High Prevalence of Chlamydia pneumoniae DNA in Peripheral Blood Mononuclear Cells in Patients with Cardiovascular Disease and in Middle-Aged Blood Donors

• Published in: The Journal of infectious diseases Vol. 178; no. 1; pp. 274 - 277
• Main Authors: Boman, Jens, Söderberg, Stefan, Forsberg, Jenny, Birgander, Lisbeth Slunga, Allard, Annika, Persson, Kenneth, Jidell, Erik, Kumlin, Urban, Juto, Per, Waldenström, Anders, Wadell, Göran
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 01.07.1998; University of Chicago Press; Oxford University Press
• Subjects: Adult; Aged; Aged, 80 and over; Antibodies; Antibodies, Bacterial - blood; Bacterial diseases; Bacterial endocarditis, myocarditis and pericarditis. Bacterial diseases of the aorta, limb vessels and lymphatic vessels; Bartonella; Biological and medical sciences; Blood; Blood donation; Blood Donors; Chlamydia Infections - complications; Chlamydia Infections - diagnosis; Chlamydia Infections - epidemiology; Chlamydia pneumoniae; Chlamydophila pneumoniae; Chlamydophila pneumoniae - genetics; Chlamydophila pneumoniae - immunology; Chlamydophila pneumoniae - isolation & purification; Concise Communications; Coronary Angiography; Coronary artery disease; Coronary Disease - complications; Coronary Disease - microbiology; Coronary Disease - surgery; DNA, Bacterial - blood; Female; Human bacterial diseases; Humans; Infections; Infectious diseases; Leukocytes, Mononuclear - microbiology; Male; Medical sciences; Middle Aged; Polymerase chain reaction; Prevalence; Serology; Human; Chlamydia pneumoniae; Prevalence; Chlamydiaceae; Antibody; Cardiovascular disease; Identification; Serology; Case control study; Method; Infection; Prospective; Polymerase chain reaction; Mononuclear cell; DNA; Bacteriosis; Chlamydiales; Bacteria; Chlamydiosis; Diagnosis; Blood donor

Nested polymerase chain reaction (nPCR) demonstrated the presence of Chlamydia pneumoniae-specific DNA in peripheral blood mononuclear cells (PBMC). PBMC samples were obtained from 103 consecutive patients (62 male, 41 female) aged 22–85 years (mean, 64) admitted for coronary angiography because of...