Serological response and diagnostic value of recombinant candida cell wall protein enolase, phosphoglycerate kinase, and β-glucosidase

• Published in: Frontiers in microbiology Vol. 6; p. 920
• Main Authors: He, Zheng-xin, Chen, Jing, Li, Wei, Cheng, Yan, Zhang, Hai-pu, Zhang, Li-na, Hou, Tian-wen
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 10.09.2015
• Subjects: enolase; Immunology; Invasive candidiasis; Phosphoglycerate Kinase; Serodiagnosis; serological response; β-glucosidase; invasive candidiasis; serodiagnosis; enolase; serological response; β-glucosidase; phosphoglycerate kinase

There are no specific signs and symtoms for invasive candidiasis (IC), which makes its diagnosis a challenge. Efforts have been made for decades to establish serological assays for rapid diagnosis of IC, but none of them have found widespread clinical use. Using a systemic candiasis murine model, se...