Efficacy of repetitive transcranial magnetic stimulation in cognitive impairment of neurodegenerative diseases: a systematic review and meta-analysis

• Published in: BMC neurology Vol. 25; no. 1; pp. 295 - 14
• Main Authors: Zhang, Yu, Xu, Ke, Wang, Yulin, Shen, Yiwei, Liu, Zhengnan, Zhang, Chengguang, Zhou, Yan, Lv, Peizhu, Bai, Yan, Wang, Shun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.07.2025; BioMed Central; BMC
• Subjects: Activities of daily living; Alzheimer Disease - psychology; Alzheimer Disease - therapy; Alzheimer's disease; Analysis; Bias; Care and treatment; Clinical trials; Cognitive ability; Cognitive Dysfunction - etiology; Cognitive Dysfunction - therapy; Degeneration; Dementia; Depression, Mental; Diagnosis; Disease; DLPFC/non-DLPFC; Electrophysiology; Emotions; Evidence-based medicine; Handbooks; Humans; Intervention; Magnetic brain stimulation; Magnetic fields; Memory; Meta-analysis; Methods; Movement disorders; Nervous system; Neural networks; Neurodegenerative diseases; Neurodegenerative Diseases - complications; Neurodegenerative Diseases - psychology; Neurodegenerative Diseases - therapy; Parkinson Disease - complications; Parkinson Disease - psychology; Parkinson Disease - therapy; Parkinson's disease; Patient outcomes; Prefrontal cortex; Randomized Controlled Trials as Topic - methods; RTMS; Systematic review; Transcranial magnetic stimulation; Transcranial Magnetic Stimulation - methods; Treatment Outcome; China; Cognitive and emotional disorders; Parkinson's disease; DLPFC/non-DLPFC; Neurodegenerative diseases; Alzheimer's disease; RTMS; Meta-analysis

Currently, there is a lack of reliable evidence to prove the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in the cognitive and emotional domains of neurodegenerative diseases (ND), leading to the absence of a unified and effective rTMS treatment protocol or stimulation target...