Role of Interleukin-10 in Acute Brain Injuries

• Published in: Frontiers in neurology Vol. 8; p. 244
• Main Authors: Garcia, Joshua M., Stillings, Stephanie A., Leclerc, Jenna L., Phillips, Harrison, Edwards, Nancy J., Robicsek, Steven A., Hoh, Brian L., Blackburn, Spiros, Doré, Sylvain
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 12.06.2017
• Subjects: concussion; endothelium; intracerebral hemorrhage; ischemia; Neuroscience; stroke; subarachnoid hemorrhage; intracerebral hemorrhage; endothelium; vasculature; subarachnoid hemorrhage; traumatic brain injury; concussion; stroke; ischemia

Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged causes secondary brain damage. Here, we comprehensively review the current knowledge regarding the role of IL-10 i...