Enhanced Viral Replication by Cellular Replicative Senescence

• Published in: Immune network Vol. 16; no. 5; pp. 286 - 295
• Main Authors: Kim, Ji-Ae, Seong, Rak-Kyun, Shin, Ok Sarah
• Format: Journal Article
• Language: English
• Published: Korea (South) 대한면역학회 01.10.2016; The Korean Association of Immunologists
• Subjects: Original; 면역학; Senescence; VZV; SIRT1; Influenza

Cellular replicative senescence is a major contributing factor to aging and to the development and progression of aging-associated diseases. In this study, we sought to determine viral replication efficiency of influenza virus (IFV) and Varicella Zoster Virus (VZV) infection in senescent cells. Prim...