Magnetic resonance imaging biomarkers of cerebrospinal fluid tracer dynamics in idiopathic normal pressure hydrocephalus

• Published in: Brain communications Vol. 2; no. 2; p. fcaa187
• Main Authors: Eide, Per Kristian, Pripp, Are H, Ringstad, Geir
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.01.2020
• Subjects: Original; idiopathic normal pressure hydrocephalus; glymphatic system; MRI biomarkers; ICP; cerebrospinal fluid

Abstract Disturbed clearance of toxic metabolites from the brain via cerebrospinal fluid is emerging as an important mechanism behind dementia and neurodegeneration. To this end, magnetic resonance imaging work-up of dementia diseases is largely focused on anatomical derangements of the brain. This...