In vitro response of monocyte-derived macrophages to a decellularized pericardial biomaterial

• Published in: Journal of biomedical materials research. Part A Vol. 93A; no. 1; pp. 280 - 288
• Main Authors: Ariganello, Marianne B., Labow, Rosalind S., Lee, J. Michael
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.04.2010; Wiley-Blackwell
• Subjects: acid phosphatase; Acid Phosphatase - metabolism; Animals; Biocompatible Materials - pharmacology; Biological and medical sciences; biomaterials; Biotechnology; Cells, Cultured; collagen; decellularized bovine pericardium; DNA - metabolism; Esterases - metabolism; Fundamental and applied biological sciences. Psychology; Health. Pharmaceutical industry; Humans; Immunoblotting; Industrial applications and implications. Economical aspects; Intracellular Space - drug effects; Intracellular Space - metabolism; macrophage; Macrophages - cytology; Macrophages - drug effects; Macrophages - enzymology; Macrophages - ultrastructure; Medical sciences; Microscopy, Confocal; Miscellaneous; Pericardium - cytology; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology. Biomaterials. Equipments; Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels; Cell culture; Prosthesis; Phosphoric monoester hydrolases; Esterases; Scaffold; Heart valve; Styrene polymer; Biomaterial; biomaterials; Ungulata; Biomedical engineering; Dimethylsiloxane polymer; Bovine; Monocyte; Enzyme; Tissue engineering; Glycoprotein; In vitro; Pericardium; decellularized bovine pericardium; Vertebrata; Mammalia; Collagen; Animal protein; Hydrolases; Circulatory system; Artiodactyla; Acid phosphatase; Comparative study; Macrophage

Decellularized tissue‐derived heart valves are an example of biomaterials derived from natural scaffolds. These types of implants are increasing in popularity although their in vivo performance is still only poorly understood and has, at times, been catastrophic. It is apparent that better understan...