Significant morphological change in osteoarthritic hips identified over 6–12 months using statistical shape modelling

• Published in: Osteoarthritis and cartilage Vol. 26; no. 6; pp. 783 - 789
• Main Authors: Barr, R.J., Gregory, J.S., Yoshida, K., Alesci, S., Aspden, R.M., Reid, D.M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2018
• Subjects: Absorptiometry, Photon; Aged; Disease Progression; DXA; Female; Hip; Humans; Male; Middle Aged; Models, Statistical; Morphology; Osteoarthritis; Osteoarthritis, Hip - diagnostic imaging; Osteoarthritis, Hip - pathology; Prospective Studies; Radiographic; Rheumatology; Statistical shape modelling; Time Factors; Statistical shape modelling; DXA; Radiographic; Osteoarthritis; Morphology; Hip

Predicting who will develop osteoarthritis, assessing how rapidly their disease will progress and monitoring early responses to treatment are key to the development of therapeutic agents able to treat this crippling disease and to their future clinical use. Statistical Shape Modelling (SSM) enables...