MicroRNAs play an important role in contributing to arsenic susceptibility in the chronically exposed individuals of West Bengal, India

• Published in: Environmental science and pollution research international Vol. 26; no. 27; pp. 28052 - 28061
• Main Authors: Banerjee, Nilanjana, Das, Subhadeep, Tripathy, Sucheta, Bandyopadhyay, Apurba K., Sarma, Nilendu, Bandyopadhyay, Arun, Giri, Ashok K.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2019; Springer Nature B.V
• Subjects: Aquatic Pollution; Arsenic; Arsenic - analysis; Arsenic Poisoning - epidemiology; Arsenic Poisoning - genetics; at-risk population; Atmospheric Protection/Air Quality Control/Air Pollution; biochemical pathways; bioinformatics; Biosynthesis; chronic exposure; Colorectal cancer; Colorectal carcinoma; colorectal neoplasms; Contamination; distress; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Exposure; Environmental Health; Environmental science; Exposure; eye diseases; eyes; gene expression regulation; Groundwater; groundwater contamination; Groundwater pollution; health effects assessments; Humans; India; India - epidemiology; Lesions; Lymphocytes; Lymphocytes T; Male; Metabolism; microRNA; MicroRNAs; MicroRNAs - genetics; Middle Aged; miRNA; quantitative polymerase chain reaction; Research Article; Signal transduction; Signaling; Skin; Skin diseases; Skin Diseases - epidemiology; skin lesions; T cell receptors; T-lymphocytes; Toxicity; Up-Regulation; Waste Water Technology; Water Management; Water Pollution Control; India; West Bengal India; Health effects; MicroRNA; Arsenic; Susceptibility; Skin lesions
• ISSN: 0944-1344; 1614-7499; 1614-7499
• DOI: 10.1007/s11356-019-05980-8

Arsenic exposure by groundwater contamination is a menace which threatens more than 26 million individuals of West Bengal. Interestingly, with similar levels of arsenic exposure, only 15–20% of the population show arsenic-induced skin lesions, the hallmarks of chronic arsenic toxicity, but the rest...