Pharmacokinetics and anticoccidial activity of ethanamizuril in broiler chickens

• Published in: Veterinary parasitology Vol. 289; p. 109318
• Main Authors: Fu, Yikai, Zhou, Junwen, Zhang, Lifang, Fei, Chenzhong, Wang, Xiaoyang, Wang, Mi, Wang, Chunmei, Zhang, Keyu, Xue, Feiqun, Liu, Yingchun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2021
• Subjects: Animals; Anticoccidial index; Area Under Curve; body weight changes; Cecal contents; Chickens - parasitology; coccidiosis; Coccidiosis - drug therapy; Coccidiosis - parasitology; Coccidiosis - veterinary; coccidiostats; Coccidiostats - pharmacokinetics; Coccidiostats - therapeutic use; diarrhea; Drug Tapering; Eimeria tenella; Ethanamizuril; Gastrointestinal Contents - chemistry; Half-Life; mortality; oocysts; Pharmacokinetics; Poultry Diseases - drug therapy; Poultry Diseases - parasitology; therapeutics; Triazines - administration & dosage; Triazines - pharmacokinetics; Triazines - therapeutic use; UPLC; veterinary parasitology; Ethanamizuril; Anticoccidial index; Pharmacokinetics; UPLC; Cecal contents

•The concentrations of ethanamizuril in chicken cecal contents were detected.•The pharmacokinetic parameters of ethanamizuril in contents were analyzed.•Anticoccidial efficacy of ethanamizuril to challenged chickens was evaluated. The treatment effect of ethanamizuril (EZL) to broiler chickens exper...