Metabolomics‐identified metabolites associated with body mass index and prospective weight gain among Mexican American women

• Published in: Obesity science & practice Vol. 2; no. 3; pp. 309 - 317
• Main Authors: Zhao, H., Shen, J., Djukovic, D., Daniel‐MacDougall, C., Gu, H., Wu, X., Chow, W. ‐H.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.09.2016; John Wiley and Sons Inc
• Subjects: Acetylcholine; Asparagine; Body mass index; Body mass index (BMI); Body weight gain; Chronic illnesses; Dietary fiber; Glutamic acid; Kynurenic acid; Leucine; Metabolic disorders; Metabolic pathways; Metabolites; Metabolomics; Mexican Americans; Molecular modelling; Obesity; Original; Serine; Smoking; Studies; Uric acid; weight gain; Mexican Americans; metabolites; Body mass index (BMI); weight gain

Summary Objective Obesity is a metabolic disease. However, the underlying molecular mechanisms linking metabolic profiles and weight gain are largely unknown. Methods Here, we used semi‐targeted metabolomics to assay 156 metabolites selected from 25 key metabolic pathways in plasma samples from 300...