Extracellular Matrix From Decellularized Wharton's Jelly Improves the Behavior of Cells From Degenerated Intervertebral Disc

• Published in: Frontiers in bioengineering and biotechnology Vol. 8; p. 262
• Main Authors: Penolazzi, Letizia, Pozzobon, Michela, Bergamin, Leticia Scussel, D'Agostino, Stefania, Francescato, Riccardo, Bonaccorsi, Gloria, De Bonis, Pasquale, Cavallo, Michele, Lambertini, Elisabetta, Piva, Roberta
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.03.2020
• Subjects: Bioengineering and Biotechnology; decellularized matrix; intervertebral disc cells; scaffold; TRPS1; Wharton’s jelly; intervertebral disc cells; Wharton’s jelly; scaffold; TRPS1; decellularized matrix

Regenerative therapies for intervertebral disc (IVD) injuries are currently a major challenge that is addressed in different ways by scientists working in this field. Extracellular matrix (ECM) deriving from decellularized non-autologous tissues has been established as a biomaterial with remarkable...