Therapeutic effect of double-filtration plasmapheresis combined with methylprednisolone to treat diffuse proliferative lupus nephritis

• Published in: Journal of clinical apheresis Vol. 31; no. 4; pp. 375 - 380
• Main Authors: Li, MinXia, Wang, YuanDa, Qiu, Qiang, Wei, RiBao, Gao, YuWei, Zhang, Li, Wang, Yong, Zhang, XueGuang, Chen, XiangMei
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.08.2016; Wiley Subscription Services, Inc
• Subjects: Case-Control Studies; complement C3; Dose-Response Relationship, Drug; double-filtration plasmapheresis; Humans; lupus nephritis; Lupus Nephritis - therapy; methylprednisolone; Methylprednisolone - therapeutic use; Mycophenolic Acid - therapeutic use; Plasmapheresis - methods; Remission Induction - methods; Secondary Prevention - methods; Treatment Outcome; methylprednisolone; lupus nephritis; complement C3; double-filtration plasmapheresis

Objective: The efficacy of double‐filtration plasmapheresis (DFPP), combined with methylprednisolone, to treat diffuse proliferative lupus nephritis (LN) was studied. Methods: Twenty‐four patients who were admitted to the hospital and diagnosed with diffuse proliferative LN (LN Class IV‐G(A)) throug...