Identification of long non-coding RNAs in response to nanopolystyrene in Caenorhabditis elegans after long-term and low-dose exposure

• Published in: Environmental pollution (1987) Vol. 255; no. Pt 1; p. 113137
• Main Authors: Qu, Man, Zhao, Yunli, Zhao, Yingyue, Rui, Qi, Kong, Yan, Wang, Dayong
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2019
• Subjects: adverse effects; animal models; Animals; Caenorhabditis elegans; Caenorhabditis elegans - drug effects; Caenorhabditis elegans - genetics; chronic exposure; Down-Regulation; intestines; Intestines - drug effects; locomotion; Locomotion - drug effects; Locomotion - genetics; Long non-coding RNAs; Microplastics - toxicity; Molecular response; nanoplastics; Nanopolystyrene; non-coding RNA; Polystyrenes - toxicity; reactive oxygen species; Reactive Oxygen Species - metabolism; RNA Interference; RNA, Long Noncoding - genetics; RNA, Small Interfering - genetics; Signal Transduction; toxicity; Up-Regulation; Caenorhabditis elegans; Long non-coding RNAs; Nanopolystyrene; Molecular response

The potential adverse effects of nanoplastics, such as nanopolystyrene, have received the great attention recently. However, the molecular response of organisms to nanoplastics is still largely unknown. In this study, we employed Caenorhabditis elegans as an animal model to investigate the long non-...