Anti-aging function and molecular mechanism of Radix Astragali and Radix Astragali preparata via network pharmacology and PI3K/Akt signaling pathway - Gong, Pin; Wang, Danni; Cui, Dandan; Yang, Qian; Wang, Peipei; Yang, Wenjuan; Chen, Fuxin (Phytomedicine (Stuttgart), 2021)
Keywords: Aging; anti-aging properties; Astragalus membranaceus; body weight; galactose; genes; histopathology; inflammation; mice; molecular biology; network pharmacology PI3K/Akt signaling pathway; neurodegenerative diseases; oxidative stress; protein synthesis; Radix Astragali; Radix Astragali preparata; RAP; Radix Astragali; DL; PPI; MDA; PDB; MAPK8; OB; UPLC-Q-TOF/MS; CASP3; Aging; AKT1; MAPK1; D-gal; GSH; Radix Astragali preparata; H&E; MS; GO; PLA2; ESI-MS; SOD; SIRT1; RA; ROS; GAPDH; network pharmacology PI3K/Akt signaling pathway; TCM