Transplanting Marginal Organs in the Era of Modern Machine Perfusion and Advanced Organ Monitoring

• Published in: Frontiers in immunology Vol. 11; p. 631
• Main Authors: Resch, Thomas, Cardini, Benno, Oberhuber, Rupert, Weissenbacher, Annemarie, Dumfarth, Julia, Krapf, Christoph, Boesmueller, Claudia, Oefner, Dietmar, Grimm, Michael, Schneeberger, Sefan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 12.05.2020
• Subjects: Anti-Inflammatory Agents; graft; Humans; immunogenecity; Immunology; Immunomodulation; machine perfusion; marginal; Organ Preservation - methods; Organ Transplantation - methods; Perfusion - methods; Reperfusion Injury - prevention & control; Stem Cells - immunology; Tissue Donors; Transduction, Genetic - methods; transplantation; Transplants - immunology; immunomodulation; machine perfusion; graft; transplantation; expanded criteria donor; marginal; immunogenecity; reconditioning

Organ transplantation is undergoing profound changes. Contraindications for donation have been revised in order to better meet the organ demand. The use of lower-quality organs and organs with greater preoperative damage, including those from donation after cardiac death (DCD), has become an establi...