The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects - Cavallone, Laura F.; Montana, Michael C.; Frey, Karen; Kallogjeri, Dorina; Wages, James M.; Rodebaugh, Thomas L.; Doshi, Tina; Kharasch, Evan D.; Gereau, Robert W. (Pain (Amsterdam), 2020)
Keywords: Adult; Analgesics - pharmacokinetics; Analgesics - pharmacology; Analgesics - therapeutic use; Double-Blind Method; Excitatory Amino Acid Antagonists - pharmacokinetics; Excitatory Amino Acid Antagonists - pharmacology; Excitatory Amino Acid Antagonists - therapeutic use; Female; Healthy Volunteers; Humans; Hyperalgesia - drug therapy; Imidazoles - pharmacokinetics; Imidazoles - pharmacology; Imidazoles - therapeutic use; Male; Middle Aged; Pain - drug therapy; Pain Measurement; Receptor, Metabotropic Glutamate 5 - antagonists & inhibitors; Treatment Outcome; Young Adult