Jiang Tang Xiao Ke Granule Protects Hepatic Tissue of Diabetic Mice Through Modulation of Insulin and Ras Signaling - A Bioinformatics Analysis of MicroRNAs and mRNAs Network

• Published in: Frontiers in pharmacology Vol. 11; p. 173
• Main Authors: Bai, Ying, Bao, Xueli, Jiang, Guangjian, Ge, Dongyu, He, Weipeng, Zhao, Dandan, Zhang, Yi, Dong, Ruijuan, Hua, Jing, Yang, Nan, Mo, Fangfang, Gao, Sihua
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 06.03.2020
• Subjects: anti-diabetic effect; bioinformatic analysis; diabetes mellitus; Jiang Tang Xiao Ke Granule; microRNAs; Pharmacology; microRNAs; diabetes mellitus; Jiang Tang Xiao Ke Granule; anti-diabetic effect; bioinformatic analysis

To investigate the impact of JTXK granule on the miRNA expression profiles in hepatic tissue of diabetic mice, and to explore the molecular targets and associated signaling pathways of JTXK granule in its anti-diabetic effect. Eight mice were randomly selected as normal group fed with chow diet. The...