Comparative Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Advanced Cancer: A Systematic Review and Meta-Analysis

• Published in: Frontiers in pharmacology Vol. 11; p. 40
• Main Authors: Yang, Yi, Jin, Gang, Pang, Yao, Huang, Yijie, Wang, Wenhao, Zhang, Hongyi, Tuo, Guangxin, Wu, Peng, Wang, Zequan, Zhu, Zijiang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 14.02.2020
• Subjects: advanced cancer; combination immunotherapy; efficacy; ipilimumab; nivolumab; Pharmacology; safety; combination immunotherapy; advanced cancer; nivolumab; safety; efficacy; ipilimumab

Combination therapy with immune checkpoint inhibitors (ICIs) has been applied in the clinic to achieve synergistic effects and to improve clinical efficacy. Compared with monotherapy, combination therapy has promising efficacy against various advanced cancers. To further verify the effectiveness of...