Relationship between the magnitude of IgE production in mice and conformational stability of the house dust mite allergen, Der p 2 - Nakamura, Hitomi; Ohkuri, Takatoshi; So, Takanori; Ueda, Tadashi (Biochimica et biophysica acta, 2016)
Keywords: ADAs (anti-drug antibodies); Allergen; allergens; Animals; antigen presentation; Antigen-Presenting Cells - immunology; Antigen-Presenting Cells - metabolism; Antigens, Dermatophagoides - chemistry; Antigens, Dermatophagoides - genetics; Antigens, Dermatophagoides - immunology; Arthropod Proteins - chemistry; Arthropod Proteins - genetics; Arthropod Proteins - immunology; blood serum; Conformational stability; denaturation; Der p 2; dust; dust mites; engineering; guanidines; Humans; immune response; Immunization; Immunogenicity; immunoglobulin E; Immunoglobulin E - blood; Immunoglobulin E - chemistry; Immunoglobulin E - immunology; major histocompatibility complex; Mice; Molecular Conformation; mutants; mutation; peptides; Protein Denaturation; proteinases; Pyroglyphidae - chemistry; Pyroglyphidae - immunology; T-lymphocytes; T-Lymphocytes - immunology; T-Lymphocytes - metabolism; vaccines; CD; Conformational stability; Der p 2; Immunogenicity; ADAs (anti-drug antibodies); Der p; HEL; Allergen