Molecular imaging in drug development

• Published in: Nature reviews. Drug discovery Vol. 7; no. 7; pp. 591 - 607
• Main Authors: Willmann, Jürgen K., van Bruggen, Nicholas, Dinkelborg, Ludger M., Gambhir, Sanjiv S.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2008; Nature Publishing Group
• Subjects: Animals; Biomarkers; Biomedical and Life Sciences; Biomedicine; Biotechnology; Cancer Research; Diagnostic Imaging; Drug Design; Drugs; Humans; Medicinal Chemistry; Methods; Molecular Medicine; Pharmacokinetics; Pharmacology/Toxicology; Product/Service Evaluations; review-article; United States

Key Points Drug development is a costly, time-intensive and high-risk endeavour, with only two to three approvals for novel therapeutics in new drug classes per year eventually making it to market. New strategies are required to identify promising new drug candidates early on and, likewise, to termi...