A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction

• Published in: European heart journal Vol. 35; no. 15; pp. 999 - 1006
• Main Authors: Jaguszewski, M., Osipova, J., Ghadri, J.-R., Napp, L. C., Widera, C., Franke, J., Fijalkowski, M., Nowak, R., Fijalkowska, M., Volkmann, I., Katus, H. A., Wollert, K. C., Bauersachs, J., Erne, P., Luscher, T. F., Thum, T., Templin, C.
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.04.2014
• Series: Editor's choice
• Subjects: Aged; Basic Science; Biomarkers - metabolism; Early Diagnosis; Endothelin-1 - metabolism; Female; Humans; Male; MicroRNAs - metabolism; Myocardial Infarction - diagnosis; Reproducibility of Results; Risk Factors; ROC Curve; Takotsubo Cardiomyopathy - diagnosis; Biomarker; Takotsubo cardiomyopathy; MicroRNA; Endothelin-1

Takotsubo cardiomyopathy (TTC) remains a potentially life-threatening disease, which is clinically indistinguishable from acute myocardial infarction (MI). Today, no established biomarkers are available for the early diagnosis of TTC and differentiation from MI. MicroRNAs (miRNAs/miRs) emerge as pro...