Antigenic changes among the predominantly circulating C/Sao Paulo lineage strains of influenza C virus in Yamagata, Japan, between 2015 and 2018

• Published in: Infection, genetics and evolution Vol. 81; p. 104269
• Main Authors: Matsuzaki, Yoko, Shimotai, Yoshitaka, Kadowaki, Yoko, Sugawara, Kanetsu, Hongo, Seiji, Mizuta, Katsumi, Nishimura, Hidekazu
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2020
• Subjects: Amino Acid Sequence; Antigenic variant; Antigenic Variation - genetics; Antigens, Viral - genetics; Asia; Australia; bioactive properties; Brazil; Disease Outbreaks; Epidemiology; esterases; Europe; Gammainfluenzavirus - genetics; glycoproteins; Hemagglutination Inhibition Tests - methods; Hemagglutinin Glycoproteins, Influenza Virus - genetics; hemagglutinins; Hemagglutinins, Viral - genetics; Humans; infection; influenza; Influenza C virus; Influenza, Human - virology; Japan; monoclonal antibodies; mutation; pathogens; Phylogeny; Sequence Analysis, DNA - methods; Surveillance; Viral Fusion Proteins - genetics; viruses; Australia; Asia; Europe; Japan; Brazil; HI; 3D; Influenza C virus; Antigenic variant; Surveillance; HA; Epidemiology; HE; MAb

Influenza C virus is a pathogen that causes acute respiratory illness in children and results in the hospitalization of infants. The antigenicity of the hemagglutinin esterase (HE) glycoprotein is highly stable, and it is not yet known whether antigenic changes contribute to the worldwide transmissi...