Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents - Jia, Hui; Yang, Qian; Wang, Tao; Cao, Yu; Jiang, Qi-yu; Ma, Hong-da; Sun, Hui-wei; Hou, Ming-xiao; Yang, Yong-ping; Feng, Fan (Biochimica et biophysica acta, 2016)
Keywords: agar; Animals; Antineoplastic Agents, Phytogenic - pharmacology; Antineoplastic Combined Chemotherapy Protocols - pharmacology; breast neoplasms; Carcinoma, Hepatocellular - drug therapy; Carcinoma, Hepatocellular - enzymology; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - pathology; Cell Survival - drug effects; cell viability; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm - drug effects; Drug Resistance, Neoplasm - genetics; drug therapy; etoposide; Etoposide - pharmacology; flow cytometry; Gene Expression Regulation, Neoplastic; HCC; Hep G2 Cells; hepatoma; Humans; Inhibitory Concentration 50; Liver Neoplasms - drug therapy; Liver Neoplasms - enzymology; Liver Neoplasms - genetics; Liver Neoplasms - pathology; Male; MDR; MDR-related proteins; mice; Mice, SCID; MicroRNAs - genetics; MicroRNAs - metabolism; MiR-34a; multiple drug resistance; neoplasm cells; Niacinamide - analogs & derivatives; Niacinamide - pharmacology; Notch-1 pathway; P-glycoproteins; paclitaxel; Paclitaxel - pharmacology; Phenylurea Compounds - pharmacology; pro-apoptotic proteins; Protein Kinase Inhibitors - pharmacology; quantitative polymerase chain reaction; Quercetin - analogs & derivatives; Quercetin - pharmacology; Receptor, Notch1 - antagonists & inhibitors; Receptor, Notch1 - metabolism; Rhamnetin; signal transduction; Signal Transduction - drug effects; stress response; Transfection; Western blotting; Xenograft Model Antitumor Assays; Rhamnetin; MDR-related proteins; HCC; MDR; MiR-34a; Notch-1 pathway