A prospective, randomized pilot evaluation of topical triple antibiotic versus mupirocin for the prevention of uncomplicated soft tissue wound infection

• Published in: The American journal of emergency medicine Vol. 22; no. 1; pp. 1 - 3
• Main Authors: Hood, Robert, Shermock, Kenneth M, Emerman, Charles
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Elsevier Inc 2004; Elsevier; Elsevier Limited
• Subjects: Administration, Topical; Adult; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anti-Bacterial Agents - administration & dosage; antibiotic therapy; Antibiotics; Bacitracin - administration & dosage; Bacterial Infections - prevention & control; Biological and medical sciences; Chi-Square Distribution; Cost analysis; Cost estimates; Drug Combinations; Emergency medical care; Female; Humans; Infection; Infections; Intensive care medicine; Male; Medical sciences; Mupirocin - administration & dosage; Neomycin - administration & dosage; Ointments; Patients; Pilot Projects; Polymyxin B - administration & dosage; Prevention; prophylaxis; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; wound care; Wound healing; Wound Infection - prevention & control; Infection; wound care; antibiotic therapy; prophylaxis; Prevention; Local administration; Antibiotic; Intensive care; Mupirocin; Soft tissue; Wound; Comparative study; Resuscitation

Little data exists comparing the safety and efficacy of triple antibiotic ointment (TAO) and mupirocin for prevention of uncomplicated soft tissue wound infections. The purpose of this investigation was to conduct a pilot study of the relative safety, efficacy, and cost effectiveness of the 2 prepar...