Selectivity of major isoquinoline alkaloids from Chelidonium majus towards telomeric G-quadruplex: A study using a transition-FRET (t-FRET) assay - Noureini, Sakineh Kazemi; Esmaeili, Hosein; Abachi, Farzane; Khiali, Soraia; Islam, Barira; Kuta, Martyna; Saboury, Ali A.; Hoffmann, Marcin; Sponer, Jiri; Parkinson, Gary; Haider, Shozeb (Biochimica et biophysica acta. General subjects, 2017)
Keywords: adverse effects; Alkaloids - pharmacology; antineoplastic agents; Benzophenanthridines - pharmacology; Berberine; biobased products; Chelerythrine; Chelidonine; Chelidonium - chemistry; Chelidonium majus; Circular Dichroism; circular dichroism spectroscopy; Fluorescence Resonance Energy Transfer - methods; G-quadruplex; G-Quadruplexes; Humans; isoquinolines; Isoquinolines - pharmacology; ligands; MCF-7 Cells; messenger RNA; Models, Molecular; molecular models; oligonucleotides; Papaverine; quantitative polymerase chain reaction; Sanguinarine; stabilizers; Telomerase; Telomerase - antagonists & inhibitors; telomeres; Transition-FRET; Berberine; Chelerythrine; G-quadruplex; Chelidonine; Transition-FRET; Sanguinarine; Papaverine; Telomerase