Sensitive Skin: Assessment of the Skin Barrier Using Confocal Raman Microspectroscopy

• Published in: Skin pharmacology and physiology Vol. 30; no. 1; pp. 1 - 12
• Main Authors: Richters, Renée J.H., Falcone, Denise, Uzunbajakava, Natallia E., Varghese, Babu, Caspers, Peter J., Puppels, Gerwin J., van Erp, Piet E.J., van de Kerkhof, Peter C.M.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 2017
• Subjects: Adolescent; Adult; Ceramides - analysis; Conjunctivitis, Allergic - metabolism; Dermatitis, Atopic - metabolism; Fatty Acids - analysis; Female; Glycerol - pharmacokinetics; Humans; Male; Original Paper; Rhinitis, Allergic - metabolism; Skin - chemistry; Skin - metabolism; Skin Absorption; Spectrum Analysis, Raman; Young Adult; Stratum corneum; Atopic dermatitis; Confocal Raman microspectroscopy; Capacitance; Transepidermal water loss; Sensitive skin; Skin barrier function; Skin barrier molecular composition

Background/Aims: Sensitive skin (SS), a frequently reported condition in the Western world, has been suggested to be underlined by an impaired skin barrier. The aim of this study was to investigate the skin barrier molecular composition in SS subjects using confocal Raman microspectroscopy (CRS), an...