TDP-43 CSF Concentrations Increase Exponentially with Age in Metropolitan Mexico City Young Urbanites Highly Exposed to PM2.5 and Ultrafine Particles and Historically Showing Alzheimer and Parkinson’s Hallmarks. Brain TDP-43 Pathology in MMC Residents Is Associated with High Cisternal CSF TDP-43 Concentrations - Calderón-Garcidueñas, Lilian; Stommel, Elijah W.; Lachmann, Ingolf; Waniek, Katharina; Chao, Chih-Kai; González-Maciel, Angélica; García-Rojas, Edgar; Torres-Jardón, Ricardo; Delgado-Chávez, Ricardo; Mukherjee, Partha S. (Toxics (Basel), 2022)
Keywords: Air pollution; ALS; Alzheimer's disease; Alzheimer’s; Amyotrophic lateral sclerosis; Autopsies; Autopsy; Aβ1–42; Brain research; Brain-derived neurotrophic factor; Cerebrospinal fluid; Children; Dementia; DNA-binding protein; Emissions; Exposure; Medulla oblongata; Megacities; Motor nuclei; Movement disorders; Neurological diseases; Nitrogen dioxide; Olfactory bulb; Oxidative stress; Parkinson's disease; Particulate emissions; Particulate matter; Pathology; Pollution control; Pollution monitoring; Pons; Proteins; Public health; Reticular formation; Trends; Ultrafines; Young adults; α synuclein; Mexico; North America; Mexico City Mexico