Gene liposome nanocomplex-loaded dermal substitute promotes diabetic chronic wound healing and angiogenesis in rat

• Published in: Biomedicine & pharmacotherapy Vol. 163; p. 114794
• Main Authors: Wang, Yong, Ji, Jia-Ying, Guo, Kai, Zhang, Tao, Zhong, Xin-Cao, Zhuang, Ze-Ming, Zhong, Yu-Fan, Lin, Xiao-Ying, Du, Yong-Zhong, Chen, Jian, Tan, Wei-Qiang
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.07.2023
• Subjects: Angiogenesis; Animals; Collagen; Collagen - pharmacology; Diabetes Mellitus; Diabetic wound healing; Extracellular Matrix; Gene therapy; Hyaluronic acid; Liposomes - pharmacology; Rats; SDF-1α; Wound Healing; SDF-1α; Angiogenesis; Hyaluronic acid; Gene therapy; Collagen; Diabetic wound healing

The incidence of chronic diabetic wounds is increasing with the growing number of diabetic patients, and conventional wound dressings have proven to be ineffective in treating them. To address this challenge, researchers have developed artificial dermal substitutes using collagen and hyaluronic acid...