Increased Chemerin and Decreased Omentin-1 in Both Adipose Tissue and Plasma in Nascent Metabolic Syndrome

• Published in: The journal of clinical endocrinology and metabolism Vol. 98; no. 3; pp. E514 - E517
• Main Authors: Jialal, Ishwarlal, Devaraj, Sridevi, Kaur, Harmeet, Adams-Huet, Beverley, Bremer, Andrew A.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.03.2013; Copyright by The Endocrine Society
• Subjects: Adipose tissue; Adult; Biopsy; Blood Glucose - metabolism; Blood pressure; Body fat; Body mass index; C-reactive protein; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - metabolism; Chemokines - blood; Chemokines - metabolism; Cholesterol; Cytokines - blood; Cytokines - metabolism; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - metabolism; Female; GPI-Linked Proteins - blood; GPI-Linked Proteins - metabolism; Heme Oxygenase-1 - physiology; High density lipoprotein; Homeostasis; Humans; Insulin resistance; Intercellular Signaling Peptides and Proteins; Lectins - blood; Lectins - metabolism; Lipids - blood; Male; Metabolic syndrome; Metabolic Syndrome - epidemiology; Metabolic Syndrome - metabolism; Middle Aged; Nicotinamide Phosphoribosyltransferase - blood; Nicotinamide Phosphoribosyltransferase - metabolism; Plasma levels; Resistin - blood; Resistin - metabolism; Risk Factors; Subcutaneous Fat - metabolism; Triglycerides

Context:Adipose tissue dysregulation causing aberrant adipokine secretion contributes toward the proinflammatory state of metabolic syndrome (MetS). However, there are scant data on the role of novel adipokines in MetS.Objective:The aim of this study was to determine the levels of circulating and ad...