Reconstruction of low-resolution molecular structures from simulated atomic force microscopy images

• Published in: Biochimica et biophysica acta. General subjects Vol. 1864; no. 2; p. 129420
• Main Authors: Dasgupta, Bhaskar, Miyashita, Osamu, Tama, Florence
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2020
• Subjects: algorithms; Atomic force microscopy; Computational modeling; Gaussian mixture model; Monte-Carlo sampling; proteins; structure-activity relationships; Atomic force microscopy; Monte-Carlo sampling; Computational modeling; Gaussian mixture model

Atomic Force Microscopy (AFM) is an experimental technique to study structure-function relationship of biomolecules. AFM provides images of biomolecules at nanometer resolution. High-speed AFM experiments produce a series of images following dynamics of biomolecules. To further understand biomolecul...