Safety and possible outcome assessment of autologous Schwann cell and bone marrow mesenchymal stromal cell co-transplantation for treatment of patients with chronic spinal cord injury

• Published in: Cytotherapy (Oxford, England) Vol. 15; no. 7; pp. 782 - 791
• Main Authors: Yazdani, Saeed Oraee, Hafizi, Maryam, Zali, Ali-Reza, Atashi, Amir, Ashrafi, Farzad, Seddighi, Amir-Saeed, Soleimani, Masoud
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.07.2013
• Subjects: Adolescent; Adult; Advanced Basic Science; bone marrow; cell transplantation; combination therapy; Female; Humans; Male; Mesenchymal Stem Cell Transplantation; mesenchymal stromal cell; Mesenchymal Stromal Cells - cytology; Middle Aged; Other; Outcome Assessment (Health Care); Schwann cell; Schwann Cells - cytology; Spinal Cord Injuries - pathology; Spinal Cord Injuries - therapy; Spinal Cord Regeneration; spinal cord repair; Transplantation, Autologous; Treatment Outcome; cell transplantation; combination therapy; spinal cord repair; mesenchymal stromal cell; Schwann cell; bone marrow

Cell replacement therapy has become a promising issue that has raised much hope in the regeneration of central nervous system injury. Evidence indicates that successful functional recovery in patients with spinal cord injury will not simply emphasize a single therapeutic strategy. Therefore, many re...