Defining Regulatory Regions in the Rat Prolactin Gene Family Locus Using a Large P1 Genomic Clone

• Published in: Endocrinology (Philadelphia) Vol. 144; no. 11; pp. 4742 - 4754
• Main Authors: Öztürk, Arzu, Fresnoza, Agnes, Savoie, Amanda, Duckworth, Harry W, Duckworth, Mary Lynn
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Endocrine Society 01.11.2003; Oxford University Press
• Subjects: Amino Acid Sequence; Animals; Biological and medical sciences; Chromosome 17; Chromosome Mapping; Cloning; Cloning, Molecular; Decidua; Deoxyribonucleic acid; DNA; Feasibility Studies; Female; Fundamental and applied biological sciences. Psychology; Gene Expression; Gene sequencing; Genes; Genome; Genomics; Mice; Mice, Inbred Strains; Mice, Transgenic; Molecular Sequence Data; Multigene Family - genetics; Nucleotide sequence; Placenta; Placenta - metabolism; Placental Lactogen - genetics; Pregnancy; Prolactin; Prolactin - genetics; Proteins; Pseudogenes; Rats; Regulatory sequences; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Transgenes; Transgenic mice; Vertebrates: endocrinology; Vertebrata; Mammalia; Adenohypophyseal hormone; Gene; Rat; Family study; Prolactin; Animal; Rodentia; Regulatory sequence; Locus

Members of the large rat prolactin gene family located on chromosome 17 are expressed in one or more placental trophoblast cell types and maternal decidua at specific times during pregnancy. Studies to identify the factors involved in these highly specific developmental expression patterns, using li...