Increased symmetrical dimethylarginine in ischemic acute kidney injury as a causative factor of renal L-arginine deficiency - Betz, Boris; Möller-Ehrlich, Kerstin; Kress, Tobias; Kniepert, Joachim; Schwedhelm, Edzard; Böger, Rainer H.; Wanner, Christoph; Sauvant, Christoph; Schneider, Reinhard (Translational research : the journal of laboratory and clinical medicine, 2013)
Keywords: Acute Kidney Injury - metabolism; Acute Kidney Injury - physiopathology; Amidohydrolases - metabolism; Animals; Arginine - analogs & derivatives; Arginine - blood; Arginine - deficiency; Arginine - metabolism; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Internal Medicine; Intracellular Signaling Peptides and Proteins - metabolism; Kidney - metabolism; Kidney Function Tests; Protein-Arginine N-Methyltransferases - metabolism; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury - metabolism; Reperfusion Injury - physiopathology; Tandem Mass Spectrometry; eNOS; GFR; NOS; SDMA; PAH; CAT; DDAH; ADMA; iNOS; RPF; PRMT; PCR; para-aminohippurate; glomerular filtration rate; asymmetrical dimethylarginine; cationic amino acid transporter; symmetrical dimethylarginine; inducible nitric oxide synthase; protein arginine methyltransferase; renal plasma flow; dimethylarginine dimethylaminohydrolase; endothelial nitric oxide synthase; nitric oxide synthase; polymerase chain reaction