Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy

Plasmodium, the aetiologic agent of malaria, cannot synthesize purines de novo, and hence depends upon salvage from the host. Here we describe the molecular cloning and functional expression in Xenopus oocytes of the first purine transporter to be identified in this parasite. This 422-residue protei...

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Bibliographic Details
Published inBiochemical journal Vol. 349; no. Pt 1; pp. 67 - 75
Main Authors Parker, M D, Hyde, R J, Yao, S Y, McRobert, L, Cass, C E, Young, J D, McConkey, G A, Baldwin, S A
Format Journal Article
LanguageEnglish
Published England 01.07.2000
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