The rise, fall and renaissance of microsatellites in eukaryotic genomes

• Published in: BioEssays Vol. 28; no. 10; pp. 1040 - 1050
• Main Authors: Buschiazzo, Emmanuel, Gemmell, Neil J.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.10.2006
• Subjects: Animals; Base Sequence; Eukaryotic Cells; Evolution, Molecular; Genome; Humans; Microsatellite Repeats; Models, Genetic; Mutation; Selection, Genetic

Microsatellites are among the most versatile of genetic markers, being used in an impressive number of biological applications. However, the evolutionary dynamics of these markers remain a source of contention. Almost 20 years after the discovery of these ubiquitous simple sequences, new genomic dat...