Disease fatality and bias in survival cohorts

• Published in: Environmental research Vol. 140; pp. 275 - 281
• Main Authors: Barry, Vaughn, Klein, Mitchel, Winquist, Andrea, Darrow, Lyndsey A., Steenland, Kyle
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.07.2015
• Subjects: Bias; Cohort Studies; Cross sections; Disease; disease incidence; disease occurrence; dose response; Environmental Exposure; Estimates; Exposure; Fatal; Fatalities; Fatality; Humans; Mortality; Probability; Regression; risk; Simulation; Survival Rate; Survivor cohort; Fatality; Simulation; Bias; Survivor cohort

Simulate how the effect of exposure on disease occurrence and fatality influences the presence and magnitude of bias in survivor cohorts, motivated by an actual survivor cohort under study. We simulated a cohort of 50,000 subjects exposed to a disease-causing exposure over time and followed forty ye...