Noninvasive assessment of articular cartilage surface damage using reflected polarized light microscopy

• Published in: Journal of biomedical optics Vol. 22; no. 6; p. 065001
• Main Authors: Huynh, Ruby N, Nehmetallah, George, Raub, Christopher B
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.06.2017
• Subjects: Animals; Birefringence; Cartilage, Articular - diagnostic imaging; Cattle; Chondrocytes - cytology; Microscopy, Polarization; Osteoarthritis - diagnostic imaging; articular cartilage; polarization; microscopy; reflectance; surfaces

Articular surface damage occurs to cartilage during normal aging, osteoarthritis, and in trauma. A noninvasive assessment of cartilage microstructural alterations is useful for studies involving cartilage explants. This study evaluates polarized reflectance microscopy as a tool to assess surface dam...