Usefulness of Ultrasonography in Diagnosing Congenital Adrenal Hyperplasia in Neonates

The size of the right adrenal gland was ultrasonographically evaluated in nine neonates, who had elevated filter paper 17-hydroxyprogesterone concentrations in the neonatal screening and/or clinical presentation with genital hyperpigmentation. Ultrasonograms revealed that three of these neonates had...

Full description

Saved in:
Bibliographic Details
Published inClinical Pediatric Endocrinology Vol. 2; no. 2; pp. 99 - 105
Main Authors Wataki, Kunio, Ohnishi, Hisashi, Konda, Susumu, Yasuda, Toshiyuki, Miyamoto, Shigeki, Sanayama, Kazunori, Sasaki, Nozomu, Niimi, Hiroo
Format Journal Article
LanguageEnglish
Japanese
Published The Japanese Society for Pediatric Endocrinology 1993
Subjects
congenital adrenal hyperplasia
neonatal adrenal glands
neonatal screening
ultrasonography
Online AccessGet full text

Cover

Abstract The size of the right adrenal gland was ultrasonographically evaluated in nine neonates, who had elevated filter paper 17-hydroxyprogesterone concentrations in the neonatal screening and/or clinical presentation with genital hyperpigmentation. Ultrasonograms revealed that three of these neonates had an enlarged adrenal gland, and based on subsequent hormonal measurements and their clinical signs, all three were diagnosed as congenital adrenal hyperplasia due to a 21-hydroxylase deficiency. Sonography also revealed that the adrenal gland of the remaining six neonates was normal in size and they also were found to be hormonally normal. We conclude that sonographic measurement of the adrenal gland is a useful adjunct to achieving the diagnosis of congenital adrenal hyperplasia in the neonatal period.
AbstractList The size of the right adrenal gland was ultrasonographically evaluated in nine neonates, who had elevated filter paper 17-hydroxyprogesterone concentrations in the neonatal screening and/or clinical presentation with genital hyperpigmentation. Ultrasonograms revealed that three of these neonates had an enlarged adrenal gland, and based on subsequent hormonal measurements and their clinical signs, all three were diagnosed as congenital adrenal hyperplasia due to a 21-hydroxylase deficiency. Sonography also revealed that the adrenal gland of the remaining six neonates was normal in size and they also were found to be hormonally normal. We conclude that sonographic measurement of the adrenal gland is a useful adjunct to achieving the diagnosis of congenital adrenal hyperplasia in the neonatal period.
Author Yasuda, Toshiyuki
Niimi, Hiroo
Wataki, Kunio
Konda, Susumu
Miyamoto, Shigeki
Sasaki, Nozomu
Sanayama, Kazunori
Ohnishi, Hisashi
Author_xml – sequence: 1
  fullname: Wataki, Kunio
  organization: Department of Pediatrics, School of Medicine, Chiba University
– sequence: 2
  fullname: Ohnishi, Hisashi
  organization: Department of Pediatrics, School of Medicine, Chiba University
– sequence: 3
  fullname: Konda, Susumu
  organization: Department of Pediatrics, School of Medicine, Chiba University
– sequence: 4
  fullname: Yasuda, Toshiyuki
  organization: Department of Pediatrics, School of Medicine, Chiba University
– sequence: 5
  fullname: Miyamoto, Shigeki
  organization: Division of Endocrinology, Chiba Children's Hospital
– sequence: 6
  fullname: Sanayama, Kazunori
  organization: Department of Pediatrics, Narita Red Cross Hospital
– sequence: 7
  fullname: Sasaki, Nozomu
  organization: Division of Endocrinology, Chiba Children's Hospital
– sequence: 8
  fullname: Niimi, Hiroo
  organization: Department of Pediatrics, School of Medicine, Chiba University
BookMark eNo9UE1LAzEQDaJg_QB_wh69bE2yH8nclGpVEL1YryFmJ9uUbbIk20P_vSlVGYYHM2_eY94FOfXBIyE3jM4ZB3FnRpzzOcAJmbGqFqWoGnlKZhSYLBtRwTm5SGlDKQfa0hn5WiW0u8FjSkWwxWqYok7Bhz7qcb0vnC8ene59SM73xSL4Hr2b9FA8dBF9xpf9iHEcdHL6QH7H4PWE6YqcWT0kvP7FS7JaPn0uXsq3j-fXxcNbaeqWQSlsa2pRCdEgaysAKS1y810z5NBxCVYgCkkNRysZdlVTA9NI0ZqWdhKhuiS3R10TQ0oRrRqj2-q4V4yqQx4q56G4ggN1eaRusXNGD8EPzqPahF3MjyRldsLkiVMskxXNCVGeockNoCijDWfQSJqF7o9CmzTpHv8ddZycGfDgmCW4-qt8_b9a66jQVz8S3IOU
CitedBy_id crossref_primary_10_1080_14767058_2019_1594188
ContentType Journal Article
Copyright The Japanese Society for Pediatric Endocrinology
Copyright_xml – notice: The Japanese Society for Pediatric Endocrinology
CorporateAuthor Department of Pediatrics
Chiba
Narita Red Cross Hospital
Japan
Chiba Children's Hospital
School of Medicine
Chiba University
Division of Endocrinology
CorporateAuthor_xml – name: School of Medicine
– name: Division of Endocrinology
– name: Chiba
– name: Chiba University
– name: Chiba Children's Hospital
– name: Department of Pediatrics
– name: Japan
– name: Narita Red Cross Hospital
DBID AAYXX
CITATION
DOI 10.1297/cpe.2.99
DatabaseName CrossRef
DatabaseTitle CrossRef
DatabaseTitleList

DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1347-7358
EndPage 105
ExternalDocumentID 10_1297_cpe_2_99
cu7clini_1993_000202_005_0099_0105219580
article_cpe1992_2_2_2_2_99_article_char_en
GroupedDBID ---
29B
2WC
53G
5GY
6J9
ABDBF
ABPTK
ADBBV
ADRAZ
AEGXH
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BKOMP
CS3
DIK
E3Z
EBD
EBS
EJD
ESX
GX1
HYE
JMI
JSF
JSH
KQ8
M48
MOJWN
M~E
OK1
QF4
QN7
RJT
RNS
RPM
RYR
RZJ
TKC
TR2
TUS
W2D
XSB
AAYXX
CITATION
PGMZT
ID FETCH-LOGICAL-c4619-7f6c473775e1639988fe2cb41e29d289f7ee780c2ef81ed35491ae0efc60d8e93
ISSN 0918-5739
IngestDate Fri Aug 23 01:47:41 EDT 2024
Fri May 31 15:04:10 EDT 2024
Wed Apr 05 13:26:46 EDT 2023
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed false
IsScholarly true
Issue 2
Language English
Japanese
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c4619-7f6c473775e1639988fe2cb41e29d289f7ee780c2ef81ed35491ae0efc60d8e93
OpenAccessLink https://www.jstage.jst.go.jp/article/cpe1992/2/2/2_2_99/_article/-char/en
PageCount 7
ParticipantIDs crossref_primary_10_1297_cpe_2_99
medicalonline_journals_cu7clini_1993_000202_005_0099_0105219580
jstage_primary_article_cpe1992_2_2_2_2_99_article_char_en
PublicationCentury 1900
PublicationDate 1993
19930000
1993-00-00
PublicationDateYYYYMMDD 1993-01-01
PublicationDate_xml – year: 1993
  text: 1993
PublicationDecade 1990
PublicationTitle Clinical Pediatric Endocrinology
PublicationTitleAlternate Clinical Pediatric Endocrinology
PublicationYear 1993
Publisher The Japanese Society for Pediatric Endocrinology
Publisher_xml – name: The Japanese Society for Pediatric Endocrinology
References 2. Wataki K, Ohnishi H, Miyamoto H, Yasuda T, Niimi H. Ultrasonographic measurement of the normal neonatal adrenal glands. Acta Paediatr Jpn 1991; 95: 2331-5 (in Japanese).
5. Sivit CJ, Hung W, Taylor GA, Catena LM, Brown-Jones C, Kushner DC. Sonography in neonatal congenital adrenal hyperplasia. AJR 1991; 156: 141-3.
7. Hauffa BP, Menzel D, Stolecke H. Agerelated changes in adrenal size during the first year of life in normal newborns, infants and patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: comparison of ultrasound and hormonal parameters. Eur J Pediatr 1988; 148: 43-9.
9. Mizuseki K, Nakamura Y, Goto S, Kobayashi H, Mannami M, Kondo T, Sonographic screening for congenital adrenal hyperplasia. Jpn. J. Clin. Urol. 1992; 46: 331-4 (in Japanese).
1. Strachan T. Molecular pathology of congenital adrenal hyperplasia. Clin Endocrinol (Oxf) 1990; 32: 373-93.
4. Ghiacy S, Dubbins PA, Baumer H. Ultrasound demonstration of congenital adrenal hyperplasia. J Clin Ultrasound 1985; 13: 419-20.
6. Bryan PJ, Caldamone AA, Morrison SC, Yulish BS, Owens R. Ultrasound findings in the adreno-genital syndrome (congenital adrenal hyperplasia). J Ultrasound Med 1988; 7: 675-9.
8. Menzel D, Hauffa BP. Changes in size and sonographic characteristics of the adrenal glands during the first year of life and the sonographic diagnosis of adrenal hyperplasia in infants with 21-hydroxylase deficiency. J Clin Ultrasound 1990; 18: 619-25.
3. Oppenheimer DA, Carroll BA, Yousem S. Sonography of the normal neonatal adrenal gland. Radiology 1983; 146: 157-60.
References_xml
SSID ssj0029060
ssib023156991
Score 1.3551143
Snippet The size of the right adrenal gland was ultrasonographically evaluated in nine neonates, who had elevated filter paper 17-hydroxyprogesterone concentrations in...
SourceID crossref
medicalonline
jstage
SourceType Aggregation Database
Publisher
StartPage 99
SubjectTerms congenital adrenal hyperplasia
neonatal adrenal glands
neonatal screening
ultrasonography
Title Usefulness of Ultrasonography in Diagnosing Congenital Adrenal Hyperplasia in Neonates
URI https://www.jstage.jst.go.jp/article/cpe1992/2/2/2_2_99/_article/-char/en
http://mol.medicalonline.jp/library/journal/download?GoodsID=cu7clini/1993/000202/005&name=0099-0105e
Volume 2
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
ispartofPNX Clinical Pediatric Endocrinology, 1993, Vol.2(2), pp.99-105
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3da9RAEF_OKlIQ8at4fhHBt5Az2WyyyZMUrRRLK8Kd1qcl2ezSq21y3CUP-hf5ZzqT3XycilTlIHfkNmEzM5mdmZ35DSEvNGc65yHzJOhHj1Hpe1mklRdFKs8jpbMswELh45P4cMHenUank8n3UdZSU-cz-e23dSX_wlU4B3zFKtm_4Gx_UzgBv4G_cAQOw_FKPF5slG4uWmUFNt_iol5nYD5bEGqMZLwxiXRmbx-rqLBFiLuP1dsIKgw-6HrV1lHi4BOFkXSbU9iBF3SFk31LD_egLCpQNdvx-KOmXFbup6wGg3SIZm-wU5P7_qzEQNew_QQkatyjahQMmFcw4GvzZel-zjaNPV_Y4rywl5u2jg1Wd-yauZVv-qfZ2ThkkHgRN4hGM2W0cMi4x0OD6d6paTqSRjpSuWk6WryDtob713WBtnjDcqVmdNZdsIWyLRvelqIKfCzRbtBS-IoEmtAC24hShOXxr5HrlINPidv_H3rNBUZyFKdpn1yEGPptdK97OAt7DNN42U1iyxC6cQ6-AII83Lo0-3MGJ2Vk6szvkNvWR3H2jcDdJZPz7B65eWyzMO6Tj4PcOZV2fpI7Z1k6g9w5g9w5Vu6ckdzh4E7uHpDF24P560PP9ufwJAO_2-M6loyHnEcqQEM3SbSiMmeBomkBjrzmSvHEl1TpJFBFGLE0yJSvtIz9IlFpuEd2yqpUD4kT5xpchaKQWiNAJMvAcALt4ecsLiSokyl53hFLrAwMi0D3FQgqgKCCijSdktRQsR9hX0wcgVnWovsAR_u_zrI1qJIpebVFeGHf8o24qmA8-u87PCa7JpsW43tPyE69btRTsHjr_FkrbD8A3-yycQ
link.rule.ids 315,786,790,4043,27956,27957,27958
linkProvider Colorado Alliance of Research Libraries
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Usefulness+of+Ultrasonography+in+Diagnosing+Congenital+Adrenal+Hyperplasia+in+Neonates&rft.jtitle=Clinical+Pediatric+Endocrinology&rft.au=Kunio+Wataki&rft.au=Hisashi+Ohnishi&rft.au=Susumu+Konda&rft.au=Toshiyuki+Yasuda&rft.date=1993&rft.pub=The+Japanese+Society+for+Pediatric+Endocrinology&rft.issn=0918-5739&rft.eissn=1347-7358&rft.volume=2&rft.issue=2&rft.spage=99&rft.epage=105&rft_id=info:doi/10.1297%2Fcpe.2.99&rft.externalDocID=cu7clini_1993_000202_005_0099_0105219580
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0918-5739&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0918-5739&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0918-5739&client=summon