Chemical Biology Strategies to Study Autophagy

• Published in: Frontiers in cell and developmental biology Vol. 6; p. 160
• Main Authors: Mishra, Piyush, Ammanathan, Veena, Manjithaya, Ravi
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.11.2018
• Subjects: autophagy; Cell and Developmental Biology; chemical biology; fluorescence microscopy; high throughput; luciferase; small molecule screening; luciferase; small molecule screening; autophagy; chemical biology; fluorescence microscopy; high throughput

Growing amount of evidence in the last two decades highlight that macroautophagy (generally referred to as autophagy) is not only indispensable for survival in yeast but also equally important to maintain cellular quality control in higher eukaryotes as well. Importantly, dysfunctional autophagy has...