Can the observed association between serum perfluoroalkyl substances and delayed menarche be explained on the basis of puberty-related changes in physiology and pharmacokinetics? - Wu, Huali; Yoon, Miyoung; Verner, Marc-André; Xue, Jianping; Luo, Man; Andersen, Melvin E.; Longnecker, Matthew P.; Clewell, Harvey J. (Environment international, 2015)
Keywords: Adolescent; adolescents; Age; Alkanesulfonic Acids; blood serum; Caprylates; Computer simulation; Cross-Sectional Studies; Environmental exposure; epidemiological studies; Epidemiology; excretion; Female; females; Fluorocarbons - blood; Fluorocarbons - pharmacokinetics; half life; Humans; Male; Mathematical models; Menarche; Menarche - physiology; menstruation; PBPK; Perfluoroalkyls; perfluorooctane sulfonic acid; perfluorooctanoic acid; PFA; PFOA; PFOS; pharmacokinetics; Physiology; Prevalence; Puberty - physiology; Serums; Sexual Maturation; toxicity; PBPK; Menarche; Environmental exposure; Female; PFOA; PFOS