Elevated Serum Growth Differentiation Factor 15 Levels in Hyperthyroid Patients

• Published in: Frontiers in endocrinology (Lausanne) Vol. 9; p. 793
• Main Authors: Zhao, Jiejie, Li, Min, Chen, Ying, Zhang, Shengjie, Ying, Hao, Song, Zhiyi, Lu, Yan, Li, Xiaoying, Xiong, Xuelian, Jiang, Jingjing
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 09.01.2019
• Subjects: brown adipose tissue; cytokine; Endocrinology; growth differentiation factor 15; hyperthyroidism; thyroid hormone; cytokine; hyperthyroidism; brown adipose tissue; thyroid hormone; growth differentiation factor 15

Recent studies have shown that growth differentiation factor 15 (GDF15), a member of the transforming growth factor-β (TGF-β)/bone morphogenetic protein (BMP) superfamily, plays an important role in appetite, type 2 diabetes, and cardiovascular diseases. Since thyroid hormone has pleiotropic effects...