Inhaled formaldehyde exposure: effect on bronchial response to mite allergen in sensitized asthma patients

• Published in: Allergy Vol. 61; no. 11; pp. 1344 - 1350
• Main Authors: Casset, A., Marchand, C., Purohit, A., Le Calve, S., Uring‐Lambert, B., Donnay, C., Meyer, P., De Blay, F.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.11.2006; Blackwell; Wiley
• Subjects: Adult; Air Pollutants - toxicity; Allergic diseases; Animals; Antigens, Dermatophagoides - immunology; Arthropod Proteins; asthma; Asthma - chemically induced; Asthma - etiology; Asthma - immunology; Biological and medical sciences; Bronchi - drug effects; Bronchi - immunology; bronchial responsiveness; Continental interfaces, environment; Cysteine Endopeptidases; Der p 1; Dermatophagoides pteronyssinus; Dermatophagoides pteronyssinus - immunology; Earth Sciences; Eosinophil Cationic Protein - blood; Female; formaldehyde; Formaldehyde - toxicity; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Geochemistry; house dust mite allergen; Humans; Immunopathology; Inhalation Exposure; Male; Medical sciences; Methacholine Chloride - pharmacology; Sciences of the Universe; Sputum - cytology; Allergy; Der p 1; Mite; bronchial responsiveness; Respiratory system; Formaldehyde; Respiratory tract; Immunology; Acari; Bronchus disease; Sensitization; Obstructive pulmonary disease; Human; Immunopathology; Lung disease; Respiratory disease; House dust; Acaridida; Exposure; Dermatophagoides pteronyssinus; Asthma; Inhalation; Acariformes; Arachnida; Arthropoda; Pyroglyphidae; Invertebrata; house dust mite allergen

Background:  Formaldehyde, an indoor air pollutant, is known to be an irritant and an etiologic factor in occupational asthma. An epidemiologic study suggests that it may also increase the risk of childhood asthma for concentrations above 60 μg/m3. Aim:  To evaluate the influence of pre‐exposure to...