in LUMINA (LXVI): a multi-ethnic lupus cohort publication-title: Lupus doi: 10.1177/0961203309104392 – volume: 13 start-page: 442 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib24 article-title: Pet dogs owned by lupus patients are at a higher risk of developing lupus publication-title: Lupus doi: 10.1191/0961203303lu1039oa – volume: 5 start-page: S16 issue: Suppl 1 year: 1996 ident: 10.1016/j.jaut.2018.11.001_bib102 article-title: Hydroxychloroquine use in the Baltimore Lupus Cohort: effects on lipids, glucose and thrombosis publication-title: Lupus doi: 10.1177/0961203396005001051 – volume: 5 start-page: S4 issue: Suppl 1 year: 1996 ident: 10.1016/j.jaut.2018.11.001_bib103 article-title: Anti-malarial drugs: possible mechanisms of action in autoimmune disease and prospects for drug development publication-title: Lupus doi: 10.1177/0961203396005001031 – volume: 53 start-page: 1 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib229 article-title: The BLyS family: toward a molecular understanding of B cell homeostasis publication-title: Cell Biochem. Biophys. doi: 10.1007/s12013-008-9036-1 – volume: 75 start-page: 2091 year: 1985 ident: 10.1016/j.jaut.2018.11.001_bib149 article-title: Prevention of autoantibody formation and prolonged survival in New Zealand Black/New Zealand White F1mice fed dehydroisoandrosterone publication-title: J. Clin. Invest. doi: 10.1172/JCI111929 – volume: 15 start-page: 366 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib113 article-title: Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis publication-title: Lupus doi: 10.1191/0961203306lu2313oa – volume: 19 start-page: 935 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib206 article-title: Combination therapy of mycophenolate mofetil and tacrolimus in lupus nephritis publication-title: Lupus doi: 10.1177/0961203310365714 – volume: 67 start-page: 1011 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib223 article-title: B cell depletion therapy in systemic lupus erythematosus: relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2007.079418 – volume: 21 start-page: 736 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib141 article-title: Vitamin D and antiphospholipid syndrome publication-title: Lupus doi: 10.1177/0961203312446386 – volume: 63 start-page: 3918 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib232 article-title: A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.30613 – volume: 17 start-page: 316 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib51 article-title: Performance of the 2012 Systemic Lupus International Collaborating Clinics classification criteria versus the 1997 American College of Rheumatology classification criteria in adult and juvenile systemic lupus erythematosus. A systematic review and meta-an publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2018.01.007 – volume: 37 start-page: 2032 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib97 article-title: Depression and cognitive impairment in newly diagnosed systemic lupus erythematosus publication-title: J. Rheumatol. doi: 10.3899/jrheum.091366 – volume: 66 start-page: 369 year: 2014 ident: 10.1016/j.jaut.2018.11.001_bib9 article-title: Population-based incidence and prevalence of systemic lupus erythematosus: the Michigan lupus epidemiology and surveillance program publication-title: Arthr. Rheumatol. doi: 10.1002/art.38238 – volume: 43 start-page: 215 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib182 article-title: Systemic lupus erythematosus and pregnancy publication-title: Rheum. Dis. Clin. N. Am. doi: 10.1016/j.rdc.2016.12.009 – volume: 19 start-page: 1281 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib202 article-title: Cyclosporine A or intravenous cyclophosphamide for lupus nephritis: the Cyclofa-Lune study publication-title: Lupus doi: 10.1177/0961203310371155 – volume: 239 start-page: 460 year: 1992 ident: 10.1016/j.jaut.2018.11.001_bib91 article-title: Gadolinium-enhanced magnetic resonance imaging of the central nervous system in systemic lupus erythematosus publication-title: J. Neurol. doi: 10.1007/BF00856812 – volume: 74 start-page: 73 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib145 article-title: Immunomodulators in SLE: clinical evidence and immunologic actions publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2016.06.010 – volume: 416 start-page: 603 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib98 article-title: Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors publication-title: Nature doi: 10.1038/416603a – volume: 64 start-page: 1215 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib221 article-title: LUNAR Investigator Group, Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study publication-title: Arthritis Rheum. doi: 10.1002/art.34359 – volume: 318 start-page: 1423 year: 1988 ident: 10.1016/j.jaut.2018.11.001_bib169 article-title: Clinical and immunologic effects of monthly administration of intravenous cyclophosphamide in severe systemic lupus erythematosus publication-title: N. Engl. J. Med. doi: 10.1056/NEJM198806023182203 – volume: 64 start-page: 2677 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib88 article-title: Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.34473 – volume: 69 start-page: 2162 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib26 article-title: Association of trauma and posttraumatic stress disorder with incident systemic lupus erythematosus in a longitudinal cohort of women publication-title: Arthr. Rheumatol. (Hoboken, N.J.). doi: 10.1002/art.40222 – volume: 303 start-page: 22 year: 1980 ident: 10.1016/j.jaut.2018.11.001_bib43 article-title: A genetic defect of the C1q subcomponent of complement associated with childhood (immune complex) nephritis publication-title: N. Engl. J. Med. doi: 10.1056/NEJM198007033030107 – volume: 75 start-page: 30 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib205 article-title: Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2014-206456 – volume: 3 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib34 article-title: Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA peptide complexes in systemic lupus erythematosus publication-title: Sci. Transl. Med. doi: 10.1126/scitranslmed.3001180 – volume: 71 start-page: 1771 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib157 article-title: Joint european league against rheumatism and european renal association-european dialysis and transplant association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2012-201940 – volume: 162 start-page: 18 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib209 article-title: Multitarget therapy for induction treatment of lupus nephritis: a randomized trial publication-title: Ann. Intern. Med. doi: 10.7326/M14-1030 – volume: 59 start-page: 1796 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib187 article-title: Steroid-sparing effects of methotrexate in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial publication-title: Arthritis Rheum. doi: 10.1002/art.24068 – volume: 65 start-page: 2143 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib230 article-title: Baseline predictors of systemic lupus erythematosus flares: data from the combined placebo groups in the phase III belimumab trials publication-title: Arthritis Rheum. doi: 10.1002/art.37995 – volume: 83 start-page: 51 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib12 article-title: Lessons learned from twins in autoimmune and chronic inflammatory diseases publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2017.04.005 – volume: 64 start-page: 37 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib248 article-title: Photoprotective effects of a broad-spectrum sunscreen in ultraviolet-induced cutaneous lupus erythematosus: a randomized, vehicle-controlled, double-blind study publication-title: J. Am. Acad. Dermatol. doi: 10.1016/j.jaad.2009.12.053 – volume: 24 start-page: 669 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib62 article-title: Smoking is highly associated with discoid lupus erythematosus and lupus erythematosus tumidus: analysis of 405 patients publication-title: Lupus doi: 10.1177/0961203314559630 – volume: 16 start-page: 142 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib239 article-title: Pathophysiology of T follicular helper cells in humans and mice publication-title: Nat. Immunol. doi: 10.1038/ni.3054 – volume: 7 start-page: 914 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib86 article-title: Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or Lupus-like disease publication-title: Clin. J. Am. Soc. Nephrol. doi: 10.2215/CJN.11751111 – volume: 9 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib28 article-title: Aberrant T cell signaling and subsets in systemic lupus erythematosus publication-title: Front. Immunol. doi: 10.3389/fimmu.2018.01088 – volume: 23 start-page: 495 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib66 article-title: Lupus arthritis publication-title: Best Pract. Res. Clin. Rheumatol. doi: 10.1016/j.berh.2009.04.003 – volume: 21 start-page: 241 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib59 article-title: Environment and lupus-related diseases publication-title: Lupus doi: 10.1177/0961203311426568 – volume: 267 start-page: 241 year: 1974 ident: 10.1016/j.jaut.2018.11.001_bib60 article-title: Lupus hair publication-title: Am. J. Med. Sci. doi: 10.1097/00000441-197404000-00005 – volume: 8 start-page: 1702 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib79 article-title: Elevated subclinical double-stranded DNA antibodies and future proliferative lupus nephritis publication-title: Clin. J. Am. Soc. Nephrol. doi: 10.2215/CJN.01910213 – volume: 61 start-page: 1339 year: 2002 ident: 10.1016/j.jaut.2018.11.001_bib196 article-title: FK506 ameliorates proteinuria and glomerular lesions induced by anti-Thy 1.1 monoclonal antibody 1-22-3 publication-title: Kidney Int. doi: 10.1046/j.1523-1755.2002.00259.x – volume: 105 start-page: 5207 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib133 article-title: The vitamin D receptor is required for iNKT cell development publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0711558105 – volume: 36 start-page: 329 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib193 article-title: Mycophenolate mofetil for non-renal manifestations of systemic lupus erythematosus: a systematic review publication-title: Scand. J. Rheumatol. doi: 10.1080/03009740701607042 – volume: 50 start-page: 849 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib17 article-title: Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis publication-title: Arthritis Rheum. doi: 10.1002/art.20049 – volume: 365 start-page: 1886 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib178 article-title: Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa1014460 – volume: 5 start-page: 451 year: 1996 ident: 10.1016/j.jaut.2018.11.001_bib125 article-title: In vivo models of thrombosis for the antiphospholipid syndrome publication-title: Lupus doi: 10.1177/096120339600500524 – volume: 7 start-page: 1 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib136 article-title: Chronic Vitamin D deficiency induces lung fibrosis through activation of the renin-angiotensin system publication-title: Sci. Rep. – volume: 76 start-page: 355 year: 1997 ident: 10.1016/j.jaut.2018.11.001_bib85 article-title: Renal vascular lesions in lupus nephritis publication-title: Medicine (Baltimore) doi: 10.1097/00005792-199709000-00003 – volume: 5 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib242 article-title: S7A:8 Efficacy and safety of ustekinumab, an interleukin 12/23 inhibitor, in patients with active systemic lupus erythematosus: results of a phase 2, randomised placebo-controlled study publication-title: Lupus Sci. Med. – volume: 70 start-page: 571 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib49 article-title: Developing and refining new candidate criteria for systemic lupus erythematosus classification: an international collaboration publication-title: Arthritis Care Res. doi: 10.1002/acr.23317 – volume: 48 start-page: 157 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib69 article-title: Jaccoud's arthropathy in systemic lupus erythematosus: differentiation of deforming and erosive patterns by magnetic resonance imaging publication-title: Arthritis Rheum. doi: 10.1002/art.10753 – volume: 23 start-page: 69 year: 2014 ident: 10.1016/j.jaut.2018.11.001_bib203 article-title: Extended follow-up of the CYCLOFA-LUNE trial comparing two sequential induction and maintenance treatment regimens for proliferative lupus nephritis based either on cyclophosphamide or on cyclosporine A publication-title: Lupus doi: 10.1177/0961203313511555 – volume: 14 start-page: 529 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib266 article-title: High prevalence of vertebral deformity in premenopausal systemic lupus erythematosus patients publication-title: Lupus doi: 10.1191/0961203305lu2154oa – volume: 21 start-page: 84 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib120 article-title: Favorable effects of hydroxychloroquine on serum low density lipid in patients with systemic lupus erythematosus: a systematic review and meta-analysis publication-title: Int. J. Rheum. Dis. doi: 10.1111/1756-185X.13159 – volume: 25 start-page: 2688 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib68 article-title: Ultrasound evaluation of joints in systemic lupus erythematosus: a systematic review publication-title: Eur. Radiol. doi: 10.1007/s00330-015-3670-y – volume: 34 start-page: 40 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib250 article-title: Fibromyalgia prevalence and related factors in a large registry of patients with systemic lupus erythematosus publication-title: Clin. Exp. Rheumatol. – volume: 324 start-page: 150 year: 1991 ident: 10.1016/j.jaut.2018.11.001_bib110 article-title: A randomized study of the effect of withdrawing hydroxychloroquine sulfate in systemic lupus erythematosus publication-title: N. Engl. J. Med. doi: 10.1056/NEJM199101173240303 – volume: 69 issue: suppl year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib135 article-title: Kidney and skin single-cell RNA sequencing in lupus nephritis provides mechanistic insights and novel potential biomarkers publication-title: Arthr. Rheumatol. – volume: 4 start-page: 176 year: 1995 ident: 10.1016/j.jaut.2018.11.001_bib4 article-title: Occasional series: lupus around the World frequency of lupus in people of African origin publication-title: Lupus doi: 10.1177/096120339500400303 – volume: 25 start-page: 191 year: 1996 ident: 10.1016/j.jaut.2018.11.001_bib124 article-title: Thrombosis and systemic lupus erythematosus: the Hopkins Lupus Cohort perspective publication-title: Scand. J. Rheumatol. doi: 10.3109/03009749609069986 – volume: 72 start-page: 634 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib64 article-title: Influence of smoking on the efficacy of antimalarials in cutaneous lupus: a meta-analysis of the literature publication-title: J. Am. Acad. Dermatol. doi: 10.1016/j.jaad.2014.12.025 – volume: 14 start-page: 2 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib188 article-title: Mechanisms of action of mycophenolate mofetil publication-title: Lupus doi: 10.1191/0961203305LU2109OA – volume: 31 start-page: 1557 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib78 article-title: Urine protein-to-creatinine ratio is a reliable measure of proteinuria in lupus nephritis publication-title: J. Rheumatol. – volume: 77 start-page: 937 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib240 article-title: Effect of IL6 and IL23 on double negative T cells and anti ds-DNA in systemic lupus erythematosus patients publication-title: Hum. Immunol. doi: 10.1016/j.humimm.2016.06.007 – volume: 118 start-page: 415 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib130 article-title: American Academy of Ophthalmology, Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy publication-title: Ophthalmology doi: 10.1016/j.ophtha.2010.11.017 – volume: 45 start-page: 217 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib138 article-title: The implication of vitamin D and autoimmunity: a comprehensive review publication-title: Clin. Rev. Allergy Immunol. doi: 10.1007/s12016-013-8361-3 – volume: 63 start-page: 1623 year: 2004 ident: 10.1016/j.jaut.2018.11.001_bib150 article-title: Dehydroepiandrosterone suppresses interleukin 10 synthesis in women with systemic lupus erythematosus publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2003.016576 – volume: 30 start-page: 1955 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib161 article-title: Accrual of organ damage over time in patients with systemic lupus erythematosus publication-title: J. Rheumatol. – volume: 115 start-page: 407 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib99 article-title: Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9 publication-title: J. Clin. Invest. doi: 10.1172/JCI23025 – volume: 82 start-page: 1 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib254 article-title: Cardiovascular disease in systemic lupus erythematosus: a comprehensive update publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2017.05.008 – volume: 199 start-page: 903 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib241 article-title: IL-23 limits the production of IL-2 and promotes autoimmunity in lupus publication-title: J. Immunol. doi: 10.4049/jimmunol.1700418 – year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib192 article-title: Immunosuppressive treatment for proliferative lupus nephritis publication-title: Cochrane Database Syst. Rev. doi: 10.1002/14651858.CD002922.pub4 – volume: 2 start-page: 80 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib260 article-title: Homocysteine in renal injury publication-title: Kidney Dis. (Basel, Switzerland) – volume: 180 start-page: 2329 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib41 article-title: C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition publication-title: J. Immunol. doi: 10.4049/jimmunol.180.4.2329 – volume: 22 start-page: 422 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib265 article-title: Systemic lupus erythematosus, bone health, and osteoporosis publication-title: Curr. Opin. Endocrinol. Diabetes Obes. doi: 10.1097/MED.0000000000000197 – volume: 14 start-page: 106 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib126 article-title: Bone mineral density in postmenopausal Chinese patients with systemic lupus erythematosus publication-title: Lupus doi: 10.1191/0961203305lu2039oa – volume: 17 start-page: 352 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib213 article-title: Pilot 24 month study to compare mycophenolate mofetil and tacrolimus in the treatment of membranous lupus nephritis with nephrotic syndrome publication-title: Nephrology doi: 10.1111/j.1440-1797.2012.01574.x – volume: 16 start-page: 72 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib22 article-title: Mercury as an environmental stimulus in the development of autoimmunity – a systematic review publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2016.09.020 – volume: 52 start-page: 1473 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib111 article-title: Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual publication-title: Arthritis Rheum. doi: 10.1002/art.21039 – volume: 69 start-page: 2083 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib179 article-title: Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2010.131995 – volume: 127 start-page: 513 year: 1992 ident: 10.1016/j.jaut.2018.11.001_bib117 article-title: Treatment of cutaneous lupus erythematosus with acitretin and hydroxychloroquine publication-title: Br. J. Dermatol. doi: 10.1111/j.1365-2133.1992.tb14851.x – volume: 123 start-page: 22 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib134 article-title: Antifibrotic vitamin D analogs – volume: 42 start-page: 1050 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib253 article-title: Fatigue in systemic lupus erythematosus: a randomized controlled trial of exercise publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/keg289 – volume: 22 start-page: 1286 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib263 article-title: Infection risk in systemic lupus erythematosus patients: susceptibility factors and preventive strategies publication-title: Lupus doi: 10.1177/0961203313493032 – volume: 35 start-page: 1567 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib154 article-title: Effects of prasterone on bone mineral density in women with active systemic lupus erythematosus receiving chronic glucocorticoid therapy publication-title: J. Rheumatol. – volume: 36 start-page: 82 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib249 article-title: Fibromyalgia, systemic lupus erythematosus (SLE), and evaluation of SLE activity publication-title: J. Rheumatol. doi: 10.3899/jrheum.080212 – volume: 45 start-page: 86 year: 2001 ident: 10.1016/j.jaut.2018.11.001_bib58 article-title: Phototesting in lupus erythematosus: a 15-year experience publication-title: J. Am. Acad. Dermatol. doi: 10.1067/mjd.2001.114589 – volume: 35 start-page: 1776 year: 2008 ident: 10.1016/j.jaut.2018.11.001_bib96 article-title: Cognitive function in a systemic lupus erythematosus inception cohort publication-title: J. Rheumatol. – volume: 174 start-page: 357 year: 1986 ident: 10.1016/j.jaut.2018.11.001_bib94 article-title: Prevalence of cognitive impairment in systemic lupus erythematosus publication-title: J. Nerv. Ment. Dis. doi: 10.1097/00005053-198606000-00008 – volume: 43 start-page: 1801 year: 2000 ident: 10.1016/j.jaut.2018.11.001_bib164 article-title: Damage in systemic lupus erythematosus and its association with corticosteroids publication-title: Arthritis Rheum. doi: 10.1002/1529-0131(200008)43:8<1801::AID-ANR16>3.0.CO;2-O – volume: 176 start-page: 708 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib162 article-title: Incidence of and risk factors for adverse cardiovascular events among patients with systemic lupus erythematosus publication-title: Am. J. Epidemiol. doi: 10.1093/aje/kws130 – volume: 72 start-page: 1280 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib158 article-title: Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2012-202844 – volume: 42 start-page: 2026 year: 1999 ident: 10.1016/j.jaut.2018.11.001_bib89 article-title: Neuroimaging in neuropsychiatric systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/1529-0131(199910)42:10<2026::AID-ANR2>3.0.CO;2-J – volume: 4 start-page: 377 year: 2005 ident: 10.1016/j.jaut.2018.11.001_bib152 article-title: Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders publication-title: Curr. Drug Targets Inflamm. Allergy doi: 10.2174/1568010054022079 – volume: 189 start-page: 2689 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib32 article-title: Neutrophil extracellular traps: double-edged swords of innate immunity publication-title: J. Immunol. doi: 10.4049/jimmunol.1201719 – volume: 48 start-page: 1616 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib84 article-title: Lupus podocytopathy publication-title: Rheumatology doi: 10.1093/rheumatology/kep256 – volume: 71 start-page: 1502 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib114 article-title: Seizure disorders in systemic lupus erythematosus results from an international, prospective, inception cohort study publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2011-201089 – volume: 58 start-page: 1025 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib258 article-title: Homocysteine and reclassification of cardiovascular disease risk publication-title: J. Am. Coll. Cardiol. doi: 10.1016/j.jacc.2011.05.028 – volume: 54 start-page: 2550 year: 2006 ident: 10.1016/j.jaut.2018.11.001_bib74 article-title: Mortality in systemic lupus erythematosus publication-title: Arthritis Rheum. doi: 10.1002/art.21955 – volume: 14 start-page: 639 year: 1971 ident: 10.1016/j.jaut.2018.11.001_bib175 article-title: Azathioprine in the treatment of systemic lupus erythematosus. A controlled study publication-title: Arthritis Rheum. doi: 10.1002/art.1780140511 – volume: 27 start-page: 1467 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib200 article-title: Mycophenolate mofetil or tacrolimus compared with intravenous cyclophosphamide in the induction treatment for active lupus nephritis publication-title: Nephrol. Dial. Transplant. doi: 10.1093/ndt/gfr484 – volume: 48 start-page: 2100 year: 2003 ident: 10.1016/j.jaut.2018.11.001_bib147 article-title: Sex hormones and systemic lupus erythematosus: review and meta-analysis publication-title: Arthritis Rheum. doi: 10.1002/art.11105 – volume: 19 start-page: 371 year: 1997 ident: 10.1016/j.jaut.2018.11.001_bib14 article-title: Echinacea-induced cytokine production by human macrophages publication-title: Int. J. Immunopharmacol. doi: 10.1016/S0192-0561(97)00061-1 – volume: 68 issue: suppl year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib159 article-title: Speed of remission with the use of voclosporin, MMF and low dose steroids: results of a global lupus nephritis study [abstract] publication-title: Arthr. Rheumatol. – volume: 25 start-page: 3939 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib207 article-title: Long-term outcomes - mycophenolate mofetil treatment for lupus nephritis with addition of tacrolimus for resistant cases publication-title: Nephrol. Dial. Transplant. doi: 10.1093/ndt/gfq322 – volume: 19 start-page: 265 year: 1992 ident: 10.1016/j.jaut.2018.11.001_bib16 article-title: Antibiotic allergy in systemic lupus erythematosus: a case-control study publication-title: J. Rheumatol. – volume: 186 start-page: 4794 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib100 article-title: Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines publication-title: J. Immunol. doi: 10.4049/jimmunol.1000702 – year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib27 – year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib166 article-title: Cytotoxic-immunosuppressive drug treatment – volume: 31 start-page: 429 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib195 article-title: Calcineurin inhibitors in systemic lupus erythematosus publication-title: Best Pract. Res. Clin. Rheumatol. doi: 10.1016/j.berh.2017.09.010 – volume: 20 start-page: 1103 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib191 article-title: Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis publication-title: J. Am. Soc. Nephrol. doi: 10.1681/ASN.2008101028 – volume: 65 start-page: 1865 year: 2013 ident: 10.1016/j.jaut.2018.11.001_bib143 article-title: Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein-to-creatinine ratio publication-title: Arthritis Rheum. doi: 10.1002/art.37953 – volume: 68 start-page: 91 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib144 article-title: Vitamin D supplementation in adolescents and young adults with juvenile systemic lupus erythematosus for improvement in disease activity and fatigue scores: a randomized, double-blind, placebo-controlled trial publication-title: Arthritis Care Res. (Hoboken). doi: 10.1002/acr.22621 – volume: 56 start-page: 4142 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib245 article-title: Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial publication-title: Arthritis Rheum. doi: 10.1002/art.23047 – volume: 44 start-page: 1122 year: 2001 ident: 10.1016/j.jaut.2018.11.001_bib20 article-title: Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure publication-title: Arthritis Rheum. doi: 10.1002/1529-0131(200105)44:5<1122::AID-ANR193>3.0.CO;2-D – volume: 37 start-page: 57 year: 1994 ident: 10.1016/j.jaut.2018.11.001_bib18 article-title: Increased antiretroviral antibody reactivity in sera from a defined population of patients with systemic lupus erythematosus: correlation with autoantibodies and clinical manifestations publication-title: Arthritis Rheum. doi: 10.1002/art.1780370109 – volume: 44 start-page: 175 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib218 article-title: Efficacy and safety of rituximab in the treatment of non-renal systemic lupus erythematosus: a systematic review publication-title: Semin. Arthritis Rheum. doi: 10.1016/j.semarthrit.2014.04.002 – volume: 8 start-page: 456 year: 2009 ident: 10.1016/j.jaut.2018.11.001_bib39 article-title: Clinic and pathophysiology of photosensitivity in lupus erythematosus publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2008.12.012 – volume: 76 start-page: 459 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib171 article-title: Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives publication-title: Drugs doi: 10.1007/s40265-015-0534-3 – year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib53 – volume: 34 start-page: 332 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib77 article-title: Renal biopsy in lupus patients with low levels of proteinuria publication-title: J. Rheumatol. – volume: 70 issue: suppl year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib50 article-title: Validation of proposed EULAR/acr SLE classification criteria versus SLICC SLE classification criteria publication-title: Arthr. Rheumatol. – volume: 66 start-page: 470 year: 2007 ident: 10.1016/j.jaut.2018.11.001_bib170 article-title: Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system publication-title: Ann. Rheum. Dis. doi: 10.1136/ard.2006.057885 – volume: 18 start-page: 1 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib45 article-title: Monogenic lupus publication-title: Curr. Rheumatol. Rep. doi: 10.1007/s11926-016-0621-9 – volume: 39 start-page: 257 year: 2010 ident: 10.1016/j.jaut.2018.11.001_bib5 article-title: Understanding the epidemiology and progression of systemic lupus erythematosus publication-title: Semin. Arthritis Rheum. doi: 10.1016/j.semarthrit.2008.10.007 – volume: 21 start-page: 1178 year: 2012 ident: 10.1016/j.jaut.2018.11.001_bib122 article-title: Hydroxychloroquine reduces low-density lipoprotein cholesterol levels in systemic lupus erythematosus: a longitudinal evaluation of the lipid-lowering effect publication-title: Lupus doi: 10.1177/0961203312450084 – volume: 314 start-page: 614 year: 1986 ident: 10.1016/j.jaut.2018.11.001_bib168 article-title: Therapy of lupus nephritis publication-title: N. Engl. J. Med. doi: 10.1056/NEJM198603063141004 – volume: 5 year: 2018 ident: 10.1016/j.jaut.2018.11.001_bib70 article-title: Measuring lupus arthritis activity using contrasted high-field MRI. Associations with clinical measures of disease activity and novel patterns of disease publication-title: Lupus Sci. Med. doi: 10.1136/lupus-2018-000264 – volume: 76 year: 2017 ident: 10.1016/j.jaut.2018.11.001_bib261 article-title: Homocysteine, antiphospholipid antibodies and risk of vascular events in patients with systemic lupus erythematosus [Abstract] publication-title: Ann. Rheum. Dis. – volume: 2 start-page: 1 year: 1965 ident: 10.1016/j.jaut.2018.11.001_bib185 article-title: Diagnosis and treatment of systemic lupus erythematosus publication-title: Semin. Hematol. – volume: 31 start-page: 1053 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib172 article-title: Con: cyclophosphamide for the treatment of lupus nephritis publication-title: Nephrol. Dial. Transplant. doi: 10.1093/ndt/gfw068 – volume: 58 start-page: 2336 year: 2015 ident: 10.1016/j.jaut.2018.11.001_bib123 article-title: Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial publication-title: Diabetologia doi: 10.1007/s00125-015-3689-2 – volume: 3 year: 2016 ident: 10.1016/j.jaut.2018.11.001_bib264 article-title: Risk factors for osteoporosis and fragility fractures in patients with systemic lupus erythematosus publication-title: Lupus Sci. Med. doi: 10.1136/lupus-2015-000098 – volume: 20 start-page: 1267 year: 2011 ident: 10.1016/j.jaut.2018.11.001_bib81 article-title: Anti-C1q antibodies have higher correlation with flares of lupus nephritis than other serum markers publication-title: Lupus doi: 10.1177/0961203311411597 |
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| Snippet | Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Genetic predisposition, environmental... |
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| SubjectTerms | Animals Diagnosis Humans Immunologic Factors - therapeutic use Immunosuppressive Agents - therapeutic use Life Style Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - therapy Management Molecular Targeted Therapy Systemic lupus erythematosus Ultraviolet Rays Vitamin D - therapeutic use |
| Title | Systemic lupus erythematosus: Diagnosis and clinical management |
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