The impact of developmental genes in non-syndromic cleft lip and/or palate

• Published in: Journal of the Turkish German Gynecological Association Vol. 24; no. 1; pp. 57 - 64
• Main Authors: Şahin Uysal, Nihal, Şahin, Feride İffet, Terzi, Yunus Kasım
• Format: Journal Article
• Language: English
• Published: Turkey Galenos Publishing House 01.03.2023; Galenos Publishing
• Subjects: Apoptosis; Cell division; Cell growth; Congenital diseases; Disease; Embryos; Genes; Genetic counseling; Genomes; Gynecology; Mutation; Pathogenesis; Review; Cleft lip and/or palate; prenatal evaluation; developmental genes

Non-syndromic cleft lip and/or palate (NSCL/P) is a congenital malformation with a prevalence of 1:700 births. It has a multifactorial etiology. Human craniofacial development takes place during the first 10 weeks of pregnancy. Normal craniofacial development arises from the convergence and fusion o...