A 30-Day Adjunct Wellness Intervention for the Management of Extra-Articular Symptoms of Rheumatoid Arthritis: A Formative Study
Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that emphasizing physical and mental wellness is equally crucial for improving functioning among people with RA. The purpose of this formative study i...
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Published in | Journal of evidence-based integrative medicine Vol. 27; pp. 2515690 - 2515690X221113330 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
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Los Angeles, CA
SAGE Publications
2022
SAGE PUBLICATIONS, INC SAGE Publishing |
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Abstract | Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that emphasizing physical and mental wellness is equally crucial for improving functioning among people with RA. The purpose of this formative study is to examine the feasibility of offering the wellness-based intervention (“KickStart30”) in patients with RA. Thirteen individuals with RA on targeted immune modulators (a biologic or JAK inhibitor) enrolled in the KickStart30 program. Participants completed self-report measures of RA-specific disability (eg, pain) and other functional areas (eg, mood) in a pre- versus post- intervention design. Paired samples t-tests (and Related-Samples Wilcoxon Signed Rank Tests for non-normal distributions) detected statistically significant results for 10 of 12 measures, including reductions in pain (M = 4.54 to M = 3.54; p = .025; BPI), functional disability (M = 0.94 to M = 0.73, p = .032; HAQ-II), cognitive and physical dysfunction (M = 25.46 to M = 13.54, p < .001; CPFQ), depressive symptoms (M = 9.31 to M = 5.54, p = .003; PHQ-9), anxiety (M = 5.69 to M = 3.23, p = .005; GAD-7), insomnia (M = 11.62 to M = 17.32, p = .007; Note: higher scores on the SCI indicate less insomnia), stress-related eating (M = 75.46 to M = 84.54, p = .021; Note: higher scores on the EADES indicate less stress-related eating), along with significant increases in mindfulness (M = 62.54 to M = 67.85, p = .040; MAAS), mental wellness (M = 4.46 to M = 5.69; HERO), and well-being (Md = 8.00 to Md = 5.00, p = .004; WHO-5). All significant measures had medium to large effect sizes (Cohen's d). The study gives preliminary support for the possibility that the adjunct intervention may have an effect. |
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AbstractList | Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that emphasizing physical and mental wellness is equally crucial for improving functioning among people with RA. The purpose of this formative study is to examine the feasibility of offering the wellness-based intervention (“KickStart30”) in patients with RA. Thirteen individuals with RA on targeted immune modulators (a biologic or JAK inhibitor) enrolled in the KickStart30 program. Participants completed self-report measures of RA-specific disability (eg, pain) and other functional areas (eg, mood) in a pre- versus post- intervention design. Paired samples t-tests (and Related-Samples Wilcoxon Signed Rank Tests for non-normal distributions) detected statistically significant results for 10 of 12 measures, including reductions in pain (M = 4.54 to M = 3.54; p = .025; BPI), functional disability (M = 0.94 to M = 0.73, p = .032; HAQ-II), cognitive and physical dysfunction (M = 25.46 to M = 13.54, p < .001; CPFQ), depressive symptoms (M = 9.31 to M = 5.54, p = .003; PHQ-9), anxiety (M = 5.69 to M = 3.23, p = .005; GAD-7), insomnia (M = 11.62 to M = 17.32, p = .007; Note: higher scores on the SCI indicate less insomnia), stress-related eating (M = 75.46 to M = 84.54, p = .021; Note: higher scores on the EADES indicate less stress-related eating), along with significant increases in mindfulness (M = 62.54 to M = 67.85, p = .040; MAAS), mental wellness (M = 4.46 to M = 5.69; HERO), and well-being (Md = 8.00 to Md = 5.00, p = .004; WHO-5). All significant measures had medium to large effect sizes (Cohen's d). The study gives preliminary support for the possibility that the adjunct intervention may have an effect. Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that emphasizing physical and mental wellness is equally crucial for improving functioning among people with RA. The purpose of this formative study is to examine the feasibility of offering the wellness-based intervention (“KickStart30”) in patients with RA. Thirteen individuals with RA on targeted immune modulators (a biologic or JAK inhibitor) enrolled in the KickStart30 program. Participants completed self-report measures of RA-specific disability (eg, pain) and other functional areas (eg, mood) in a pre- versus post- intervention design. Paired samples t- tests (and Related-Samples Wilcoxon Signed Rank Tests for non-normal distributions) detected statistically significant results for 10 of 12 measures, including reductions in pain ( M = 4.54 to M = 3.54; p = .025; BPI ), functional disability ( M = 0.94 to M = 0.73, p = .032 ; HAQ-II ), cognitive and physical dysfunction ( M = 25.46 to M = 13.54, p < .001; CPFQ ), depressive symptoms ( M = 9.31 to M = 5.54, p = .003; PHQ-9 ), anxiety ( M = 5.69 to M = 3.23, p = .005; GAD-7 ), insomnia ( M = 11.62 to M = 17.32, p = .007; Note: higher scores on the SCI indicate less insomnia), stress-related eating ( M = 75.46 to M = 84.54, p = .021; Note: higher scores on the EADES indicate less stress-related eating), along with significant increases in mindfulness ( M = 62.54 to M = 67.85, p = .040; MAAS ), mental wellness ( M = 4.46 to M = 5.69; HERO ), and well-being ( M d = 8.00 to M d = 5.00, p = .004; WHO-5 ). All significant measures had medium to large effect sizes (Cohen's d ). The study gives preliminary support for the possibility that the adjunct intervention may have an effect. Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that emphasizing physical and mental wellness is equally crucial for improving functioning among people with RA. The purpose of this formative study is to examine the feasibility of offering the wellness-based intervention (“KickStart30”) in patients with RA. Thirteen individuals with RA on targeted immune modulators (a biologic or JAK inhibitor) enrolled in the KickStart30 program. Participants completed self-report measures of RA-specific disability (eg, pain) and other functional areas (eg, mood) in a pre- versus post- intervention design. Paired samples t-tests (and Related-Samples Wilcoxon Signed Rank Tests for non-normal distributions) detected statistically significant results for 10 of 12 measures, including reductions in pain ( M = 4.54 to M = 3.54; p = .025; BPI), functional disability ( M = 0.94 to M = 0.73, p = .032 ; HAQ-II), cognitive and physical dysfunction ( M = 25.46 to M = 13.54, p < .001; CPFQ), depressive symptoms ( M = 9.31 to M = 5.54, p = .003; PHQ-9), anxiety ( M = 5.69 to M = 3.23, p = .005; GAD-7), insomnia ( M = 11.62 to M = 17.32, p = .007; Note: higher scores on the SCI indicate less insomnia), stress-related eating ( M = 75.46 to M = 84.54, p = .021; Note: higher scores on the EADES indicate less stress-related eating), along with significant increases in mindfulness ( M = 62.54 to M = 67.85, p = .040; MAAS), mental wellness ( M = 4.46 to M = 5.69; HERO), and well-being ( M d = 8.00 to M d = 5.00, p = .004; WHO-5). All significant measures had medium to large effect sizes (Cohen's d). The study gives preliminary support for the possibility that the adjunct intervention may have an effect. Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that emphasizing physical and mental wellness is equally crucial for improving functioning among people with RA. The purpose of this formative study is to examine the feasibility of offering the wellness-based intervention (“KickStart30”) in patients with RA. Thirteen individuals with RA on targeted immune modulators (a biologic or JAK inhibitor) enrolled in the KickStart30 program. Participants completed self-report measures of RA-specific disability (eg, pain) and other functional areas (eg, mood) in a pre- versus post- intervention design. Paired samples t- tests (and Related-Samples Wilcoxon Signed Rank Tests for non-normal distributions) detected statistically significant results for 10 of 12 measures, including reductions in pain ( M = 4.54 to M = 3.54; p = .025; BPI ), functional disability ( M = 0.94 to M = 0.73, p = .032 ; HAQ-II ), cognitive and physical dysfunction ( M = 25.46 to M = 13.54, p < .001; CPFQ ), depressive symptoms ( M = 9.31 to M = 5.54, p = .003; PHQ-9 ), anxiety ( M = 5.69 to M = 3.23, p = .005; GAD-7 ), insomnia ( M = 11.62 to M = 17.32, p = .007; Note: higher scores on the SCI indicate less insomnia), stress-related eating ( M = 75.46 to M = 84.54, p = .021; Note: higher scores on the EADES indicate less stress-related eating), along with significant increases in mindfulness ( M = 62.54 to M = 67.85, p = .040; MAAS ), mental wellness ( M = 4.46 to M = 5.69; HERO ), and well-being ( M d = 8.00 to M d = 5.00, p = .004; WHO-5 ). All significant measures had medium to large effect sizes (Cohen's d ). The study gives preliminary support for the possibility that the adjunct intervention may have an effect. |
Author | Rolin, Donna Jain, Rakesh Cole, Steven P. Hutson, Tara Laster, Andrew J. Murman, Nicole Jain, Saundra |
AuthorAffiliation | 4 Research Design Associates, Inc., Yorktown Heights, NY, USA 3 Arthritis & Osteoporosis Consultants of the Carolinas, Charlotte, NC, USA 1 12330 The University of Texas at Austin , Austin, TX, USA 2 12343 Texas Tech University Health Sciences Center , Lubbock, TX, USA |
AuthorAffiliation_xml | – name: 1 12330 The University of Texas at Austin , Austin, TX, USA – name: 4 Research Design Associates, Inc., Yorktown Heights, NY, USA – name: 2 12343 Texas Tech University Health Sciences Center , Lubbock, TX, USA – name: 3 Arthritis & Osteoporosis Consultants of the Carolinas, Charlotte, NC, USA |
Author_xml | – sequence: 1 givenname: Tara orcidid: 0000-0002-0489-9012 surname: Hutson fullname: Hutson, Tara email: t.hutson@utexas.edu – sequence: 2 givenname: Nicole surname: Murman fullname: Murman, Nicole – sequence: 3 givenname: Donna surname: Rolin fullname: Rolin, Donna – sequence: 4 givenname: Rakesh surname: Jain fullname: Jain, Rakesh – sequence: 5 givenname: Andrew J. surname: Laster fullname: Laster, Andrew J. – sequence: 6 givenname: Steven P. surname: Cole fullname: Cole, Steven P. – sequence: 7 givenname: Saundra surname: Jain fullname: Jain, Saundra |
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Snippet | Individuals with rheumatoid arthritis (RA) continually fall short of treatment targets using standard drug therapies alone. There is growing evidence that... |
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SubjectTerms | Disability Drug abuse Feasibility Generalized anxiety disorder Insomnia Intervention Learning disabled people Mental depression Mindfulness Original Manuscript Pain Rheumatoid arthritis Self report Stress |
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Title | A 30-Day Adjunct Wellness Intervention for the Management of Extra-Articular Symptoms of Rheumatoid Arthritis: A Formative Study |
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