Coexistence of EGFR, KRAS, BRAF, and PIK3CA Mutations and ALK Rearrangement in a Comprehensive Cohort of 326 Consecutive Spanish Nonsquamous NSCLC Patients - Martín Martorell, Paloma; Huerta, Marisol; Compañ Quilis, Amparo; Abellán, Rosario; Seda, Enrique; Blesa, Sebastián; Chaves, Felipe J.; Dualde Beltrán, Diego; Roselló Keränen, Susana; Franco, José; Insa, Amelia (Clinical lung cancer, 2017)
Keywords: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung - genetics; Carcinoma, Non-Small-Cell Lung - pathology; Carcinoma, Non-Small-Cell Lung - therapy; Class I Phosphatidylinositol 3-Kinases - genetics; Cohort Studies; Driver mutation; Female; Gene Rearrangement; Hematology, Oncology and Palliative Medicine; Humans; Lung Neoplasms - genetics; Lung Neoplasms - pathology; Lung Neoplasms - therapy; Male; Middle Aged; Molecular Targeted Therapy; Mutation; Mutational co-existence; Neoplasm Staging; Next-generation sequencing (NGS); Non–small-cell lung cancer; Prospective Studies; Proto-Oncogene Proteins B-raf - genetics; Proto-Oncogene Proteins p21(ras) - genetics; Pulmonary/Respiratory; Receptor Protein-Tyrosine Kinases - genetics; Receptor, Epidermal Growth Factor - genetics; Spain; Treatment response; Driver mutation; Non–small-cell lung cancer; Treatment response; Mutational co-existence; Next-generation sequencing (NGS)