Studies on B Cells in the Fruit-Eating Black Flying Fox ( Pteropus alecto)

• Published in: Frontiers in immunology Vol. 10; p. 489
• Main Authors: Periasamy, Pravin, Hutchinson, Paul E, Chen, Jinmiao, Bonne, Isabelle, Shahul Hameed, Shahana Shereene, Selvam, Pavithra, Hey, Ying Ying, Fink, Katja, Irving, Aaron T, Dutertre, Charles-Antoine, Baker, Michelle, Crameri, Gary, Wang, Lin-Fa, Alonso, Sylvie
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 14.03.2019
• Subjects: adaptive immunity; Animals; Antigens, Differentiation - immunology; B-Lymphocytes - immunology; bat; Bone Marrow Cells - immunology; Chiroptera - immunology; cross-reactive antibodies; Eonycteris spelaea; Immunology; Killer Cells, Natural - immunology; Pteropus alecto; Receptors, Antigen, B-Cell - immunology; Pteropus alecto; cross-reactive antibodies; Eonycteris spelaea; bat; adaptive immunity

The ability of bats to act as reservoir for viruses that are highly pathogenic to humans suggests unique properties and functional characteristics of their immune system. However, the lack of bat specific reagents, in particular antibodies, has limited our knowledge of bat's immunity. Here, we...