Identification of Key Pathways and Genes Related to Immunotherapy Resistance of LUAD Based on WGCNA Analysis

• Published in: Frontiers in oncology Vol. 11; p. 814014
• Main Authors: Yu, Weina, Liu, Fengsen, Lei, Qingyang, Wu, Peng, Yang, Li, Zhang, Yi
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 06.01.2022
• Subjects: cancer stem cell; immunotherapy resistance; LUAD; Oncology; TIDE; WGCNA; TIDE; immunotherapy resistance; cancer stem cell; WGCNA; LUAD

Immunotherapy resistance is a major barrier in the application of immune checkpoint inhibitors (ICI) in lung adenocarcinoma (LUAD) patients. Although recent studies have found several mechanisms and potential genes responsible for immunotherapy resistance, ways to solve this problem are still lackin...