Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study

• Published in: Frontiers in oncology Vol. 11; p. 637116
• Main Authors: Cattaneo, Daniele, Croci, Giorgio Alberto, Bucelli, Cristina, Tabano, Silvia, Cannone, Marta Giulia, Gaudioso, Gabriella, Barbanti, Maria Chiara, Barbullushi, Kordelia, Bianchi, Paola, Fermo, Elisa, Fabris, Sonia, Baldini, Luca, Gianelli, Umberto, Iurlo, Alessandra
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 12.03.2021
• Subjects: bone marrow morphology; essential thrombocytemia; next-generation sequencing; Oncology; prognosis; triple-negative; essential thrombocytemia; bone marrow morphology; next-generation sequencing; prognosis; triple-negative

Lack of demonstrable mutations affecting JAK2, CALR , or MPL driver genes within the spectrum of BCR-ABL1 -negative myeloproliferative neoplasms (MPNs) is currently referred to as a triple-negative genotype, which is found in about 10% of patients with essential thrombocythemia (ET) and 5–10% of tho...